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Two new triterpenoids from fruiting bodies of fungus Ganoderma lucidum.
Zhao ZZ, Yin RH, Chen HP, Feng T, Li ZH, Dong ZJ, Cui BK, Liu JK
J Asian Nat Prod Res. 2015 Jan 29:1-6.[Epub ahead of print]

Ganoderma lucidum for Cancer Treatment: We Are Close but Still Not There.
Cheng S, Sliva D.
Integr Cancer Ther. 2015 Jan 27. pii: 1534735414568721. [Epub ahead of print] Review.

Cytokine production suppression by culture supernatant of B16F10 cells and amelioration by Ganoderma lucidum polysaccharides in activated lymphocytes.
Cheng S, Sliva D.
Integr Cancer Ther. 2015 Jan 27. pii: 1534735414568721. [Epub ahead of print] Review.

Khz (Fusion Product of Ganoderma lucidum and Polyporus umbellatus Mycelia) Induces Apoptosis in Human Colon Carcinoma HCT116 Cells, Accompanied by an Increase in Reactive Oxygen Species, Activation of Caspase 3, and Increased Intracellular Ca(2+).
Kim TH, Kim JS, Kim ZH, Huang RB, Chae YL, Wang RS.
J Med Food. 2015 Mar;18(3):332-6. doi: 10.1089/jmf.2013.3135. Epub 2014 Dec 9.

Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities.
Ferreira IC, Heleno SA, Reis FS, Stojkovic D, Queiroz MJ, Vasconcelos MH, Sokovic M.
Phytochemistry. 2014 Nov 5. pii: S0031-9422(14)00415-4. doi: 10.1016/j.phytochem.2014.10.011. [Epub ahead of print] Review.

Ganoderma lucidum inhibits proliferation of human ovarian cancer cells by suppressing VEGF expression and up-regulating the expression of connexin 43.
Dai S, Liu J, Sun X, Wang N.
BMC Complement Altern Med. 2014 Nov 5;14:434. doi: 10.1186/1472-6882-14-434.

A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp.
Xia Q, Zhang H, Sun X, Zhao H, Wu L, Zhu D, Yang G, Shao Y, Zhang X, Mao X, Zhang L, She G.
Molecules. 2014 Oct 30;19(11):17478-535. doi: 10.3390/molecules191117478.

Fungal beta glucan protects radiation induced DNA damage in human lymphocytes.
Pillai TG, Maurya DK, Salvi VP, Janardhanan KK, Nair CK.
Ann Transl Med. 2014 Feb;2(2):13. doi: 10.3978/j.issn.2305-5839.2014.02.02.

Wound healing activity of an aqueous extract of the Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes).
Gupta A, Kirar V, Keshri GK, Gola S, Yadav A, Negi PS, Misra K.
Int J Med Mushrooms. 2014;16(4):345-54.

CARI III inhibits tumor growth in a melanoma-bearing mouse model through induction of G0/G1 cell cycle arrest.
Park HJ.
Molecules. 2014 Sep 12;19(9):14383-95. doi: 10.3390/molecules190914383.

A comparative study on immunomodulatory activity of polysaccharides from two official species of Ganoderma (Lingzhi).
Meng LZ, Xie J, Lv GP, Hu DJ, Zhao J, Duan JA, Li SP.
Nutr Cancer. 2014;66(7):1124-31. doi: 10.1080/01635581.2014.948215. Epub 2014 Sep 10.

Activation of antitumor immune responses by Ganoderma formosanum polysaccharides in tumor-bearing mice.
Wang CL, Lu CY, Hsueh YC, Liu WH, Chen CJ.
Appl Microbiol Biotechnol. 2014 Nov;98(22):9389-98. doi: 10.1007/s00253-014-6027-6. Epub 2014 Sep 2.

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential.
Wong KL, Wong RN, Zhang L, Liu WK, Ng TB, Shaw PC, Kwok PC, Lai YM, Zhang ZJ, Zhang Y, Tong Y, Cheung HP, Lu J, Sze SC.
Chin Med. 2014 Jul 19;9:19. doi: 10.1186/1749-8546-9-19. eCollection 2014. Review.

Khz-cp (crude polysaccharide extract obtained from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating P38 and NADPH oxidase-dependent generation of reactive oxygen species in SNU-1 cells.
Wong KL, Wong RN, Zhang L, Liu WK, Ng TB, Shaw PC, Kwok PC, Lai YM, Zhang ZJ, Zhang Y, Tong Y, Cheung HP, Lu J, Sze SC.
Chin Med. 2014 Jul 19;9:19. doi: 10.1186/1749-8546-9-19. eCollection 2014. Review.

A chemically sulfated polysaccharide derived from Ganoderma lucidum induces mitochondrial-mediated apoptosis in human osteosarcoma MG63 cells.
Sun Z, Huang K, Fu X, Zhou Z, Cui Y, Li H.
Tumour Biol. 2014 Oct;35(10):9919-26. doi: 10.1007/s13277-014-2217-1. Epub 2014 Jul 6.

Inhibitory activity of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (higher Basidiomycetes) on transformed cells by human papillomavirus.
Hernández-Márquez E, Lagunas-Martínez A, Bermudez-Morales VH, Burgete-García AI, León-Rivera I, Montiel-Arcos E, García-Villa E, Gariglio P, Madrid-Marina V V, Ondarza-Vidaurreta RN.
Int J Med Mushrooms. 2014;16(2):179-87.

A green chemistry approach for synthesizing biocompatible gold nanoparticles.
Gurunathan S, Han J, Park JH, Kim JH.
Nanoscale Res Lett. 2014 May 21;9(1):248. doi: 10.1186/1556-276X-9-248. eCollection 2014.

Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Liang Z, Guo YT, Yi YJ, Wang RC, Hu QL, Xiong XY.
Asian Pac J Cancer Prev. 2014;15(9):3981-6.

Clinical characteristics of gynecologic cancer patients who respond to salvage treatment with Lingzhi.
Suprasert P, Apichartpiyakul C, Sakonwasun C, Nitisuwanraksa P, Phuackchantuck R.
Asian Pac J Cancer Prev. 2014;15(10):4193-6.

FIP-gts potentiate autophagic cell death against cisplatin-resistant urothelial cancer cells.
Li JR, Cheng CL, Yang WJ, Yang CR, Ou YC, Wu MJ, Ko JL.
Anticancer Res. 2014 Jun;34(6):2973-83.

A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle.
Oliveira M, Reis FS, Sousa D, Tavares C, Lima RT, Ferreira IC, dos Santos T, Vasconcelos MH.
Food Funct. 2014 Jul 25;5(7):1389-94. doi: 10.1039/c4fo00258j.

Biological activity of Ganoderma lucidum basidiocarps cultivated on alternative and commercial substrate.
Cilerd?i? J, Vukojevi? J, Staji? M, Stanojkovi? T, Glamo?lija J.
J Ethnopharmacol. 2014 Aug 8;155(1):312-9. doi: 10.1016/j.jep.2014.05.036. Epub 2014 May 29.

Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
Liang Z, Yi Y, Guo Y, Wang R, Hu Q, Xiong X.
Int J Mol Sci. 2014 May 22;15(5):9103-16. doi: 10.3390/ijms15059103.

The effect of Cordyceps extract and a mixture of Ganoderma lucidum/Agaricus Blazi Murill extract on human endometrial cancer cell lines in vitro.
Hahne JC, Meyer SR, Dietl J, Honig A.
Int J Oncol. 2014 Jul;45(1):373-82. doi: 10.3892/ijo.2014.2414. Epub 2014 May 5.

An in vitro evaluation of graphene oxide reduced by Ganoderma spp. in human breast cancer cells (MDA-MB-231).
Gurunathan S, Han J, Park JH, Kim JH.
Int J Nanomedicine. 2014 Apr 8;9:1783-97. doi: 10.2147/IJN.S57735. eCollection 2014.

The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes.
Loganathan J, Jiang J, Smith A, Jedinak A, Thyagarajan-Sahu A, Sandusky GE, Nakshatri H, Sliva D.
Int J Oncol. 2014 Jun;44(6):2009-15. doi: 10.3892/ijo.2014.2375. Epub 2014 Apr 9.

The multifaceted effects of polysaccharides isolated from Dendrobium huoshanense on immune functions with the induction of interleukin-1 receptor antagonist (IL-1ra) in monocytes.
Lin J, Chang YJ, Yang WB, Yu AL, Wong CH.
PLoS One. 2014 Apr 4;9(4):e94040. doi: 10.1371/journal.pone.0094040. eCollection 2014.

Ganoderma atrum polysaccharide evokes antitumor activity via cAMP-PKA mediated apoptotic pathway and down-regulation of Ca(2+)/PKC signal pathway.
Zhang S, Nie S, Huang D, Huang J, Feng Y, Xie M.
Food Chem Toxicol. 2014 Jun;68:239-46. doi: 10.1016/j.fct.2014.03.020. Epub 2014 Apr 2.

A novel polysaccharide from Ganoderma atrum exerts antitumor activity by activating mitochondria-mediated apoptotic pathway and boosting the immune system.
Zhang S, Nie S, Huang D, Feng Y, Xie M.
J Agric Food Chem. 2014 Feb 19;62(7):1581-9. doi: 10.1021/jf4053012. Epub 2014 Feb 7.

Cytokine production suppression by culture supernatant of B16F10 cells and amelioration by Ganoderma lucidum polysaccharides in activated lymphocytes.
Sun LX, Li WD, Lin ZB, Duan XS, Xing EH, Jiang MM, Yang N, Qi HH, Sun Y, Li M, Niu YD, Lu J.
Cell Tissue Res. 2015 Jan 15. [Epub ahead of print]

A high throughput colorimetric assay of β-1,3-D-glucans by Congo red dye.
Semedo MC, Karmali A, Fonseca L.
J Microbiol Methods. 2015 Feb;109:140-8. doi: 10.1016/j.mimet.2014.12.020. Epub 2014 Dec 31.

Toll-like receptor 4 mediates the antitumor host response induced by Ganoderma atrum polysaccharide.
Yu Q, Nie SP, Wang JQ, Huang DF, Li WJ, Xie MY.
J Agric Food Chem. 2015 Jan 21;63(2):517-25. doi: 10.1021/jf5041096. Epub 2015 Jan 9.

Ganoderma lucidum polysaccharide exerts anti-tumor activity via MAPK pathways in HL-60 acute leukemia cells.
Yang G, Yang L, Zhuang Y, Qian X, Shen Y.
J Recept Signal Transduct Res. 2014 Oct 20:1-8. [Epub ahead of print]

Neuroprotective effect of pretreatment with ganoderma lucidum in cerebral ischemia/reperfusion injury in rat hippocampus.
Zhang W, Zhang Q, Deng W, Li Y, Xing G, Shi X, Du Y.
Neural Regen Res. 2014 Aug 1;9(15):1446-52. doi: 10.4103/1673-5374.139461.

Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells.
Choi S, Nguyen VT, Tae N, Lee S, Ryoo S, Min BS, Lee JH.
Toxicol Appl Pharmacol. 2014 Nov 1;280(3):434-42. doi: 10.1016/j.taap.2014.09.007. Epub 2014 Sep 16.

A polysaccharide from Ganoderma atrum inhibits tumor growth by induction of apoptosis and activation of immune response in CT26-bearing mice.
Zhang S, Nie S, Huang D, Huang J, Feng Y, Xie M.
J Agric Food Chem. 2014 Sep 24;62(38):9296-304. doi: 10.1021/jf503250d. Epub 2014 Sep 11.

Exopolysaccharide from Ganoderma applanatum as a promising bioactive compound with cytostatic and antibacterial properties.
Osińska-Jaroszuk M, Jaszek M, Mizerska-Dudka M, B?achowicz A, Rejczak TP, Janusz G, Wydrych J, Polak J, Jarosz-Wilko?azka A, Kandefer-Szerszeń M.
Biomed Res Int. 2014;2014:743812. doi: 10.1155/2014/743812. Epub 2014 Jul 10.

Submerged cultivation of Ganoderma lucidum and the effects of its polysaccharides on the production of human cytokines TNF-α, IL-12, IFN-γ, IL-2, IL-4, IL-10 and IL-17.
Habijanic J, Berovic M, Boh B, Plankl M, Wraber B.
N Biotechnol. 2015 Jan 25;32(1):85-95. doi: 10.1016/j.nbt.2014.07.007. Epub 2014 Jul 29.

Khz-cp (crude polysaccharide extract obtained from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating P38 and NADPH oxidase-dependent generation of reactive oxygen species in SNU-1 cells.
Kim TH, Kim JS, Kim ZH, Huang RB, Chae YL, Wang RS.
BMC Complement Altern Med. 2014 Jul 10;14:236. doi: 10.1186/1472-6882-14-236.

Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection.
Zhang W, Tao J, Yang X, Yang Z, Zhang L, Liu H, Wu K, Wu J.
Biochem Biophys Res Commun. 2014 Jul 4;449(3):307-12. doi: 10.1016/j.bbrc.2014.05.019. Epub 2014 May 15.

The Effect of Mushroom Beta-Glucans from Solid Culture of Ganoderma lucidum on Inhibition of the Primary Tumor Metastasis.
Chen SN, Chang CS, Hung MH, Chen S, Wang W, Tai CJ, Lu CL.
Evid Based Complement Alternat Med. 2014;2014:252171. doi: 10.1155/2014/252171. Epub 2014 Apr 1.

Production and functional characterization of a novel fungal immunomodulatory protein FIP-SN15 shuffled from two genes of Ganoderma species.
Cong WR, Xu H, Liu Y, Li QZ, Li W, Zhou XW.
Appl Microbiol Biotechnol. 2014 Jul;98(13):5967-75. doi: 10.1007/s00253-014-5539-4. Epub 2014 Feb 28.

Suppression of the production of transforming growth factor β1, interleukin-10, and vascular endothelial growth factor in the B16F10 cells by Ganoderma lucidum polysaccharides.
Sun LX, Lin ZB, Duan XS, Qi HH, Yang N, Li M, Xing EH, Sun Y, Yu M, Li WD, Lu J.
J Interferon Cytokine Res. 2014 Sep;34(9):667-75. doi: 10.1089/jir.2012.0101. Epub 2014 Mar 27.

Effects of Selenium-Enriched Protein from Ganoderma lucidum on the Levels of IL-1 β and TNF- α , Oxidative Stress, and NF- κ B Activation in Ovalbumin-Induced Asthmatic Mice.
Min-Chang G, Wei-Hong T, Zhen X, Jie S.
Evid Based Complement Alternat Med. 2014;2014:182817. doi: 10.1155/2014/182817. Epub 2014 Feb 10.

Acetylation and carboxymethylation of the polysaccharide from Ganoderma atrum and their antioxidant and immunomodulating activities.
Chen Y, Zhang H, Wang Y, Nie S, Li C, Xie M.
Food Chem. 2014 Aug 1;156:279-88. doi: 10.1016/j.foodchem.2014.01.111. Epub 2014 Feb 7.

Immunomodulatory of selenium nano-particles decorated by sulfated Ganoderma lucidum polysaccharides.
Wang J, Zhang Y, Yuan Y, Yue T.
Food Chem Toxicol. 2014 Jun;68:183-9. doi: 10.1016/j.fct.2014.03.003. Epub 2014 Mar 10.

Anti-inflammatory and hepatoprotective effects of Ganoderma lucidum polysaccharides on carbon tetrachloride-induced hepatocyte damage in common carp (Cyprinus carpio L.).
Liu YJ, Du JL, Cao LP, Jia R, Shen YJ, Zhao CY, Xu P, Yin GJ.
Int Immunopharmacol. 2015 Mar;25(1):112-20. doi: 10.1016/j.intimp.2015.01.023. Epub 2015 Jan 29.

Ganoderma formosanum polysaccharides attenuate Th2 inflammation and airway hyperresponsiveness in a murine model of allergic asthma.
Pi CC, Wang HY, Lu CY, Lu FL, Chen CJ.
Springerplus. 2014 Jun 12;3:297. doi: 10.1186/2193-1801-3-297. eCollection 2014.

Inflammatory modulation effect of glycopeptide from Ganoderma capense (Lloyd) Teng.
Zhou Y, Chen S, Ding R, Yao W, Gao X.
Mediators Inflamm. 2014;2014:691285. doi: 10.1155/2014/691285. Epub 2014 May 22.

Suppression of inflammatory and allergic responses by pharmacologically potent fungus Ganoderma lucidum.
Bhardwaj N, Katyal P, Sharma AK.
Recent Pat Inflamm Allergy Drug Discov. 2014;8(2):104-17.

Extraction of polysaccharide from Ganoderma lucidum and its immune enhancement activity.
Huang SQ, Ning ZX.
Int J Biol Macromol. 2010 Oct 1;47(3):336-41.

GLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response.
Zhang J, Tang Q, Zhou C, Jia W, Da Silva L, Nguyen LD, Reutter W, Fan H.
Life Sci. 2010 Sep 30.

Preparation, characterisation and anti-tumour activity of Ganoderma lucidum polysaccharide nanoparticles.
Li N, Hu YL, He CX, Hu CJ, Zhou J, Tang GP, Gao JQ.
J Pharm Pharmacol. 2010 Jan;62(1):139-44.

Polysaccharides PS-G and protein LZ-8 from Reishi (Ganoderma lucidum) exhibit diverse functions in regulating murine macrophages and T lymphocytes.
Yeh CH, Chen HC, Yang JJ, Chuang WI, Sheu F.
J Agric Food Chem. 2010 Aug 11;58(15):8535-44.

Induction of apoptosis by ethanol extracts of Ganoderma lucidum in human gastric carcinoma cells.
Jang KJ, Han MH, Lee BH, Kim BW, Kim CH, Yoon HM, Choi YH.
J Acupunct Meridian Stud. 2010 Mar;3(1):24-31.

The effects of two different ganoderma species (Lingzhi) on gene expression in human monocytic THP-1 cells.
Cheng CH, Leung AY, Chen CF.
Nutr Cancer. 2010 Jul;62(5):648-58.

Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK).
Thyagarajan A, Jedinak A, Nguyen H, Terry C, Baldridge LA, Jiang J, Sliva D.
Nutr Cancer. 2010 Jul;62(5):630-40.

A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas.
Oka S, Tanaka S, Yoshida S, Hiyama T, Ueno Y, Ito M, Kitadai Y, Yoshihara M, Chayama K.
Hiroshima J Med Sci. 2010 Mar;59(1):1-6.

Optimization of alkaline extraction of polysaccharides from Ganoderma lucidum and their effect on immune function in mice.
Huang SQ, Li JW, Wang Z, Pan HX, Chen JX, Ning ZX.
Molecules. 2010 May 25;15(5):3694-708.

In vitro effects of plant and mushroom extracts on immunological function of chicken lymphocytes and macrophages.
Lee SH, Lillehoj HS, Hong YH, Jang SI, Lillehoj EP, Ionescu C, Mazuranok L, Bravo D.
Br Poult Sci. 2010 Apr;51(2):213-21.

The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis.
Weng CJ, Yen GC.
Clin Exp Metastasis. 2010 May;27(5):361-9.

Medical mushrooms used for biochemical failure after radical treatment for prostate cancer: an open-label study.
Yoshimura K, Kamoto T, Ogawa O, Matsui S, Tsuchiya N, Tada H, Murata K, Yoshimura K, Habuchi T, Fukushima M.
Int J Urol. 2010 Jun;17(6):548-54.

Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Chen NH, Liu JW, Zhong JJ.
Pharmacol Rep. 2010 Jan-Feb;62(1):150-63.

Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis.
Ferretti R, Palumbo V, Di Savino A, Velasco S, Sbroggiò M, Sportoletti P, Micale L, Turco E, Silengo L, Palumbo G, Hirsch E, Teruya-Feldstein J, Bonaccorsi S, Pandolfi PP, Gatti M, Tarone G, Brancaccio M.
Dev Cell. 2010 Mar 16;18(3):486-95.

Cytokines expression induced by Ganoderma sinensis fungal immunomodulatory proteins (FIP-gsi) in mouse spleen cells.
Li Q, Wang X, Chen Y, Lin J, Zhou X.
Appl Biochem Biotechnol. 2010 Nov;162(5):1403-13.

Medicinal mushroom Ganoderma lucidum (Leyss: Fr) Karst. triggers immunomodulatory effects and reduces nitric oxide synthesis in mice.
Rubel R, Dalla Santa HS, Bonatto SJ, Bello S, Fernandes LC, Di Bernardi R, Gern J, Santos CA, Soccol CR.
J Med Food. 2010 Feb;13(1):142-8.

Ganoderma lucidum induced apoptosis in NB4 human leukemia cells: involvement of Akt and Erk.
Calviño E, Manjón JL, Sancho P, Tejedor MC, Herráez A, Diez JC.
J Ethnopharmacol. 2010 Mar 2;128(1):71-8.

Supplements for immune enhancement in hematologic malignancies.
Sze DM, Chan GC.
Hematology Am Soc Hematol Educ Program. 2009:313-9. Review.

Ganoderma lucidum extracts inhibited leukemia WEHI-3 cells in BALB/c mice and promoted an immune response in vivo.
Chang YH, Yang JS, Yang JL, Wu CL, Chang SJ, Lu KW, Lin JJ, Hsia TC, Lin YT, Ho CC, Wood WG, Chung JG.
Biosci Biotechnol Biochem. 2009 Dec;73(12):2589-94..

Effects of mushroom-derived beta-glucan-rich polysaccharide extracts on nitric oxide production by bone marrow-derived macrophages and nuclear factor-kappaB transactivation in Caco-2 reporter cells: can effects be explained by structure?
Volman JJ, Helsper JP, Wei S, Baars JJ, van Griensven LJ, Sonnenberg AS, Mensink RP, Plat J.
Mol Nutr Food Res. 2010 Feb;54(2):268-76.

Enhancement of antitumor activities in sulfated and carboxymethylated polysaccharides of Ganoderma lucidum.
Wang J, Zhang L, Yu Y, Cheung PC.
J Agric Food Chem. 2009 Nov 25;57(22):10565-72.

Profiling carbohydrate-receptor interaction with recombinant innate immunity receptor-Fc fusion proteins.
Hsu TL, Cheng SC, Yang WB, Chin SW, Chen BH, Huang MT, Hsieh SL, Wong CH.
J Biol Chem. 2009 Dec 11;284(50):34479-89.

An immunomodulatory protein, Ling Zhi-8, induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and MAPK pathways.
Lin YL, Liang YC, Tseng YS, Huang HY, Chou SY, Hseu RS, Huang CT, Chiang BL.
J Leukoc Biol. 2009 Oct;86(4):877-89.

The effect of a novel botanical agent TBS-101 on invasive prostate cancer in animal models.
Evans S, Dizeyi N, Abrahamsson PA, Persson J.
Anticancer Res. 2009 Oct;29(10):3917-24.

Anticancer properties of Ganoderma lucidum methanol extracts in vitro and in vivo.
Harhaji Trajkovi LM, Mijatovi SA, Maksimovi -Ivani DD, Stojanovi ID, Momcilovi MB, Tufegdzi SJ, Maksimovi VM, Marjanovi ZS, Stosi -Grujici SD.
Nutr Cancer. 2009;61(5):696-707.

[Effects of medicinal insect Catharsius molossus on submerged fermentation and in vivo anti-hepatoma activity of Ganoderma lucidum]
Liu G, Ding C, Zhang K, Wang X.
Sheng Wu Gong Cheng Xue Bao. 2009 Jun;25(6):880-6.

Complementary therapies, herbs, and other OTC agents: Reishi mushroom.
Cassileth B.
Oncology (Williston Park). 2009 Jul;23(8):728.

Enteric mucosal immune response might trigger the immunomodulation activity of Ganoderma lucidum polysaccharide in mice.
Zhao H, Luo Y, Lu C, Lin N, Xiao C, Guan S, Guo DA, Liu Z, Ju D, He X, Lu A.
Planta Med. 2010 Feb;76(3):223-7.

Ganoderma lucidum Polysaccharides Induce Macrophage-like Differentiation in Human Leukemia THP-1 Cells via Caspase and p53 Activation.
Hsu JW, Huang HC, Chen ST, Wong CH, Juan HF.
Evid Based Complement Alternat Med. 2009 Aug 20.

Preparation, characterization, and antiproliferative activities of the Se-containing polysaccharide SeGLP-2B-1 from Se-enriched Ganoderma lucidum.
Shang D, Zhang J, Wen L, Li Y, Cui Q.
J Agric Food Chem. 2009 Sep 9;57(17):7737-42.

Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum.
Dudhgaonkar S, Thyagarajan A, Sliva D.
Int Immunopharmacol. 2009 Oct;9(11):1272-80. .

Ganoderma lucidum immunomodulatory protein(Lz-8) expressed in Pichia pastoris and the identification of immunocompetence.
Liang C, Zhang S, Liu Z, Sun F.
Sheng Wu Gong Cheng Xue Bao. 2009 Mar;25(3):441-7.

Ganoderma lucidum Protects Dopaminergic Neuron Degeneration Through Inhibition of Microglial Activation.
Zhang R, Xu S, Cai Y, Zhou M, Zuo X, Chan P.
Evid Based Complement Alternat Med. 2009 Jul 16.

Ganoderma lucidum induces the expression of CD40/CD86 on peripheral blood monocytes.
Ahmadi K, Riazipour M.
Iran J Immunol. 2009 Jun;6(2):87-91.

Characterization and immunostimulatory activity of a polysaccharide from the spores of Ganoderma lucidum.
Guo L, Xie J, Ruan Y, Zhou L, Zhu H, Yun X, Jiang Y, Lü L, Chen K, Min Z, Wen Y, Gu J.
Int Immunopharmacol. 2009 Sep;9(10):1175-82.
[Effect of Ganoderma lucidum polysaccharides on intestinal mucosal immune system in H22 liver cancer bearing mice]
Zhou GQ, Zhao HY, Lu C.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Apr;29(4):335-9.

Cytotoxic activities of 9,11-dehydroergosterol peroxide and ergosterol peroxide from the fermentation mycelia of ganoderma lucidum cultivated in the medium containing leguminous plants on Hep 3B cells.
Chen YK, Kuo YH, Chiang BH, Lo JM, Sheen LY.
J Agric Food Chem. 2009 Jul 8;57(13):5713-9.

Inhibitory effects of ganoderma lucidum on tumorigenesis and metastasis of human hepatoma cells in cells and animal models.
Weng CJ, Chau CF, Yen GC, Liao JW, Chen DH, Chen KD.
J Agric Food Chem. 2009 Jun 10;57(11):5049-57.

Evaluation of antiproliferative activities and action mechanisms of extracts from two species of Ganoderma on tumor cell lines.
Liu YW, Gao JL, Guan J, Qian ZM, Feng K, Li SP.
J Agric Food Chem. 2009 Apr 22;57(8):3087-93.

Ganoderma tsugae extract inhibits expression of epidermal growth factor receptor and angiogenesis in human epidermoid carcinoma cells: In vitro and in vivo.
Hsu SC, Ou CC, Chuang TC, Li JW, Lee YJ, Wang V, Liu JY, Chen CS, Lin SC, Kao MC.
Cancer Lett. 2009 Aug 18;281(1):108-16.

Ganoderic acid DM: anti-androgenic osteoclastogenesis inhibitor.
Liu J, Shiono J, Shimizu K, Kukita A, Kukita T, Kondo R.
Bioorg Med Chem Lett. 2009 Apr 15;19(8):2154-7.

Anti-androgen effects of extracts and compounds from Ganoderma lucidum.
Liu J, Tamura S, Kurashiki K, Shimizu K, Noda K, Konishi F, Kumamoto S, Kondo R.
Chem Biodivers. 2009 Feb;6(2):231-43.

[Effects of Ganoderma lucidum spores on HepG2 cells proliferation and growth cycle]
Li L, Li T, Wang XJ, Xu JP, Wang SG.
Zhong Yao Cai. 2008 Oct;31(10):1514-8.

Effect of Ganoderma on drug-sensitive and multidrug-resistant small-cell lung carcinoma cells.
Sadava D, Still DW, Mudry RR, Kane SE.
Cancer Lett. 2009 May 18;277(2):182-9.

Effect of citronellol and the Chinese medical herb complex on cellular immunity of cancer patients receiving chemotherapy/radiotherapy.
Zhuang SR, Chen SL, Tsai JH, Huang CC, Wu TC, Liu WS, Tseng HC, Lee HS, Huang MC, Shane GT, Yang CH, Shen YC, Yan YY, Wang CK.
Phytother Res. 2009 Jun;23(6):785-90.

Lipid extract from completely sporoderm-broken germinating Ganoderma sinensis spores elicits potent antitumor immune responses in human macrophages.
Zhang JP, Zheng L, Wang JH, Magnusson KE, Liu X.
Phytother Res. 2009 Jun;23(6):844-50.

Pharmacological values of medicinal mushrooms for prostate cancer therapy: the case of Ganoderma lucidum.
Mahajna J, Dotan N, Zaidman BZ, Petrova RD, Wasser SP.
Nutr Cancer. 2009;61(1):16-26.

Therapeutic potential of various beta-glucan sources in conjunction with anti-tumor monoclonal antibody in cancer therapy.
Driscoll M, Hansen R, Ding C, Cramer DE, Yan J.
Cancer Biol Ther. 2009 Feb;8(3):218-25.

Regulation of osteoclastogenesis by ganoderic acid DM isolated from Ganoderma lucidum.
Miyamoto I, Liu J, Shimizu K, Sato M, Kukita A, Kukita T, Kondo R.
Eur J Pharmacol. 2009 Jan 5;602(1):1-7.

Chinese herbs (Astragalus radix and Ganoderma lucidum) enhance immune response of carp, Cyprinus carpio, and protection against Aeromonas hydrophila.
Yin G, Ardó L, Thompson KD, Adams A, Jeney Z, Jeney G.
Fish Shellfish Immunol. 2009 Jan;26(1):140-5.

Ganoderma tsugae extracts inhibit colorectal cancer cell growth via G(2)/M cell cycle arrest.
Hsu SC, Ou CC, Li JW, Chuang TC, Kuo HP, Liu JY, Chen CS, Lin SC, Su CH, Kao MC.
J Ethnopharmacol. 2008 Dec 8;120(3):394-401.

Ganoderic acid Me inhibits tumor invasion through down-regulating matrix metalloproteinases 2/9 gene expression.
Chen NH, Liu JW, Zhong JJ.
J Pharmacol Sci. 2008 Oct;108(2):212-6.

The signaling cascades of Ganoderma lucidum extracts in stimulating non-amyloidogenic protein secretion in human neuroblastoma SH-SY5Y cell lines.
Pinweha S, Wanikiat P, Sanvarinda Y, Supavilai P.
Neurosci Lett. 2008 Dec 19;448(1):62-6.

Possible involvement of long chain fatty acids in the spores of Ganoderma lucidum (Reishi Houshi) to its anti-tumor activity.
Fukuzawa M, Yamaguchi R, Hide I, Chen Z, Hirai Y, Sugimoto A, Yasuhara T, Nakata Y.
Biol Pharm Bull. 2008 Oct;31(10):1933-7.

Cytotoxic lanostanoid triterpenes from Ganoderma lucidum.
Guan SH, Xia JM, Yang M, Wang XM, Liu X, Guo DA.
J Asian Nat Prod Res. 2008 Jul-Aug;10(7-8):705-10.

Effect of Ganoderma lucidum capsules on T lymphocyte subsets in football players on "living high-training low".
Zhang Y, Lin Z, Hu Y, Wang F.
Br J Sports Med. 2008 Oct;42(10):819-22.

Serum amyloid A mediates the inhibitory effect of Ganoderma lucidum polysaccharides on tumor cell adhesion to endothelial cells.
Li YB, Wang R, Wu HL, Li YH, Zhong LJ, Yu HM, Li XJ.
Oncol Rep. 2008 Sep;20(3):549-56.

Immunomodulatory capacity of fungal proteins on the cytokine production of human peripheral blood mononuclear cells.
Jeurink PV, Noguera CL, Savelkoul HF, Wichers HJ.
Int Immunopharmacol. 2008 Aug;8(8):1124-33.

Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory function.
Chan WK, Cheung CC, Law HK, Lau YL, Chan GC.
J Hematol Oncol. 2008 Jul 21;1:9.

Toxicity of a traditional Chinese medicine, Ganoderma lucidum, in children with cancer.
Gill SK, Rieder MJ.
Can J Clin Pharmacol. 2008 Summer;15(2):e275-85.

Effects of the antlered form of Ganoderma lucidum on tumor growth and metastasis in cyclophosphamide-treated mice.
Nonaka Y, Ishibashi H, Nakai M, Shibata H, Kiso Y, Abe S.
Biosci Biotechnol Biochem. 2008 Jun;72(6):1399-408. Epub 2008 Jun 7.

Reishi immuno-modulation protein induces interleukin-2 expression via protein kinase-dependent signaling pathways within human T cells.
Hsu HY, Hua KF, Wu WC, Hsu J, Weng ST, Lin TL, Liu CY, Hseu RS, Huang CT.
J Cell Physiol. 2008 Apr;215(1):15-26.

Effects of fermentation products of Ganoderma lucidum on growth performance and immunocompetence in weanling pigs.
Chen SD, Hsieh MC, Chiou MT, Lai YS, Cheng YH.
Arch Anim Nutr. 2008 Feb;62(1):22-32.

[Preparation and biological properties of basidiomycete aqueous extracts and their mycelial compositions]
Bukhman VM, Treshchalina EM, Krasnopol'skaia LM, Isakova EB, Sedakova LA, Avtonomova AV, Leont'eva MI, Soboleva NIu, Belitski? IV, Bakanov AV.
Antibiot Khimioter. 2007;52(1-2):4-9.

Telomerase-associated apoptotic events by mushroom ganoderma lucidum on premalignant human urothelial cells.
Yuen JW, Gohel MD, Au DW.
Nutr Cancer. 2008;60(1):109-19.

Reversal effect of Ganoderma lucidum polysaccharide on multidrug resistance in K562/ADM cell line.
Li WD, Zhang BD, Wei R, Liu JH, Lin ZB.
Acta Pharmacol Sin. 2008 May;29(5):620-7.

Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling.
Jiang J, Grieb B, Thyagarajan A, Sliva D.
Int J Mol Med. 2008 May;21(5):577-84.

Ganoderma applanatum: a promising mushroom for antitumor and immunomodulating activity.
Jeong YT, Yang BK, Jeong SC, Kim SM, Song CH.
Phytother Res. 2008 May;22(5):614-9.

Induction of premature senescence in human lung cancer by fungal immunomodulatory protein from Ganoderma tsugae.
Liao CH, Hsiao YM, Lin CH, Yeh CS, Wang JC, Ni CH, Hsu CP, Ko JL.
Food Chem Toxicol. 2008 May;46(5):1851-9. Epub 2008 Feb 2.

[Changes of serum interferon-gamma levels in mice bearing S-180 tumor and the interventional effect of immunomodulators]
Li L, Lei LS, Yu CL.
Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jan;28(1):65-8.

Differential protein expression in mouse splenic mononuclear cells treated with polysaccharides from spores of Ganoderma lucidum.
Ma C, Guan SH, Yang M, Liu X, Guo DA.
Phytomedicine. 2008 Apr;15(4):268-76.

Extracellular expression of a functional recombinant Ganoderma lucidium immunomodulatory protein by Bacillus subtilis and Lactococcus lactis.
Yeh CM, Yeh CK, Hsu XY, Luo QM, Lin MY.
Appl Environ Microbiol. 2008 Feb;74(4):1039-49. .

Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1.
Weng CJ, Chau CF, Hsieh YS, Yang SF, Yen GC.
Carcinogenesis. 2008 Jan;29(1):147-56.

Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction.
Cheng KC, Huang HC, Chen JH, Hsu JW, Cheng HC, Ou CH, Yang WB, Chen ST, Wong CH, Juan HF.
BMC Genomics. 2007 Nov 9;8:411.

Potential of a novel polysaccharide preparation (GLPP) from Anhui-grown Ganoderma lucidum in tumor treatment and immunostimulation.
Pang X, Chen Z, Gao X, Liu W, Slavin M, Yao W, Yu LL.
J Food Sci. 2007 Aug;72(6):S435-42.

The immune effects of edible fungus polysaccharides compounds in mice.
Yin Y, Fu W, Fu M, He G, Traore L.
Asia Pac J Clin Nutr. 2007;16 Suppl 1:258-60.

The anti-invasive effect of lucidenic acids isolated from a new Ganoderma lucidum strain.
Weng CJ, Chau CF, Chen KD, Chen DH, Yen GC.
Mol Nutr Food Res. 2007 Dec;51(12):1472-7.

Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats.
Wang X, Zhao X, Li D, Lou YQ, Lin ZB, Zhang GL.
Biol Pharm Bull. 2007 Sep;30(9):1702-6.

Two new lanostanoids from Ganoderma resinaceum.
Niu XM, Li SH, Xiao WL, Sun HD, Che CT.
J Asian Nat Prod Res. 2007 Sep-Dec;9(6-8):659-64.

Human nonmetastatic clone 23 type 1 gene suppresses migration of cervical cancer cells and enhances the migration inhibition of fungal immunomodulatory protein from Ganoderma tsugae.
Wang PH, Yang SF, Chen GD, Han CP, Chen SC, Lin LY, Ko JL.
Reprod Sci. 2007 Jul;14(5):475-85.

Ganoderma lucidum and its pharmaceutically active compounds.
Boh B, Berovic M, Zhang J, Zhi-Bin L.
Biotechnol Annu Rev. 2007;13:265-301.

Androgen receptor-dependent and -independent mechanisms mediate Ganoderma lucidum activities in LNCaP prostate cancer cells.
Zaidman BZ, Wasser SP, Nevo E, Mahajna J.
Int J Oncol. 2007 Oct;31(4):959-67.

Nuclear translocation of telomerase reverse transcriptase and calcium signaling in repression of telomerase activity in human lung cancer cells by fungal immunomodulatory protein from Ganoderma tsugae.
Liao CH, Hsiao YM, Sheu GT, Chang JT, Wang PH, Wu MF, Shieh GJ, Hsu CP, Ko JL.
Biochem Pharmacol. 2007 Nov 15;74(10):1541-54.

Ganodermataceae: natural products and their related pharmacological functions.
Zhou X, Lin J, Yin Y, Zhao J, Sun X, Tang K.
Am J Chin Med. 2007;35(4):559-74. .

[Effect of Ganoderma lucidum polysaccharides on tumor cell nucleotide content and cell cycle in S180 ascitic tumor-bearing mice]
Li JJ, Lei LS, Yu CL, Zhu ZG, Zhang Q, Wu SG.
Nan Fang Yi Ke Da Xue Xue Bao. 2007 Jul;27(7):1003-5.

Antiinflammatory triterpenoids and steroids from Ganoderma lucidum and G. tsugae.
Ko HH, Hung CF, Wang JP, Lin CN.
Phytochemistry. 2008 Jan;69(1):234-9.

The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum.
Liu J, Shimizu K, Konishi F, Kumamoto S, Kondo R.
Bioorg Med Chem. 2007 Jul 15;15(14):4966-72.

Regression of gastric large B-Cell lymphoma accompanied by a florid lymphoma-like T-cell reaction: immunomodulatory effect of Ganoderma lucidum (Lingzhi)?
Cheuk W, Chan JK, Nuovo G, Chan MK, Fok M.
Int J Surg Pathol. 2007 Apr;15(2):180-6.

Enhancement of IL-2 and IFN-gamma expression and NK cells activity involved in the anti-tumor effect of ganoderic acid Me in vivo.
Wang G, Zhao J, Liu J, Huang Y, Zhong JJ, Tang W.
Int Immunopharmacol. 2007 Jun;7(6):864-70.

Coprinus comatus and Ganoderma lucidum interfere with androgen receptor function in LNCaP prostate cancer cells.
Zaidman BZ, Wasser SP, Nevo E, Mahajna J.
Mol Biol Rep. 2008 Jun;35(2):107-17.

Ganoderma lucidum: a cause of pseudoparasitosis.
Wanachiwanawin D, Piankijagum A, Chaiprasert A, Lertlaituan P, Tungtrongchitr A, Chinabutr P.
Southeast Asian J Trop Med Public Health. 2006 Nov;37(6):1099-102.

Combined effect of green tea and Ganoderma lucidum on invasive behavior of breast cancer cells.
Thyagarajan A, Zhu J, Sliva D.
Int J Oncol. 2007 Apr;30(4):963-9.

Enhancement of ATP generation capacity, antioxidant activity and immunomodulatory activities by Chinese Yang and Yin tonifying herbs.
Ko KM, Leung HY.
Chin Med. 2007 Mar 27;2:3.

Anti-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidum.
Akihisa T, Nakamura Y, Tagata M, Tokuda H, Yasukawa K, Uchiyama E, Suzuki T, Kimura Y.
Chem Biodivers. 2007 Feb;4(2):224-31.

Ganoderma lucidum polysaccharides enhance the function of immunological effector cells in immunosuppressed mice.
Zhu XL, Chen AF, Lin ZB.
J Ethnopharmacol. 2007 May 4;111(2):219-26.

[Antitumor activity of extracts of Ganoderma lucidum and their protective effects on damaged HL-7702 cells induced by radiotherapy and chemotherapy]
Wang DH, Weng XC.
Zhongguo Zhong Yao Za Zhi. 2006 Oct;31(19):1618-22.

Ganoderma tsugae in vivo modulates Th1/Th2 and macrophage responses in an allergic murine model.
Lin JY, Chen ML, Lin BF.
Food Chem Toxicol. 2006 Dec;44(12):2025-32.

Antiproliferative ability of a combination regimen of crocodile egg extract, wild radix ginseng and natural Ganoderma lucidum on acute myelogenous leukemia.
Chui CH, Wong RS, Cheng GY, Lau FY, Kok SH, Cheng CH, Cheung F, Tang WK, Teo IT, Chan AS, Tang JC.
Oncol Rep. 2006 Dec;16(6):1313-6.

Inhibitory effect of a water-soluble extract from the culture medium of Ganoderma lucidum (Rei-shi) mycelia on the development of pulmonary adenocarcinoma induced by N-nitrosobis (2-hydroxypropyl) amine in Wistar rats.
Kashimoto N, Hayama M, Kamiya K, Watanabe H.
Oncol Rep. 2006 Dec;16(6):1181-7.

Comparative studies of various ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitro.
Yue GG, Fung KP, Tse GM, Leung PC, Lau CB.
J Altern Complement Med. 2006 Oct;12(8):777-89.

Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells.
Tang W, Liu JW, Zhao WM, Wei DZ, Zhong JJ.
Life Sci. 2006 Dec 23;80(3):205-11.

Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion.
Thyagarajan A, Jiang J, Hopf A, Adamec J, Sliva D.
Int J Mol Med. 2006 Oct;18(4):657-64.

Anti-tumor activities of the antlered form of Ganoderma lucidum in allogeneic and syngeneic tumor-bearing mice.
Nonaka Y, Shibata H, Nakai M, Kurihara H, Ishibashi H, Kiso Y, Tanaka T, Yamaguchi H, Abe S.
Biosci Biotechnol Biochem. 2006 Sep;70(9):2028-34.

Ganoderma lucidum inhibits proliferation of human breast cancer cells by down-regulation of estrogen receptor and NF-kappaB signaling.
Jiang J, Slivova V, Sliva D.
Int J Oncol. 2006 Sep;29(3):695-703.

Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1.
Lin KI, Kao YY, Kuo HK, Yang WB, Chou A, Lin HH, Yu AL, Wong CH.
J Biol Chem. 2006 Aug 25;281(34):24111-23.

Polysaccharide purified from Ganoderma lucidum induces gene expression changes in human dendritic cells and promotes T helper 1 immune response in BALB/c mice.
Lin YL, Lee SS, Hou SM, Chiang BL.
Mol Pharmacol. 2006 Aug;70(2):637-44.

[Ganoderma polysaccharides antagonize prostaglandin E2-induced suppression of murine splenocyte IFN-gamma and TNF-alpha mRNA expression]
Zhang Q, Lei LS, Zhu ZG, Yu CL, Wu SG.
Nan Fang Yi Ke Da Xue Xue Bao. 2006 Jun;26(6):780-3.

Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells.
Chang UM, Li CH, Lin LI, Huang CP, Kan LS, Lin SB.
Life Sci. 2006 Aug 15;79(12):1129-39.

Ganoderma lucidum extract inhibits proliferation of SW 480 human colorectal cancer cells.
Xie JT, Wang CZ, Wicks S, Yin JJ, Kong J, Li J, Li YC, Yuan CS.
Exp Oncol. 2006 Mar;28(1):25-9.

Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells by the Ganoderma lucidum and Duchesnea chrysantha extracts.
Kim KC, Kim JS, Son JK, Kim IG.
Cancer Lett. 2007 Feb 8;246(1-2):210-7.

Anti-hepatitis activities in the broth of Ganoderma lucidum supplemented with a Chinese herbal medicine.
Li Y, Yang Y, Fang L, Zhang Z, Jin J, Zhang K.
Am J Chin Med. 2006;34(2):341-9.

In vitro and in vivo protective effects of proteoglycan isolated from mycelia of Ganoderma lucidum on carbon tetrachloride-induced liver injury.
Yang XJ, Liu J, Ye LB, Yang F, Ye L, Gao JR, Wu ZH.
World J Gastroenterol. 2006 Mar 7;12(9):1379-85.

Ganoderma lucidum in cancer research.
Sliva D.
Leuk Res. 2006 Jul;30(7):767-8.

Pharmacological and anti-tumor activities of ganoderma spores processed by top-down approaches.
Liu X, Wang JH, Yuan JP.
J Nanosci Nanotechnol. 2005 Dec;5(12):2001-13.

Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer.
Chen X, Hu ZP, Yang XX, Huang M, Gao Y, Tang W, Chan SY, Dai X, Ye J, Ho PC, Duan W, Yang HY, Zhu YZ, Zhou SF.
Int Immunopharmacol. 2006 Mar;6(3):499-508.

Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells.
Müller CI, Kumagai T, O'Kelly J, Seeram NP, Heber D, Koeffler HP.
Leuk Res. 2006 Jul;30(7):841-8..

Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line.
Liao CH, Hsiao YM, Hsu CP, Lin MY, Wang JC, Huang YL, Ko JL.
Mol Carcinog. 2006 Apr;45(4):220-9.

Ganoderma lucidum mycelia enhance innate immunity by activating NF-kappaB.
Kuo MC, Weng CY, Ha CL, Wu MJ.
J Ethnopharmacol. 2006 Jan 16;103(2):217-22.

101.Ganoderma lucidum mycelium and spore extracts as natural adjuvants for immunotherapy.
Chan WK, Lam DT, Law HK, Wong WT, Koo MW, Lau AS, Lau YL, Chan GC.
J Altern Complement Med. 2005 Dec;11(6):1047-57.

[Comparison of the immunomodulatory effects of spore polysaccharides and broken spore polysaccharides isolated from Ganoderma lucidum on murine splenic lymphocytes and peritoneal macrophages in vitro]
Wang PY, Wang SZ, Lin SQ, Lin ZB.
Beijing Da Xue Xue Bao. 2005 Dec 18;37(6):569-74.

Medicinal mushroom cuts off prostate cancer cells' blood supply.
Johnston N.
Drug Discov Today. 2005 Dec;10(23-24):1584.

Secondary metabolites from Ganoderma lucidum and Spongiporus leucomallellus.
Campos Ziegenbein F, Hanssen HP, König WA.
Phytochemistry. 2006 Jan;67(2):202-11.

Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell.
Cao QZ, Lin ZB.
Life Sci. 2006 Feb 23;78(13):1457-63.

Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum.
Lin ZB.
J Pharmacol Sci. 2005 Oct;99(2):144-53.

[Luminous quack doctor]
[No authors listed]
Praxis (Bern 1994). 2005 Sep 21;94(38):1497.

[Application of flow cytometry on functional assessment of health food]
Yang XF, Huang Q, Huang JM, Li Z, Cai M, Huang JK, Chen BF.
Zhonghua Yu Fang Yi Xue Za Zhi. 2005 Sep;39(5):335-41.

Effects of water-soluble Ganoderma lucidum polysaccharides on the immune functions of patients with advanced lung cancer.
Gao Y, Tang W, Dai X, Gao H, Chen G, Ye J, Chan E, Koh HL, Li X, Zhou S.
J Med Food. 2005 Summer;8(2):159-68.

Effects of Ganoderma lucidum polysaccharides on proliferation and cytotoxicity of cytokine-induced killer cells.
Zhu XL, Lin ZB.
Acta Pharmacol Sin. 2005 Sep;26(9):1130-7.

Ganoderic acid produced from submerged culture of Ganoderma lucidum induces cell cycle arrest and cytotoxicity in human hepatoma cell line BEL7402.
Yang HL.
Biotechnol Lett. 2005 Jun;27(12):835-8.

[Chemistry of polysaccharide Lzps-1 from Ganoderma lucidum spore and anti-tumor activity of its total polysaccharides]
Jiang Y, Wang H, Lü L, Tian GY.
Yao Xue Xue Bao. 2005 Apr;40(4):347-50. Chinese.

A quantum chemical and statistical study of ganoderic acids with cytotoxicity against tumor cell.
Yang HL, Chen GH, Li YQ.
Eur J Med Chem. 2005 Oct;40(10):972-6. Epub 2005 Jul 11.

Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum, in mice.
Gao Y, Gao H, Chan E, Tang W, Xu A, Yang H, Huang M, Lan J, Li X, Duan W, Xu C, Zhou S.
Immunol Invest. 2005;34(2):171-98.

Formulation and in vitro/in vivo evaluation of combining DNA repair and immune enhancing nutritional supplements.
Pero RW, Amiri A, Sheng Y, Welther M, Rich M.
Phytomedicine. 2005 Apr;12(4):255-63.

Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and p38 mitogen-activated protein kinase pathways.
Lin YL, Liang YC, Lee SS, Chiang BL.
J Leukoc Biol. 2005 Aug;78(2):533-43.

Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells.
Li CH, Chen PY, Chang UM, Kan LS, Fang WH, Tsai KS, Lin SB.
Life Sci. 2005 Jun 3;77(3):252-65.

New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants.
Kimura Y.
In Vivo. 2005 Jan-Feb;19(1):37-60.

Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-beta1 from prostate cancer cells.
Stanley G, Harvey K, Slivova V, Jiang J, Sliva D.
Biochem Biophys Res Commun. 2005 Apr 29;330(1):46-52.

Selective induction of apoptosis in murine skin carcinoma cells (CH72) by an ethanol extract of Lentinula edodes.
Gu YH, Belury MA.
Cancer Lett. 2005 Mar 18;220(1):21-8.

Ganoderma total sterol (GS) and GS1 protect rat cerebral cortical neurons
from hypoxia/reoxygenation injury.
Zhao HB, Wang SZ, He QH, Yuan L, Chen AF, Lin ZB.
Life Sci. 2005 Jan 14;76(9):1027-37.

[Progress in research on Ganoderma lucidium spore]
Zhang W, Zeng YS.
Zhong Xi Yi Jie He Xue Bao. 2004 Nov;2(6):463-5.

Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms.
Lin ZB, Zhang HN.
Acta Pharmacol Sin. 2004 Nov;25(11):1387-95.

Ganoderma lucidum extracts inhibit growth and induce actin polymerization in bladder cancer cells in vitro.
Lu QY, Jin YS, Zhang Q, Zhang Z, Heber D, Go VL, Li FP, Rao JY.
Cancer Lett. 2004 Dec 8;216(1):9-20.

Ganoderma lucidum suppresses growth of breast cancer cells through the inhibition of Akt/NF-kappaB signaling.
Jiang J, Slivova V, Harvey K, Valachovicova T, Sliva D.
Nutr Cancer. 2004;49(2):209-16.

Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood.
Chien CM, Cheng JL, Chang WT, Tien MH, Tsao CM, Chang YH, Chang HY, Hsieh JF, Wong CH, Chen ST.
Bioorg Med Chem. 2004 Nov 1;12(21):5603-9.

Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides.
Chen HS, Tsai YF, Lin S, Lin CC, Khoo KH, Lin CH, Wong CH.
Bioorg Med Chem. 2004 Nov 1;12(21):5595-601.

Immune receptors for polysaccharides from Ganoderma lucidum.
Shao BM, Dai H, Xu W, Lin ZB, Gao XM.
Biochem Biophys Res Commun. 2004 Oct 8;323(1):133-41.

Ganoderma lucidum spore extract inhibits endothelial and breast cancer cells in vitro.
Lu QY, Sartippour MR, Brooks MN, Zhang Q, Hardy M, Go VL, Li FP, Heber D.
Oncol Rep. 2004 Sep;12(3):659-62.

Medicinal mushroom extracts inhibit ras-induced cell transformation and the inhibitory effect requires the presence of normal cells.
Hsiao WL, Li YQ, Lee TL, Li N, You MM, Chang ST.
Carcinogenesis. 2004 Jul;25(7):1177-83.

[Activation of mouse macrophages by the alkali-extracted polysaccharide from spore of Ganoderma lucidum]
Tang QJ, Zhang JS, Pan YJ, Reutter W, Fan H.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2004 Mar;20(2):142-4.

Immunomodulatory and antimicrobial effects of some traditional chinese medicinal herbs: a review.
Tan BK, Vanitha J.
Curr Med Chem. 2004 Jun;11(11):1423-30.

Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide.
Cao QZ, Lin ZB.
Acta Pharmacol Sin. 2004 Jun;25(6):833-8.

Cytotoxic activity of methanol extracts from Basidiomycete mushrooms on murine cancer cell lines.
Tomasi S, Lohézic-Le Dévéhat F, Sauleau P, Bézivin C, Boustie J.
Pharmazie. 2004 Apr;59(4):290-3.

Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3.
Jiang J, Slivova V, Valachovicova T, Harvey K, Sliva D.
Int J Oncol. 2004 May;24(5):1093-9.

Biologically active compounds from Aphyllophorales (polypore) fungi.
Zjawiony JK.
J Nat Prod. 2004 Feb;67(2):300-10.

Effects of a genistein-rich extract on PSA levels in men with a history of prostate cancer.
deVere White RW, Hackman RM, Soares SE, Beckett LA, Li Y, Sun B.
Urology. 2004 Feb;63(2):259-63.

A mushroom (Ganoderma capense) lectin with spectacular thermostability, potent mitogenic activity on splenocytes, and antiproliferative activity toward tumor cells.
Ngai PH, Ng TB.
Biochem Biophys Res Commun. 2004 Feb 20;314(4):988-93.

Ganoderma lucidum (Reishi) in cancer treatment.
Sliva D.
Integr Cancer Ther. 2003 Dec;2(4):358-64.

Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum.
Song YS, Kim SH, Sa JH, Jin C, Lim CJ, Park EH.
J Ethnopharmacol. 2004 Jan;90(1):17-20.

Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation.
Iwatsuki K, Akihisa T, Tokuda H, Ukiya M, Oshikubo M, Kimura Y, Asano T, Nomura A, Nishino H.
J Nat Prod. 2003 Dec;66(12):1582-5.

Biologic activity of spores and dried powder from Ganoderma lucidum for the inhibition of highly invasive human breast and prostate cancer cells.
Sliva D, Sedlak M, Slivova V, Valachovicova T, Lloyd FP Jr, Ho NW.
J Altern Complement Med. 2003 Aug;9(4):491-7.

Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients.
Gao Y, Zhou S, Jiang W, Huang M, Dai X.
Immunol Invest. 2003 Aug;32(3):201-15.

Natural products of the medicinal fungus Ganoderma lucidum: occurrence, biological activities, and pharmacological functions.
Shiao MS.
Chem Rec. 2003;3(3):172-80.

Submerged cultivation of Ganoderma lucidum biomass and immunostimulatory effects of fungal polysaccharides.
Berovic M, Habijanic J, Zore I, Wraber B, Hodzar D, Boh B, Pohleven F.
J Biotechnol. 2003 Jun 12;103(1):77-86.

Signaling mechanisms of enhanced neutrophil phagocytosis and chemotaxis by the polysaccharide purified from Ganoderma lucidum.
Hsu MJ, Lee SS, Lee ST, Lin WW.
Br J Pharmacol. 2003 May;139(2):289-98.

Synthesis of beta-(1-->6)-branched beta-(1-->3) glucohexaose and its analogues containing an alpha-(1-->3) linked bond with antitumor activity.
Ning J, Zhang W, Yi Y, Yang G, Wu Z, Yi J, Kong F.
Bioorg Med Chem. 2003 May 15;11(10):2193-203.

Regulatory effect of Ganoderma lucidum polysaccharides on cytotoxic T-lymphocytes induced by dendritic cells in vitro.
Cao LZ, Lin ZB.
Acta Pharmacol Sin. 2003 Apr;24(4):321-6.

Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest.
Lin SB, Li CH, Lee SS, Kan LS.
Life Sci. 2003 Apr 11;72(21):2381-90.

Isoflavone aglycon produced by culture of soybean extracts with basidiomycetes and its anti-angiogenic activity.
Miura T, Yuan L, Sun B, Fujii H, Yoshida M, Wakame K, Kosuna K.
Biosci Biotechnol Biochem. 2002 Dec;66(12):2626-31.

A water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia suppresses azoxymethane-induction of colon cancers in male F344 rats.
Lu H, Kyo E, Uesaka T, Katoh O, Watanabe H.
Oncol Rep. 2003 Mar-Apr;10(2):375-9.

[Isolation, purification and bioactivities of exopoly saccharides from fermented broth of Ganoderma lucidum]
Li P, Zhang K.
Wei Sheng Wu Xue Bao. 2000 Apr;40(2):217-20.

Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance.
Kimura Y, Taniguchi M, Baba K.
Anticancer Res. 2002 Nov-Dec;22(6A):3309-18.

Mechanism of the antiulcerogenic effect of Ganoderma lucidum polysaccharides on indomethacin-induced lesions in the rat.
Gao Y, Zhou S, Wen J, Huang M, Xu A.
Life Sci. 2002 Dec 27;72(6):731-45.

Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cells.
Sliva D, Labarrere C, Slivova V, Sedlak M, Lloyd FP Jr, Ho NW.
Biochem Biophys Res Commun. 2002 Nov 8;298(4):603-12.

Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell.
Hu H, Ahn NS, Yang X, Lee YS, Kang KS.
Int J Cancer. 2002 Nov 20;102(3):250-3.

Regulation on maturation and function of dendritic cells by Ganoderma lucidum polysaccharides.
Cao LZ, Lin ZB.
Immunol Lett. 2002 Oct 1;83(3):163-9.

Regression of prostate cancer following administration of Genistein Combined Polysaccharide (GCP), a nutritional supplement: a case report.
Ghafar MA, Golliday E, Bingham J, Mansukhani MM, Anastasiadis AG, Katz AE.
J Altern Complement Med. 2002 Aug;8(4):493-7.

Polysaccharide purified from Ganoderma lucidum inhibits spontaneous and Fas-mediated apoptosis in human neutrophils through activation of the phosphatidylinositol 3 kinase/Akt signaling pathway.
Hsu MJ, Lee SS, Lin WW.
J Leukoc Biol. 2002 Jul;72(1):207-16.

Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum.
Liu X, Yuan JP, Chung CK, Chen XJ.
Cancer Lett. 2002 Aug 28;182(2):155-61.

Hepatoprotective role of Ganoderma lucidum polysaccharide against BCG-induced immune liver injury in mice.
Zhang GL, Wang YH, Ni W, Teng HL, Lin ZB.
World J Gastroenterol. 2002 Aug;8(4):728-33

New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells.
Gao JJ, Min BS, Ahn EM, Nakamura N, Lee HK, Hattori M.
Chem Pharm Bull (Tokyo). 2002 Jun;50(6):837-40.

New lanostanoids from the fungus Ganoderma concinna.
González AG, León F, Rivera A, Padrón JI, González-Plata J, Zuluaga JC, Quintana J, Estévez F, Bermejo J.
J Nat Prod. 2002 Mar;65(3):417-21.

Mechanism of action of herbal supplement PC-SPES: elucidation of effects of individual herbs of PC-SPES on proliferation and prostate specific gene expression in androgen-dependent LNCaP cells.
Hsieh TC, Wu JM.
Int J Oncol. 2002 Mar;20(3):583-8.

Mushroom-derived preparations in the prevention of H2O2-induced oxidative damage to cellular DNA.
Shi YL, James AE, Benzie IF, Buswell JA.
Teratog Carcinog Mutagen. 2002;22(2):103-11.

Prevention of development of N,N'-dimethylhydrazine-induced colon tumors by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male ICR mice.
Lu H, Kyo E, Uesaka T, Katoh O, Watanabe H.
Int J Mol Med. 2002 Feb;9(2):113-7.

Structural features of immunologically active polysaccharides from Ganoderma lucidum.
Bao XF, Wang XS, Dong Q, Fang JN, Li XY.
Phytochemistry. 2002 Jan;59(2):175-81.

[Study on antitumor activity and mechanism of Ganoderma polysaccharides B]
Zhang Q, Lin Z.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 Sep;19(9):544-7.

Prevention of the development of preneoplastic lesions, aberrant crypt foci, by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male F344 rats.
Lu H, Uesaka T, Katoh O, Kyo E, Watanabe H.
Oncol Rep. 2001 Nov-Dec;8(6):1341-5.

Effects of polysaccharides (FI0-c) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (II).
Gao XX, Wang BX, Fei XF, Zhang J, Gong YJ, Minami M, Nagata T, Ikejima T.
Acta Pharmacol Sin. 2000 Dec;21(12):1186-92.

Effects of polysaccharides (FI0-b) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (I).
Gao XX, Fei XF, Wang BX, Zhang J, Gong YJ, Minami M, Nagata T, Ikejima T.
Acta Pharmacol Sin. 2000 Dec;21(12):1179-85.

Cytotoxicity of Ganoderma lucidum triterpenes.
Wu TS, Shi LS, Kuo SC.
J Nat Prod. 2001 Aug;64(8):1121-2.

Solution properties of antitumor sulfated derivative of alpha-(1-->3)-D-glucan from Ganoderma lucidum.
Zhang L, Zhang M, Zhou Q, Chen J, Zeng F.
Biosci Biotechnol Biochem. 2000 Oct;64(10):2172-8.

Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells.
Cheung WM, Hui WS, Chu PW, Chiu SW, Ip NY.
FEBS Lett. 2000 Dec 15;486(3):291-6.

New lanostanoids from Ganoderma lucidum that induce NAD(P)H:quinone oxidoreductase in cultured hepalcic7 murine hepatoma cells.
Ha TB, Gerhäuser C, Zhang WD, Ho-Chong-Line N, Fourasté I.
Planta Med. 2000 Oct;66(7):681-4.

Role of herbal compounds (PC-SPES) in hormone-refractory prostate cancer: two case reports.
de la Taille A, Hayek OR, Burchardt M, Burchardt T, Katz AE.
J Altern Complement Med. 2000 Oct;6(5):449-51.

Effects of extracts from sporoderm-broken spores of Ganoderma lucidum on HeLa cells.
Zhu HS, Yang XL, Wang LB, Zhao DX, Chen L.
Cell Biol Toxicol. 2000;16(3):201-6.

Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells.
Min BS, Gao JJ, Nakamura N, Hattori M.
Chem Pharm Bull (Tokyo). 2000 Jul;48(7):1026-33.

Ganoderma lucidum extract protects DNA from strand breakage caused by hydroxyl radical and UV irradiation.
Kim KC, Kim IG.
Int J Mol Med. 1999 Sep;4(3):273-7.

New lanostanoids of Ganoderma tsugae.
Su HJ, Fann YF, Chung MI, Won SJ, Lin CN.
J Nat Prod. 2000 Apr;63(4):514-6.

Update from Asia. Asian studies on cancer chemoprevention.
Yun TK.
Ann N Y Acad Sci. 1999;889:157-92. Review.

Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective.
Wasser SP, Weis AL.
Crit Rev Immunol. 1999;19(1):65-96

In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor).
Kim HS, Kacew S, Lee BM.
Carcinogenesis. 1999 Aug;20(8):1637-40.

Mediation of the cytotoxicity of lanostanoids and steroids of Ganoderma tsugae through apoptosis and cell cycle.
Gan KH, Fann YF, Hsu SH, Kuo KW, Lin CN.
J Nat Prod. 1998 Apr;61(4):485-7.

Fip-vvo, a new fungal immunomodulatory protein isolated from Volvariella volvacea.
Hsu HC, Hsu CI, Lin RH, Kao CL, Lin JY.
Biochem J. 1997 Apr 15;323 ( Pt 2):557-65.

The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes.
Wang SY, Hsu ML, Hsu HC, Tzeng CH, Lee SS, Shiao MS, Ho CK.
Int J Cancer. 1997 Mar 17;70(6):699-705.

[Psychoneuroimmunological effects of morphine and the immunoprotection of Ganoderma polysaccharides peptide in morphine-dependent mice]
Lu ZW.
Sheng Li Ke Xue Jin Zhan. 1995 Jan;26(1):45-9.

Trial of a new medium-term model using benzo(a)pyrene induced lung tumor in newborn mice.
Yun TK, Kim SH, Lee YS.
Anticancer Res. 1995 May-Jun;15(3):839-45.

Antitumor active protein-containing glycans from the Chinese mushroom songshan lingzhi, Ganoderma tsugae mycelium.
Zhang J, Wang G, Li H, Zhuang C, Mizuno T, Ito H, Mayuzumi H, Okamoto H, Li J.
Biosci Biotechnol Biochem. 1994 Jul;58(7):1202-5.

[Testing of plant extracts preparations for prevention and non-toxic therapy of oncologic diseases in experimental models]
Bocharova OA, Serebriakova RV.
Vestn Ross Akad Med Nauk. 1994;(2):52-5.

[Effects of Ganoderma polysaccharides on the activity of DNA polymerase alpha of splenocytes and immune function in aged mice]
Lei LS, Lin ZB.
Yao Xue Xue Bao. 1993;28(8):577-82.

The lack of antiplatelet effect of crude extracts from ganoderma lucidum on HIV-positive hemophiliacs.
Gau JP, Lin CK, Lee SS, Wang SR.
Am J Chin Med. 1990;18(3-4):175-9.

Ling Zhi-8: a novel T cell mitogen induces cytokine production and upregulation of ICAM-1 expression.
Haak-Frendscho M, Kino K, Sone T, Jardieu P.
Cell Immunol. 1993 Aug;150(1):101-13.

Antitumor active polysaccharides from the Chinese mushroom Songshan lingzhi, the fruiting body of Ganoderma tsugae.
Wang G, Zhang J, Mizuno T, Zhuang C, Ito H, Mayuzumi H, Okamoto H, Li J.
Biosci Biotechnol Biochem. 1993 Jun;57(6):894-900.

The effect of Ganoderma lucidum on induction of differentiation in leukemic U937 cells.
Lieu CW, Lee SS, Wang SY.
Anticancer Res. 1992 Jul-Aug;12(4):1211-5.

[Chemical studies on immunologically active polysaccharides of Ganoderma lucidum(Leyss. ex Fr.) Karst]
He Y, Li R, Chen Q, Lin Z, Xia D, Ma L.
Zhongguo Zhong Yao Za Zhi. 1992 Apr;17(4):226-8, 256.

Novel cytotoxic principles of Formosan Ganoderma lucidum.
Lin CN, Tome WP, Won SJ.
J Nat Prod. 1991 Jul-Aug;54(4):998-1002.

[In vitro cytotoxicity of Ganoderma lucidum on oral cancer cells]
Chen TW, Wong YK, Lee SS.
Zhonghua Yi Xue Za Zhi (Taipei). 1991 Jul;48(1):54-8.

Evidence for cross-reactive allergens among basidiomycetes: immunoprint-inhibition studies.
De Zubiria A, Horner WE, Lehrer SB.
J Allergy Clin Immunol. 1990 Jul;86(1):26-33.

Antitumor activity of Sarcodon aspratus (Berk.) S. Ito and Ganoderma lucidum (Fr.) Karst.
Maruyama H, Yamazaki K, Murofushi S, Konda C, Ikekawa T.
J Pharmacobiodyn. 1989 Feb;12(2):118-23.

[Effect of six edible plants on the development of AFB1-induced gamma-glutamyltranspeptidase-positive hepatocyte foci in rats]
Chen ZY, Yan RQ, Qin GZ, Qin LL.
Zhonghua Zhong Liu Za Zhi. 1987 Mar;9(2):109-11.

Human sensitization to Ganoderma antigen.
Tarlo SM, Bell B, Srinivasan J, Dolovich J, Hargreave FE.
J Allergy Clin Immunol. 1979 Jul;64(1):43-9.

Effect of polysaccharides from Ganoderma applanatum on immune responses. I. Enhancing effect on the induction of delayed hypersensitivity in mice.
Nakashima S, Umeda Y, Kanada T.
Microbiol Immunol. 1979;23(6):501-13.

Antitumor polysaccharides from some polyporaceae, Ganoderma applanatum (Pers.) Pat and Phellinus linteus (Berk. et Curt) Aoshima.
Sasaki T, Arai Y, Ikekawa T, Chihara G, Fukuoka F.
Chem Pharm Bull (Tokyo). 1971 Apr;19(4):821-6.

Ganoderma lucidum polysaccharides antagonize the suppression on lymphocytes induced by culture supernatants of B16F10 melanoma cells.
Sun LX, Lin ZB, Duan XS, Lu J, Ge ZH, Li XJ, Li M, Xing EH, Jia J, Lan TF, Li WD. J Pharm Pharmacol. 2011 May;63(5):725-735. doi: 10.1111/j.2042-7158.2011.01266.x.

GMI, an immunomodulatory protein from Ganoderma microsporum, induces autophagy in non-small cell lung cancer cells.
Hsin IL, Ou CC, Wu TC, Jan MS, Wu MF, Chiu LY, Lue KH, Ko JL.
Autophagy. 2011 Aug 1;7(8).

Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNFα induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK.
Watanabe K, Shuto T, Sato M, Onuki K, Mizunoe S, Suzuki S, Sato T, Koga T, Suico MA, Kai H, Ikeda T.
Biochem Biophys Res Commun. 2011 Mar 29.

Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaidTM: Mechanism of activity.
Jiang J, Eliaz I, Sliva D.
Int J Oncol. 2011 Apr 4. doi: 10.3892/ijo.2011.996.
Ganoderma lucidum exerts anti-tumor effects on ovarian cancer cells and enhances their sensitivity to cisplatin.

Zhao S, Ye G, Fu G, Cheng JX, Yang BB, Peng C.
Int J Oncol. 2011 May;38(5):1319-27. doi: 10.3892/ijo.2011.965. Epub 2011 Mar 8.

Enhancement of Cyclophosphamide-Induced Antitumor Effect by a Novel Polysaccharide from Ganoderma atrum in Sarcoma 180-Bearing Mice.
Li W, Nie S, Chen Y, Wang Y, Li C, Xie M.
J Agric Food Chem. 2011 Mar 22.

Cellular and molecular mechanisms of the Ganoderma applanatum extracts induces apoptosis on SGC-7901 gastric cancer cells.
Ma J, Liu C, Chen Y, Jiang J, Qin Z.
Cell Biochem Funct. 2011 Apr;29(3):175-82. doi: 10.1002/cbf.1735. Epub 2011 Feb 24.

Ergosta-7,22-diene-2β,3α,9α-triol from the Fruit Bodies of Ganoderma lucidum Induces Apoptosis in Human Myelocytic HL-60 Cells.
Lee MK, Hung TM, Cuong TD, Na M, Kim JC, Kim EJ, Park HS, Choi JS, Lee I, Bae K, Hattori M, Min BS.
Phytother Res. 2011 Mar 11. doi: 10.1002/ptr.3447.

Ganoderma atrum polysaccharide induces anti-tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response.
Li WJ, Chen Y, Nie SP, Xie MY, He M, Zhang SS, Zhu KX.
J Cell Biochem. 2011 Mar;112(3):860-71. doi: 10.1002/jcb.22993.

Determination of Trace Elements in Anti-influenza Virus Mushrooms.
Wang L, Hou Y.
Biol Trace Elem Res. 2011 Feb 8.