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| Ganoderma lucidum Polysaccharides Ameliorate Acetaminophen-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Apoptosis along the Nrf2 Pathway. |
| Zhang N, Han Z, Zhang R, Liu L, Gao Y, Li J, Yan M. |
| Nutrients. 2024 Jun 13;16(12):1859. doi: 10.3390/nu16121859. |
| COP-22 Alleviates D-Galactose-Induced Brain Aging by Attenuating Oxidative Stress, Inflammation, and Apoptosis in Mice. |
| Ma Y, Wang X, Li X, Chen X, Teng Z, Wang X, Yang J, Liu G. |
| Mol Neurobiol. 2024 Sep;61(9):6708-6720. doi: 10.1007/s12035-024-03976-1. Epub 2024 Feb 12. |
| Triterpenes from antler-shaped fruiting body of Ganoderma lucidum and their hepatoprotective activities. |
| Shao H, Li Y, Wu C, Chen R, Kang J. |
| Phytochemistry. 2024 Aug;224:114148. doi: 10.1016/j.phytochem.2024.114148. Epub 2024 May 18. |
| Minor ergosteroids and a 19-nor labdane-type diterpenoid with anti-inflammatory effects from Ganoderma lucidum. |
| Cai D, Liu YY, Tang XP, Zhang M, Cheng YX. |
| Phytochemistry. 2024 Jun;222:114052. doi: 10.1016/j.phytochem.2024.114052. Epub 2024 Mar 20. |
| Ganomycin C, a Ganoderma Meroterpenoid, Alleviates Pain and Absence Seizures in Mice by Targeting Ca(v)3.1 and Ca(v)3.2 Low-Voltage-Gated Calcium Channels. |
| Dong D, Quan S, Wu M, Du S, Yan H, Gong Y, Qiu M, Peng X, Nian Y. |
| Phytother Res. 2025 Mar 27. doi: 10.1002/ptr.8486. Online ahead of print. |
| Removal of pharmaceutical compounds and toxicology study in wastewater using Malaysian fungal Ganoderma lucidum. |
| Mohd Hanafiah Z, Wan Mohtar WHM, Wan-Mohtar WAAQI, Bithi AS, Rohani R, Indarto A, Yaseen ZM, Sharil S, Binti Abdul Manan TS. |
| Chemosphere. 2024 Jun;358:142209. doi: 10.1016/j.chemosphere.2024.142209. Epub 2024 Apr 30. |
| Synthesis and Biological Activity of Tetracyclic Dispiro Core Derivatives of Natural Products Dispirocochlearoids A-C. |
| Pei J, Wang Y, Shi S, Chen L, Yin J, Nan F. |
| Org Lett. 2024 Nov 15;26(45):9654-9658. doi: 10.1021/acs.orglett.4c03358. Epub 2024 Nov 1. |
| Design, synthesis and biological evaluation of novel curcumin-fluorouracil hybrids as potential anti-cancer agents. |
| Wang X, Li X, Zhang X, Wang X, Yang J, Liu G. |
| Biochem Pharmacol. 2024 Dec;230(Pt 1):116559. doi: 10.1016/j.bcp.2024.116559. Epub 2024 Sep 24. |
| Determination via an Integration Strategy of the Potential Dermal ECM Reconstruction Mechanism by Which the WAW Formula Alleviates Skin Aging. |
| Lin Y, Chang Y, Maeng Y, Liu X, Liu X, Meng H, Yi F. |
| J Cosmet Dermatol. 2025 Apr;24(4):e70124. doi: 10.1111/jocd.70124. |
| Combined NMR and MS-based metabonomics and real-time PCR analyses reveal dynamic metabolic changes of Ganoderma lucidum during fruiting body growing. |
| Liu C, Chen F, Fan X, Liu B, Chai X, He S, Huang T, Wang X, Liu L, Liu H, Zeng D, Jiang B, Zhang X, Liu M. |
| Food Res Int. 2024 Mar;180:114056. doi: 10.1016/j.foodres.2024.114056. Epub 2024 Jan 26. |
| The Importance of Traditional Chinese Medicine in the Intervention and Treatment of HIV while Considering its Safety and Efficacy. |
| Shahrajabian MH, Sun W. |
| Curr HIV Res. 2023;21(6):331-346. doi: 10.2174/011570162X271199231128092621. |
| Modulating Hyperpolarization-Activated Cation Currents through Small Molecule Perturbations: Magnitude and Gating Control. |
| Chen CS, So EC, Wu SN. |
| Biomedicines. 2023 Aug 2;11(8):2177. doi: 10.3390/biomedicines11082177. |
| Modeling and optimization of the protocol of complex chromatography separation of cyclooxygenase-2 inhibitors from Ganoderma lucidum spore. |
| Li S, Hou W, Li Y, Liu Z, Yun H, Liu Q, Niu H, Liu C, Zhang Y. |
| Phytochem Anal. 2023 Jun;34(4):431-442. doi: 10.1002/pca.3224. Epub 2023 Mar 23. |
| Ganoderma lucidum polysaccharide peptide alleviates hyperuricemia by regulating adenosine deaminase and urate transporters. |
| Lin S, Meng J, Li F, Yu H, Lin D, Lin S, Li M, Zhou H, Yang B. |
| Food Funct. 2022 Dec 13;13(24):12619-12631. doi: 10.1039/d2fo02431d. |
| The Potential of Plant-Derived Extracts and Compounds to Augment Anticancer Effects of Chemotherapeutic Drugs. |
| Ng CX, Affendi MM, Chong PP, Lee SH. |
| Nutr Cancer. 2022;74(9):3058-3076. doi: 10.1080/01635581.2022.2069274. Epub 2022 Jun 8. |
| Efficacy of complementary medicine for nonsteroidal anti-inflammatory drug-induced small intestinal injuries: A narrative review. |
| Cho M, Bu Y, Park JW, Rahman H, Ko SJ. |
| Medicine (Baltimore). 2021 Dec 3;100(48):e28005. doi: 10.1097/MD.0000000000028005. |
| Self-nanoemulsifying composition containing curcumin, quercetin, Ganoderma lucidum extract powder and probiotics for effective treatment of type 2 diabetes mellitus in streptozotocin induced rats. |
| Khursheed R, Singh SK, Kumar B, Wadhwa S, Gulati M, A A, Awasthi A, Vishwas S, Kaur J, Corrie L, K R A, Kumar R, Jha NK, Gupta PK, Zacconi F, Dua K, Chitranshi N, Mustafa G, Kumar A. |
| Int J Pharm. 2022 Jan 25;612:121306. doi: 10.1016/j.ijpharm.2021.121306. Epub 2021 Nov 20. |
| FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma. |
| Peng XR, Wang Q, Wang HR, Hu K, Xiong WY, Qiu MH. |
| Bioorg Chem. 2021 Nov;116:105338. doi: 10.1016/j.bioorg.2021.105338. Epub 2021 Sep 8. |
| Development of mushroom polysaccharide and probiotics based solid self-nanoemulsifying drug delivery system loaded with curcumin and quercetin to improve their dissolution rate and permeability: State of the art. |
| Khursheed R, Singh SK, Wadhwa S, Gulati M, Kapoor B, Jain SK, Gowthamarajan K, Zacconi F, Chellappan DK, Gupta G, Jha NK, Gupta PK, Dua K. |
| Int J Biol Macromol. 2021 Oct 31;189:744-757. doi: 10.1016/j.ijbiomac.2021.08.170. Epub 2021 Aug 28. |
| CNS anti-depressant, anxiolytic and analgesic effects of Ganoderma applanatum (mushroom) along with ligand-receptor binding screening provide new insights: Multi-disciplinary approaches. |
| Hossen SMM, Islam MJ, Hossain MR, Barua A, Uddin MG, Emon NU. |
| Biochem Biophys Rep. 2021 Jul 9;27:101062. doi: 10.1016/j.bbrep.2021.101062. eCollection 2021 Sep. |
| Effects of Ganoderma lucidum Polysaccharides on Different Pathways Involved in the Development of Spinal Cord Ischemia Reperfusion Injury: Biochemical, Histopathologic, and Ultrastructural Analysis in a Rat Model. |
| Kahveci R, Kahveci FO, Gokce EC, Gokce A, Kısa Ü, Sargon MF, Fesli R, Gürer B. |
| World Neurosurg. 2021 Jun;150:e287-e297. doi: 10.1016/j.wneu.2021.02.129. Epub 2021 Mar 6. |
| Protective effects of curcumin and Ganoderma lucidum on hippocampal damage caused by the organophosphate insecticide chlorpyrifos in the developing rat brain: Stereological, histopathological and immunohistochemical study. |
| Eronat K, Sağır D. |
| Acta Histochem. 2020 Oct;122(7):151621. doi: 10.1016/j.acthis.2020.151621. Epub 2020 Sep 9.PMID: 33066842 |
| Exploring role of probiotics and Ganoderma lucidum extract powder as solid carriers to solidify liquid self-nanoemulsifying delivery systems loaded with curcumin. |
| Khursheed R, Singh SK, Wadhwa S, Gulati M, Awasthi A, Kumar R, Ramanunny AK, Kapoor B, Kumar P, Corrie L. |
| Carbohydr Polym. 2020 Dec 15;250:116996. doi: 10.1016/j.carbpol.2020.116996. Epub 2020 Aug 29. |
| Gano oil: A novel antinociceptive agent extracted from Ganoderma lucidum inhibits paw oedema and relieves pain by hypnotic and analgesic actions of fatty acid amides. |
| Chen X, Veena RK, Ramya H, Janardhanan KK, George V. |
| J Ethnopharmacol. 2020 Dec 5;263:113144. doi: 10.1016/j.jep.2020.113144. Epub 2020 Jul 27. |
| Novel cobiomass degradation of NSAIDs by two wood rot fungi, Ganoderma applanatum and Laetiporus sulphureus: Ligninolytic enzymes induction, isotherm and kinetic studies. |
| Bankole PO, Adekunle AA, Jeon BH, Govindwar SP. |
| Ecotoxicol Environ Saf. 2020 Oct 15;203:110997. doi: 10.1016/j.ecoenv.2020.110997. Epub 2020 Jul 16. |
| Effects of Extraction Temperature on Efficacy of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Aqueous Extract against Oxidative Stress. |
| Tulsawani R, Sharma P, Manimaran M, Koganti P, Singh M, Meena DK, Negi PS, Misra K. |
| Int J Med Mushrooms. 2020;22(6):547-558. doi: 10.1615/IntJMedMushrooms.2020035074. |
| (+/-)-Lucidumone, a COX-2 Inhibitory Caged Fungal Meroterpenoid from Ganoderma lucidum. |
| Yan YM, Zhang HX, Liu H, Wang Y, Wu JB, Li YP, Cheng YX. |
| Org Lett. 2019 Nov 1;21(21):8523-8527. doi: 10.1021/acs.orglett.9b02840. Epub 2019 Sep 26. |
| Neuropharmacological Effect and Clinical Applications of Ganoderma (Lingzhi). |
| Cui X, Zhang Y. |
| Adv Exp Med Biol. 2019;1182:143-157. doi: 10.1007/978-981-32-9421-9_5. Review. |
| Evaluation of laccase production by Ganoderma lucidum in submerged and solid-state fermentation using different inducers. |
| Rodrigues EM, Karp SG, Malucelli LC, Helm CV, Alvarez TM. |
| J Basic Microbiol. 2019 Aug;59(8):784-791. doi: 10.1002/jobm.201900084. Epub 2019 Jul 1. |
| Anti-inflammatory, anti-nociceptive and sedative-hypnotic activities of lucidone D extracted from Ganoderma lucidum. |
| Feng X, Wang Y. |
| Cell Mol Biol (Noisy-le-grand). 2019 Apr 30;65(4):37-42. |
| Protection against Gut Inflammation and Sepsis in Mice by the Autodigested Product of the Lingzhi Medicinal Mushroom, Ganoderma lingzhi (Agaricomycetes). |
| Ishimoto Y, Ishibashi KI, Yamanaka D, Adachi Y, Ito H, Igami K, Miyazaki T, Ohno N. |
| Int J Med Mushrooms. 2018;20(9):809-823. doi: 10.1615/IntJMedMushrooms.2018027359. |
| Ganoderma lucidum: Persuasive biologically active constituents and their health endorsement. |
| Ahmad MF. |
| Biomed Pharmacother. 2018 Nov;107:507-519. doi: 10.1016/j.biopha.2018.08.036. Epub 2018 Aug 13. Review. |
| Meroterpenoid dimers from Ganoderma cochlear and their cytotoxic and COX-2 inhibitory activities. |
| Qin FY, Yan YM, Tu ZC, Cheng YX. |
| Fitoterapia. 2018 Sep;129:167-172. doi: 10.1016/j.fitote.2018.06.019. Epub 2018 Jun 30. |
| Three-Dimensional Electrohydrodynamic Printing and Spinning of Flexible Composite Structures for Oral Multidrug Forms. |
| Wu S, Li JS, Mai J, Chang MW. |
| ACS Appl Mater Interfaces. 2018 Jul 25;10(29):24876-24885. doi: 10.1021/acsami.8b08880. Epub 2018 Jul 10. |
| Computational Insights into the Molecular Mechanism of the High Immunomodulatory Activity of LZ-8 Protein Isolated from the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes). |
| Bao DP, Bai R, Gao YN, Wu YY, Wang Y. |
| Int J Med Mushrooms. 2018;20(6):537-548. doi: 10.1615/IntJMedMushrooms.2018026264. |
| Two new farnesyl phenolic compounds with anti-inflammatory activities from Ganoderma duripora. |
| Liu JQ, Lian CL, Hu TY, Wang CF, Xu Y, Xiao L, Liu ZQ, Qiu SQ, Cheng BH. |
| Food Chem. 2018 Oct 15;263:155-162. doi: 10.1016/j.foodchem.2018.04.097. Epub 2018 Apr 25. |
| Structural Elucidation and Biomimetic Synthesis of (±)-Cochlactone A with Anti-Inflammatory Activity. |
| Peng XR, Lu SY, Shao LD, Zhou L, Qiu MH. |
| J Org Chem. 2018 May 18;83(10):5516-5522. doi: 10.1021/acs.joc.8b00525. Epub 2018 May 4. |
| Meroterpenoids from the fruiting bodies of Ganoderma theaecolum. |
| Luo Q, Tu ZC, Yang ZL, Cheng YX. |
| Fitoterapia. 2018 Mar;125:273-280. doi: 10.1016/j.fitote.2018.01.015. Epub 2018 Feb 1. |
| Polysaccharides derived from Ganoderma lucidum fungus mycelia ameliorate indomethacin-induced small intestinal injury via induction of GM-CSF from macrophages. |
| Nagai K, Ueno Y, Tanaka S, Hayashi R, Shinagawa K, Chayama K. |
| Cell Immunol. 2017 Oct;320:20-28. doi: 10.1016/j.cellimm.2017.08.001. Epub 2017 Aug 4. |
| Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer's disease: A review. |
| Jiang Y, Gao H, Turdu G. |
| Bioorg Chem. 2017 Dec;75:50-61. doi: 10.1016/j.bioorg.2017.09.004. Epub 2017 Sep 6. Review. |
| Immunomodulatory Activity of Ganoderma atrum Polysaccharide on Purified T Lymphocytes through Ca<sup>2+</sup>/CaN and Mitogen-Activated Protein Kinase Pathway Based on RNA Sequencing. |
| Xiang QD, Yu Q, Wang H, Zhao MM, Liu SY, Nie SP, Xie MY. |
| J Agric Food Chem. 2017 Jul 5;65(26):5306-5315. doi: 10.1021/acs.jafc.7b01763. Epub 2017 Jun 26. |
| Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. |
| Jiao Y, Xie T, Zou LH, Wei Q, Qiu L, Chen LX. |
| Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61. doi: 10.1016/j.bmcl.2016.06.023. Epub 2016 Jun 9. |
| De novo transcriptome analyses of host-fungal interactions in oil palm (Elaeis guineensis Jacq.). |
| Ho CL, Tan YC, Yeoh KA, Ghazali AK, Yee WY, Hoh CC. |
| BMC Genomics. 2016 Jan 19;17:66. doi: 10.1186/s12864-016-2368-0. |
| Optimization of laccase production by two strains of Ganoderma lucidum using phenolic and metallic inducers. |
| Kuhar F, Papinutti L. |
| Rev Argent Microbiol. 2014 Apr-Jun;46(2):144-9. doi: 10.1016/S0325-7541(14)70063-X. |
| An in vitro study of neuroprotective properties of traditional Chinese herbal medicines thought to promote healthy ageing and longevity. |
| Shen B, Truong J, Helliwell R, Govindaraghavan S, Sucher NJ. |
| BMC Complement Altern Med. 2013 Dec 27;13:373. doi: 10.1186/1472-6882-13-373. |
| In vivo screening of four phytochemicals/extracts and a fungal immunomodulatory protein against an Eimeria acervulina infection in broilers. |
| Peek HW, Halkes SB, Mes JJ, Landman WJ. |
| Vet Q. 2013;33(3):132-8. doi: 10.1080/01652176.2013.844378. Epub 2013 Oct 25. |
| [Study on effective constituents extracted from fibrous roots of Salvia miltiorrhiza with degrading multi-enzymes from taishan Ganoderma lucidum]. |
| Li YL, Xin XM, Miao ZM, Shi RJ, Hao GP. |
| Zhongguo Zhong Yao Za Zhi. 2013 Mar;38(5):678-82. Chinese. |