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Antioxidant and anticholinesterase activities of five wild mushroom species with total bioactive contents.
Tel G, Ozturk M, Duru ME, Turkoglu A.
Pharm Biol. 2015 Feb 27:1-7. [Epub ahead of print]

Biochemical characterization and antioxidant and antiproliferative activities of different ganoderma collections.
Saltarelli R, Ceccaroli P, Buffalini M, Vallorani L, Casadei L, Zambonelli A, Iotti M, Badalyan S, Stocchi V.
J Mol Microbiol Biotechnol. 2015;25(1):16-25. doi: 10.1159/000369212. Epub 2015 Feb 3.

Structural characterization and antioxidant activity of a heteropolysaccharide from Ganoderma capense.
Yi P, Li N, Wan JB, Zhang D, Li M, Yan C.
Carbohydr Polym. 2015 May 5;121:183-9. doi: 10.1016/j.carbpol.2014.11.034. Epub 2014 Nov 24.

Anti-inflammatory and hepatoprotective effects of Ganoderma lucidum polysaccharides on carbon tetrachloride-induced hepatocyte damage in common carp (Cyprinus carpio L.).
Liu YJ, Du JL, Cao LP, Jia R, Shen YJ, Zhao CY, Xu P, Yin GJ.
Int Immunopharmacol. 2015 Mar;25(1):112-20. doi: 10.1016/j.intimp.2015.01.023. Epub 2015 Jan 29.

Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities.
Ferreira IC, Heleno SA, Reis FS, Stojkovic D, Queiroz MJ, Vasconcelos MH, Sokovic M.
Phytochemistry. 2014 Nov 5. pii: S0031-9422(14)00415-4. doi: 10.1016/j.phytochem.2014.10.011. [Epub ahead of print] Review.

A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp.
Xia Q, Zhang H, Sun X, Zhao H, Wu L, Zhu D, Yang G, Shao Y, Zhang X, Mao X, Zhang L, She G.
Molecules. 2014 Oct 30;19(11):17478-535. doi: 10.3390/molecules191117478.

Fungal beta glucan protects radiation induced DNA damage in human lymphocytes.
Pillai TG, Maurya DK, Salvi VP, Janardhanan KK, Nair CK.
Ann Transl Med. 2014 Feb;2(2):13. doi: 10.3978/j.issn.2305-5839.2014.02.02.

Unusual prenylated phenols with antioxidant activities from Ganoderma cochlear.
Peng X, Liu J, Wang C, Han Z, Shu Y, Li X, Zhou L, Qiu M.
Food Chem. 2015 Mar 15;171:251-7. doi: 10.1016/j.foodchem.2014.08.127. Epub 2014 Sep 8.

The level of elements and antioxidant activity of commercial dietary supplement formulations based on edible mushrooms.
Stilinovi? N, ?krbi? B, ?ivan?ev J, Mrmo? N, Pavlovi? N, Vukmirovi? S.
Food Funct. 2014 Dec;5(12):3170-8. doi: 10.1039/c4fo00703d.

Modulatory effect of crude aqueous extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes), on hematological and antioxidant indices in Plasmodium berghei-infected mice.
Oluba OM, Adebisi KE, Eidangbe GO, Odutuga AA, Onyeneke EC.
Int J Med Mushrooms. 2014;16(5):499-506.

Development of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (Higher Basidiomycetes) polysaccharides injection formulation.
Jiang Y, He A, Liu Y, Xie B, Li Y, Deng Y, Liu X, Liu Q.
Int J Med Mushrooms. 2014;16(5):411-9.

Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells.
Choi S, Nguyen VT, Tae N, Lee S, Ryoo S, Min BS, Lee JH.
Toxicol Appl Pharmacol. 2014 Nov 1;280(3):434-42. doi: 10.1016/j.taap.2014.09.007. Epub 2014 Sep 16.

Antioxidant activity of polysaccharide extracted from Ganoderma lucidum using response surface methodology.
Kan Y, Chen T, Wu Y, Wu J, Wu J.
Int J Biol Macromol. 2015 Jan;72:151-7. doi: 10.1016/j.ijbiomac.2014.07.056. Epub 2014 Aug 19.

Optimization of laccase production by two strains of Ganoderma lucidum using phenolic and metallic inducers.
Kuhar F, Papinutti L.
Rev Argent Microbiol. 2014 Apr-Jun;46(2):144-9. doi: 10.1016/S0325-7541(14)70063-X.

Inflammatory modulation effect of glycopeptide from Ganoderma capense (Lloyd) Teng.
Zhou Y, Chen S, Ding R, Yao W, Gao X.
Mediators Inflamm. 2014;2014:691285. doi: 10.1155/2014/691285. Epub 2014 May 22.

Solid-substrate fermentation of wheat grains by mycelia of indigenous species of the genus Ganoderma (higher Basidiomycetes) to enhance the antioxidant activities.
Subramaniam S, Sabaratnam V, Kuppusamy UR, Tan YS.
Int J Med Mushrooms. 2014;16(3):259-67.

Biological activity of Ganoderma lucidum basidiocarps cultivated on alternative and commercial substrate.
Cilerd?i? J, Vukojevi? J, Staji? M, Stanojkovi? T, Glamo?lija J.
J Ethnopharmacol. 2014 Aug 8;155(1):312-9. doi: 10.1016/j.jep.2014.05.036. Epub 2014 May 29.

Improving Training Condition Assessment in Endurance Cyclists: Effects of Ganoderma lucidum and Ophiocordyceps sinensis Dietary Supplementation.
Rossi P, Buonocore D, Altobelli E, Brandalise F, Cesaroni V, Iozzi D, Savino E, Marzatico F.
Evid Based Complement Alternat Med. 2014;2014:979613. doi: 10.1155/2014/979613. Epub 2014 Apr 1.

Improved production, purification and bioactivity of a polysaccharide from submerged cultured Ganoderma lucidum.
Zhou H, Liu G, Huang F, Wu X, Yang H.
Arch Pharm Res. 2014 Dec;37(12):1530-7. doi: 10.1007/s12272-014-0391-8. Epub 2014 Apr 16.

Wild Mushrooms in Nepal: Some Potential Candidates as Antioxidant and ACE-Inhibition Sources.
Hai Bang T, Suhara H, Doi K, Ishikawa H, Fukami K, Parajuli GP, Katakura Y, Yamashita S, Watanabe K, Adhikari MK, Manandhar HK, Kondo R, Shimizu K.
Evid Based Complement Alternat Med. 2014;2014:195305. doi: 10.1155/2014/195305. Epub 2014 Jan 28.

Effects of Selenium-Enriched Protein from Ganoderma lucidum on the Levels of IL-1 β and TNF- α , Oxidative Stress, and NF- κ B Activation in Ovalbumin-Induced Asthmatic Mice.
Min-Chang G, Wei-Hong T, Zhen X, Jie S.
Evid Based Complement Alternat Med. 2014;2014:182817. doi: 10.1155/2014/182817. Epub 2014 Feb 10.

Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism.
Phan CW, David P, Naidu M, Wong KH, Sabaratnam V.
Crit Rev Biotechnol. 2014 Mar 24. [Epub ahead of print]

Acetylation and carboxymethylation of the polysaccharide from Ganoderma atrum and their antioxidant and immunomodulating activities.
Chen Y, Zhang H, Wang Y, Nie S, Li C, Xie M.
Food Chem. 2014 Aug 1;156:279-88. doi: 10.1016/j.foodchem.2014.01.111. Epub 2014 Feb 7.

Immunomodulatory of selenium nano-particles decorated by sulfated Ganoderma lucidum polysaccharides.
Wang J, Zhang Y, Yuan Y, Yue T.
Food Chem Toxicol. 2014 Jun;68:183-9. doi: 10.1016/j.fct.2014.03.003. Epub 2014 Mar 10.

Ganoderma lucidum polysaccharides supplementation attenuates exercise-induced oxidative stress in skeletal muscle of mice.
Zhonghui Z, Xiaowei Z, Fang F.
Saudi J Biol Sci. 2014 Apr;21(2):119-23. doi: 10.1016/j.sjbs.2013.04.004. Epub 2013 Apr 23.

Effect of ultrasonic extraction conditions on antioxidative and immunomodulatory activities of a Ganoderma lucidum polysaccharide originated from fermented soybean curd residue.
Shi M, Yang Y, Hu X, Zhang Z.
Food Chem. 2014 Jul 15;155:50-6. doi: 10.1016/j.foodchem.2014.01.037. Epub 2014 Jan 23.

Immunostimulatory activities of β-d-glucan from Ganoderma Lucidum.
Wang J, Yuan Y, Yue T.
Carbohydr Polym. 2014 Feb 15;102:47-54. doi: 10.1016/j.carbpol.2013.10.087. Epub 2013 Nov 6.

Ganodermasides C and D, two new anti-aging ergosterols from spores of the medicinal mushroom Ganoderma lucidum.
Weng Y, Lu J, Xiang L, Matsuura A, Zhang Y, Huang Q, Qi J.
Biosci Biotechnol Biochem. 2011;75(4):800-3.

[Effect of different light of LED light quality on growth and antioxidant enzyme activities of Ganoderma lucidum].
Wang L, Chen X, Wang Q, Hao J, Lan J.
Zhongguo Zhong Yao Za Zhi. 2011 Sep;36(18):2471-4. Chinese.

Antimicrobial properties, antioxidant activity and cytotoxicity of ethanol-soluble acidic components from Ganoderma atrum.
Li WJ, Nie SP, Liu XZ, Zhang H, Yang Y, Yu Q, Xie MY.
Food Chem Toxicol. 2011 Dec 16;50(3-4):689-694.

Structural characterization and antioxidative activity of low-molecular-weights beta-1,3-glucan from the residue of extracted Ganoderma lucidum fruiting bodies.
Kao PF, Wang SH, Hung WT, Liao YH, Lin CM, Yang WB.
J Biomed Biotechnol. 2012;2012:673764. Epub 2011 Dec 6.

Determination of the antioxidant activity and polyphenol contents of wild Lingzhi or reishi medicinal mushroom, ganoderma lucidum (W.Curt. Fr.) P. Karst. (higher basidiomycetes) from central himalayan hills of India.
Mohsin M, Negi P, Ahmed Z.
Int J Med Mushrooms. 2011;13(6):535-44.

Antioxidant activities of Ganoderma lucidum polysaccharides and their role on DNA damage in mice induced by cobalt-60 gamma-irradiation.
Zhao W, Jiang X, Deng W, Lai Y, Wu M, Zhang Z.
Food Chem Toxicol. 2012 Feb;50(2):303-9. Epub 2011 Nov 4.

Antioxidant activity and toxicity profile of total triterpenes isolated from Ganoderma lucidum (Fr.) P. Karst occurring in South India.
Smina TP, Mathew J, Janardhanan KK, Devasagayam TP.
Environ Toxicol Pharmacol. 2011 Nov;32(3):438-46. Epub 2011 Aug 30.

Environ Toxicol Pharmacol. 2011 Nov;32(3):438-46. Epub 2011 Aug 30.
Smina TP, De S, Devasagayam TP, Adhikari S, Janardhanan KK.
Mutat Res. 2011 Dec 24;726(2):188-94. Epub 2011 Sep 16.

Suppression of proliferation and oxidative stress by extracts of Ganoderma lucidum in the ovarian cancer cell line OVCAR-3.
Hsieh TC, Wu JM.
Int J Mol Med. 2011 Dec;28(6):1065-9. doi: 10.3892/ijmm.2011.788.

Ganoderma lucidum ameliorate mitochondrial damage in isoproterenol-induced myocardial infarction in rats by enhancing the activities of TCA cycle enzymes and respiratory chain complexes.
Sudheesh NP, Ajith TA, Janardhanan KK.
Int J Cardiol. 2011 Aug 22.

Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial.
Chu TT, Benzie IF, Lam CW, Fok BS, Lee KK, Tomlinson B.
Br J Nutr. 2011 Aug 1:1-11.

Ganoderma applanatum terpenes protect mouse liver against benzo(α)pyren-induced oxidative stress and inflammation.
Ma JQ, Liu CM, Qin ZH, Jiang JH, Sun YZ.
Environ Toxicol Pharmacol. 2011 May;31(3):460-8.

Polysaccharides purified from the submerged culture of Ganoderma formosanum stimulate macrophage activation and protect mice against Listeria monocytogenes infection.
Wang CL, Pi CC, Kuo CW, Zhuang YJ, Khoo KH, Liu WH, Chen CJ.
Biotechnol Lett. 2011 Nov;33(11):2271-8.

Evaluation of Selected Culinary-Medicinal Mushrooms for Antioxidant and ACE Inhibitory Activities.
Abdullah N, Ismail SM, Aminudin N, Shuib AS, Lau BF.
Evid Based Complement Alternat Med. 2012;2012:464238.

Effects of Ganoderma lucidum on obstructive jaundice-induced oxidative stress.
Aydin S, Aytac E, Uzun H, Altug T, Mansur B, Saygili S, Buyukpinarbasili N, Sariyar M.
Asian J Surg. 2010 Oct;33(4):173-80.

p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells.
Chen NH, Zhong JJ.
Phytomedicine. 2011 Jun 15;18(8-9):719-25. Epub 2011 Feb 25.

[Transformation of astragaloside IV in bidirectional solid fermenting of Astragalus membranaceus]
Ruan M, Zhang LY, Yu B, Chen YS, Zhuang Y.
Zhong Yao Cai. 2010 Mar;33(3):339-43.            

In vitro effects of plant and mushroom extracts on immunological function of chicken lymphocytes and macrophages.
Lee SH, Lillehoj HS, Hong YH, Jang SI, Lillehoj EP, Ionescu C, Mazuranok L, Bravo D.
Br Poult Sci. 2010 Apr;51(2):213-21.     

[Effect of Ganoderma lucidum polysaccharides on hemodynamic and antioxidation in T2DM rats]
Xue H, Qiao J, Meng G, Wu F, Luo J, Chen H, Zheng H, Xu J.
Zhongguo Zhong Yao Za Zhi. 2010 Feb;35(3):339-43.            

Ganoderma atrum polysaccharide protects cardiomyocytes against anoxia/reoxygenation-induced oxidative stress by mitochondrial pathway.
Li WJ, Nie SP, Chen Y, Xie MY, He M, Yu Q, Yan Y.
J Cell Biochem. 2010 May;110(1):191-200.     

Effects of sulfation on the physicochemical and functional properties of a water-insoluble polysaccharide preparation from Ganoderma lucidum.
Liu W, Wang H, Yao W, Gao X, Yu LL.
J Agric Food Chem. 2010 Mar 24;58(6):3336-41.     

Characterization and antioxidant activity of two low-molecular-weight polysaccharides purified from the fruiting bodies of Ganoderma lucidum.
Liu W, Wang H, Pang X, Yao W, Gao X.
Int J Biol Macromol. 2010 May 1;46(4):451-7.  

Medicinal mushroom Ganoderma lucidum (Leyss: Fr) Karst. triggers immunomodulatory effects and reduces nitric oxide synthesis in mice.
Rubel R, Dalla Santa HS, Bonatto SJ, Bello S, Fernandes LC, Di Bernardi R, Gern J, Santos CA, Soccol CR.
J Med Food. 2010 Feb;13(1):142-8.     

Therapeutic potential of Ganoderma lucidum (Fr.) P. Karst. against the declined antioxidant status in the mitochondria of post-mitotic tissues of aged mice.
Sudheesh NP, Ajith TA, Ramnath V, Janardhanan KK.
Clin Nutr. 2010 Jun;29(3):406-12.

Prevention of cisplatin induced nephrotoxicity by terpenes isolated from Ganoderma lucidum occurring in Southern Parts of India.
Pillai TG, John M, Sara Thomas G.
Exp Toxicol Pathol. 2009 Dec 2.

HPLC analysis of Ganoderma lucidum polysaccharides and its effect on antioxidant enzymes activity and Bax, Bcl-2 expression.
Yang Q, Wang S, Xie Y, Sun J, Wang J.
Int J Biol Macromol. 2010 Mar 1;46(2):167-72.   

Effects of mushroom-derived beta-glucan-rich polysaccharide extracts on nitric oxide production by bone marrow-derived macrophages and nuclear factor-kappaB transactivation in Caco-2 reporter cells: can effects be explained by structure?
Volman JJ, Helsper JP, Wei S, Baars JJ, van Griensven LJ, Sonnenberg AS, Mensink RP, Plat J.
Mol Nutr Food Res. 2010 Feb;54(2):268-76.

Ganodermasides A and B, two novel anti-aging ergosterols from spores of a medicinal mushroom Ganoderma lucidum on yeast via UTH1 gene.
Weng Y, Xiang L, Matsuura A, Zhang Y, Huang Q, Qi J.
Bioorg Med Chem. 2010 Feb;18(3):999-1002.

[Determination of the eliminating ratio of TCM polysaccharide to hydroxyl radical by kinetic fluorescent spectrophotometry]
Feng HP, Mo YY, Huang MS, Pan YQ, Fan HJ.
Zhong Yao Cai. 2009 Jul;32(7):1087-90.             : 19873737 [PubMed - indexed for MEDLINE]Related citations

Anticancer properties of Ganoderma lucidum methanol extracts in vitro and in vivo.
Harhaji Trajkovi LM, Mijatovi SA, Maksimovi -Ivani DD, Stojanovi ID, Momcilovi MB, Tufegdzi SJ, Maksimovi VM, Marjanovi ZS, Stosi -Grujici SD.
Nutr Cancer. 2009;61(5):696-707.

The protective effect of Ganoderma atrum polysaccharide against anoxia/reoxygenation injury in neonatal rat cardiomyocytes.
Li WJ, Nie SP, Yan Y, Zhu SB, Xie MY.
Life Sci. 2009 Oct 21;85(17-18):634-41.

Preparation, characterization, and antiproliferative activities of the Se-containing polysaccharide SeGLP-2B-1 from Se-enriched Ganoderma lucidum.
Shang D, Zhang J, Wen L, Li Y, Cui Q.
J Agric Food Chem. 2009 Sep 9;57(17):7737-42.

Isolating a cytoprotective compound from Ganoderma tsugae: effects on induction of Nrf-2-related genes in endothelial cells.
Wei YS, Wung BS, Lin YC, Hsieh CW.
Biosci Biotechnol Biochem. 2009 Aug;73(8):1757-63.

Triterpene-farnesyl hydroquinone conjugates from Ganoderma sinense.
Sato N, Ma CM, Komatsu K, Hattori M.
J Nat Prod. 2009 May 22;72(5):958-61.

Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged rat.
Sudheesh NP, Ajith TA, Janardhanan KK.
Biogerontology. 2009 Oct;10(5):627-36.

Free-radical scavenging and mitochondrial antioxidant activities of Reishi-Ganoderma lucidum (Curt: Fr) P. Karst and Arogyapacha-Trichopus zeylanicus Gaertn extracts.
Cherian E, Sudheesh NP, Janardhanan KK, Patani G.
J Basic Clin Physiol Pharmacol. 2009;20(4):289-307.

Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice.
Seto SW, Lam TY, Tam HL, Au AL, Chan SW, Wu JH, Yu PH, Leung GP, Ngai SM, Yeung JH, Leung PS, Lee SM, Kwan YW.
Phytomedicine. 2009 May;16(5):426-36.

Effect of Ganoderma lucidum on the activities of mitochondrial dehydrogenases and complex I and II of electron transport chain in the brain of aged rats.
Ajith TA, Sudheesh NP, Roshny D, Abishek G, Janardhanan KK.
Exp Gerontol. 2009 Mar;44(3):219-23.

A new class of natural glycopeptides with sugar moiety-dependent antioxidant activities derived from Ganoderma lucidum fruiting bodies.
Wu Y, Wang D.
J Proteome Res. 2009 Feb;8(2):436-42.

Ganoderma lucidum: a potent pharmacological macrofungus.
Sanodiya BS, Thakur GS, Baghel RK, Prasad GB, Bisen PS.
Curr Pharm Biotechnol. 2009 Dec;10(8):717-42.

Synergistic effect of laccase mediators on pentachlorophenol removal by Ganoderma lucidum laccase.
Jeon JR, Murugesan K, Kim YM, Kim EJ, Chang YS.
Appl Microbiol Biotechnol. 2008 Dec;81(4):783-90.

[Effects of cadmium stress on the antioxidative system in Ganoderma lucidum mycelia]
Wang SH, Zhang H, Cui YR, He QY, Zhang Q.
Ying Yong Sheng Tai Xue Bao. 2008 Jun;19(6):1355-61.

Selenium in edible mushrooms.
Falandysz J.
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2008 Jul-Sep;26(3):256-99.

Supplementation of methionine enhanced the ergothioneine accumulation in the Ganoderma neo-japonicum mycelia.
Lee WY, Park EJ, Ahn JK.
Appl Biochem Biotechnol. 2009 Jul;158(1):213-21.

Phenolic compound concentration and antioxidant activities of edible and medicinal mushrooms from Korea.
Kim MY, Seguin P, Ahn JK, Kim JJ, Chun SC, Kim EH, Seo SH, Kang EY, Kim SL, Park YJ, Ro HM, Chung IM.
J Agric Food Chem. 2008 Aug 27;56(16):7265-70.

The dual roles of Ganoderma antioxidants on urothelial cell DNA under carcinogenic attack.
Yuen JW, Gohel MD.
J Ethnopharmacol. 2008 Jul 23;118(2):324-30.  

Hepatoprotective effects of Ganoderma lucidum peptides against D-galactosamine-induced liver injury in mice.
Shi Y, Sun J, He H, Guo H, Zhang S.
J Ethnopharmacol. 2008 May 22;117(3):415-9.

Induction of premature senescence in human lung cancer by fungal immunomodulatory protein from Ganoderma tsugae.
Liao CH, Hsiao YM, Lin CH, Yeh CS, Wang JC, Ni CH, Hsu CP, Ko JL.
Food Chem Toxicol. 2008 May;46(5):1851-9.

Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum.
Lai CS, Yu MS, Yuen WH, So KF, Zee SY, Chang RC.
Brain Res. 2008 Jan 23;1190:215-24.

Indian medicinal mushrooms as a source of antioxidant and antitumor agents.
A Ajith T, K Janardhanan K.
J Clin Biochem Nutr. 2007 May;40(3):157-62. 

Molecular cloning and expression of a laccase from Ganoderma lucidum, and its antioxidative properties.
Joo SS, Ryu IW, Park JK, Yoo YM, Lee DH, Hwang KW, Choi HT, Lim CJ, Lee do I, Kim K.
Mol Cells. 2008 Feb 29;25(1):112-8.

Effect of Ganoderma lucidum on cytokine release by peritoneal macrophages.
Ahmadi K, Riazipour M.
Iran J Immunol. 2007 Dec;4(4):220-6.

Biodegradation of endocrine-disrupting bisphenol A by white rot fungus Irpex lacteus.
Shin EH, Choi HT, Song HG.
J Microbiol Biotechnol. 2007 Jul;17(7):1147-51. 

Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial.
Li EK, Tam LS, Wong CK, Li WC, Lam CW, Wachtel-Galor S, Benzie IF, Bao YX, Leung PC, Tomlinson B.
Arthritis Rheum. 2007 Oct 15;57(7):1143-50. 

Biological properties of different protein extracts from selenium-enriched Ganoderma lucidum.
Du M, Wang C, Hu XS, Zhao GH.
Int J Food Sci Nutr. 2008 Mar;59(2):134-47. 

Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats.
Wang X, Zhao X, Li D, Lou YQ, Lin ZB, Zhang GL.
Biol Pharm Bull. 2007 Sep;30(9):1702-6. 

Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease.
Chen LW, Wang YQ, Wei LC, Shi M, Chan YS.
CNS Neurol Disord Drug Targets. 2007 Aug;6(4):273-81.

Antioxidant small phenolic ingredients in Inonotus obliquus (persoon) Pilat (Chaga).
Nakajima Y, Sato Y, Konishi T.
Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1222-6.

Immunomodulation of RAW264.7 macrophages by GLIS, a proteopolysaccharide from Ganoderma lucidum.
Ji Z, Tang Q, Zhang J, Yang Y, Jia W, Pan Y.
J Ethnopharmacol. 2007 Jul 25;112(3):445-50.

Enhancement of ATP generation capacity, antioxidant activity and immunomodulatory activities by Chinese Yang and Yin tonifying herbs.
Ko KM, Leung HY.
Chin Med. 2007 Mar 27;2:3.     

Salidroside production by hairy roots of Rhodiola sachalinensis obtained after transformation with Agrobacterium rhizogenes.
Zhou X, Wu Y, Wang X, Liu B, Xu H.
Biol Pharm Bull. 2007 Mar;30(3):439-42. 

Effect of polysaccharides from Ganoderma lucidum on streptozotocin-induced diabetic nephropathy in mice.
He CY, Li WD, Guo SX, Lin SQ, Lin ZB.
J Asian Nat Prod Res. 2006 Dec;8(8):705-11. 

[The pharmacological study of Ganoderma spores and their active components]
Lin ZB, Wang PY.
Beijing Da Xue Xue Bao. 2006 Oct 18;38(5):541-7.

Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion.
Thyagarajan A, Jiang J, Hopf A, Adamec J, Sliva D.
Int J Mol Med. 2006 Oct;18(4):657-64. 

Antimutagenic activity of methanolic extract of Ganoderma lucidum and its effect on hepatic damage caused by benzo[a]pyrene.
Lakshmi B, Ajith TA, Jose N, Janardhanan KK.
J Ethnopharmacol. 2006 Sep 19;107(2):297-303.

Ganoderma lucidum extract inhibits proliferation of SW 480 human colorectal cancer cells.
Xie JT, Wang CZ, Wicks S, Yin JJ, Kong J, Li J, Li YC, Yuan CS.
Exp Oncol. 2006 Mar;28(1):25-9. 

In vitro and in vivo protective effects of proteoglycan isolated from mycelia of Ganoderma lucidum on carbon tetrachloride-induced liver injury.
Yang XJ, Liu J, Ye LB, Yang F, Ye L, Gao JR, Wu ZH.
World J Gastroenterol. 2006 Mar 7;12(9):1379-85. 

Ganoderma tsugae supplementation alleviates bronchoalveolar inflammation in an airway sensitization and challenge mouse model.
Lin JY, Chen ML, Chiang BL, Lin BF.
Int Immunopharmacol. 2006 Feb;6(2):241-51.

Ganoderma lucidum inhibits inducible nitric oxide synthase expression in macrophages.
Woo CW, Man RY, Siow YL, Choy PC, Wan EW, Lau CS, O K.
Mol Cell Biochem. 2005 Jul;275(1-2):165-71. 

Antimicrobial, cytotoxic and antioxidant activity of selected basidiomycetes from Yemen.
Al-Fatimi M, Wurster M, Kreisel H, Lindequist U.
Pharmazie. 2005 Oct;60(10):776-80. 

Antioxidant and nitric oxide synthase activation properties of Ganoderma applanatum.
Acharya K, Yonzone P, Rai M, Rupa A.
Indian J Exp Biol. 2005 Oct;43(10):926-9. 

Effect of Ganoderma lucidum on the quality and functionality of Korean traditional rice wine, yakju.
Kim JH, Lee DH, Lee SH, Choi SY, Lee JS.
J Biosci Bioeng. 2004;97(1):24-8. 

Ganoderma lucidum mycelia enhance innate immunity by activating NF-kappaB.
Kuo MC, Weng CY, Ha CL, Wu MJ.
J Ethnopharmacol. 2006 Jan 16;103(2):217-22.

Effect of Ganoderma lucidum on human DNA is dose dependent and mediated by hydrogen peroxide.
Wachtel-Galor S, Choi SW, Benzie IF.
Redox Rep. 2005;10(3):145-9.

Manganese superoxide dismutase in pathogenic fungi: an issue with pathophysiological and phylogenetic involvements.
Fréalle E, Noël C, Viscogliosi E, Camus D, Dei-Cas E, Delhaes L.
FEMS Immunol Med Microbiol. 2005 Sep 1;45(3):411-22.

Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum, in mice.
Gao Y, Gao H, Chan E, Tang W, Xu A, Yang H, Huang M, Lan J, Li X, Duan W, Xu C, Zhou S.
Immunol Invest. 2005;34(2):171-98. 

Formulation and in vitro/in vivo evaluation of combining DNA repair and immune enhancing nutritional supplements.
Pero RW, Amiri A, Sheng Y, Welther M, Rich M.
Phytomedicine. 2005 Apr;12(4):255-63.

New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants.
Kimura Y.
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Antioxidant activity of Ganoderma lucidum in acute ethanol-induced heart toxicity.
Wong KL, Chao HH, Chan P, Chang LP, Liu CF.
Phytother Res. 2004 Dec;18(12):1024-6.

Ganoderma total sterol (GS) and GS1 protect rat cerebral cortical neurons from hypoxia/reoxygenation injury.
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Life Sci. 2005 Jan 14;76(9):1027-37.

Novel antioxidant peptides from fermented mushroom Ganoderma lucidum.
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J Agric Food Chem. 2004 Oct 20;52(21):6646-52. 

Polysaccharide extract isolated from ganoderma lucidum protects rat cerebral cortical neurons from hypoxia/reoxygenation injury.
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J Pharmacol Sci. 2004 Jun;95(2):294-8. 

[Activation of mouse macrophages by the alkali-extracted polysaccharide from spore of Ganoderma lucidum]
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J Agric Food Chem. 2004 Jun 16;52(12):3954-9. 

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J Nat Prod. 2004 Feb;67(2):300-10.

Ganoderma lucidum ("Lingzhi"), a Chinese medicinal mushroom: biomarker responses in a controlled human supplementation study.
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Br J Nutr. 2004 Feb;91(2):263-9. 

Treatment of glomerular endothelial dysfunction in steroid-resistant nephrosis with Ganoderma lucidum, vitamins C, E and vasodilators.
Futrakul N, Boonyen M, Patumraj S, Siriviriyakul P, Tosukhowong P, Futrakul P.
Clin Hemorheol Microcirc. 2003;29(3-4):205-10. 

Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum.
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J Ethnopharmacol. 2004 Jan;90(1):17-20.

Ganoderma lucidum ('Lingzhi'); acute and short-term biomarker response to supplementation.
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In vitro analysis of the properties of Beiqishen tea.
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Nutrition. 2003 Oct;19(10):869-75.

In vitro and in vivo protective effect of Ganoderma lucidum polysaccharides on alloxan-induced pancreatic islets damage.
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Assessment of membrane protection by traditional Chinese medicines using a flow cytometric technique: preliminary findings.
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Protective effects of Ganoderma lucidum polysaccharides peptide on injury of macrophages induced by reactive oxygen species.
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Acta Pharmacol Sin. 2002 Sep;23(9):787-91. 

Hepatoprotective role of Ganoderma lucidum polysaccharide against BCG-induced immune liver injury in mice.
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World J Gastroenterol. 2002 Aug;8(4):728-33. 

Polysaccharide purified from Ganoderma lucidum inhibits spontaneous and Fas-mediated apoptosis in human neutrophils through activation of the phosphatidylinositol 3 kinase/Akt signaling pathway.
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J Leukoc Biol. 2002 Jul;72(1):207-16. 

Evaluation of the hepatic and renal-protective effects of Ganoderma lucidum in mice.
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Am J Chin Med. 2001;29(3-4):501-7. 

Inhibition of lipid peroxidation and oxidative DNA damage by Ganoderma lucidum.
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Phytother Res. 2001 May;15(3):245-9. 

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Ganoderma lucidum extract protects DNA from strand breakage caused by hydroxyl radical and UV irradiation.
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Int J Mol Med. 1999 Sep;4(3):273-7. 

Purification and characterization of manganese superoxide dismutase from Ganoderma microsporum.
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Biochem Mol Biol Int. 1997 Aug;42(5):1035-43. 

Antifibrotic effects of a polysaccharide extracted from Ganoderma lucidum, glycyrrhizin, and pentoxifylline in rats with cirrhosis induced by biliary obstruction.
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Radical scavenger and antihepatotoxic activity of Ganoderma formosanum, Ganoderma lucidum and Ganoderma neo-japonicum.
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Ganoderma atrum polysaccharide attenuates oxidative stress induced by d-galactose in mouse brain.
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GLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response.
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Medicinal and edible lignicolous fungi as natural sources of antioxidative and antibacterial agents.
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