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Aging and Beauty
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Association of alpha-Klotho with anti-aging effects of Ganoderma lucidum in animal models.
Liu X, Zhao J, Liu J, Huang Y, Deng W, Yan L, Cui M, Pan X, Xiao H, Liu X.
J Ethnopharmacol. 2025 Apr 9;345:119597. doi: 10.1016/j.jep.2025.119597. Epub 2025 Mar 7.
 
Macrofungal Extracts as a Source of Bioactive Compounds for Cosmetical Anti-Aging Therapy: A Comprehensive Review.
Paterska M, Czerny B, Cielecka-Piontek J.
Nutrients. 2024 Aug 22;16(16):2810. doi: 10.3390/nu16162810.
 
Mushrooms in modern cosmetics: unlocking anti-aging, antioxidant, and therapeutic potential.
Rukhsar S, Usman M, Yousaf N, Murtaza G, Manzoor MA, Azam M.
Arch Dermatol Res. 2025 Mar 9;317(1):542. doi: 10.1007/s00403-025-04048-7.
 
High-content screening identifies ganoderic acid A as a senotherapeutic to prevent cellular senescence and extend healthspan in preclinical models.
Chen L, Wu B, Mo L, Chen H, Yin X, Zhao Y, Cui Z, Cui F, Chen L, Deng Q, Gao C, Yao P, Li Y, Tang Y.
Nat Commun. 2025 Mar 24;16(1):2878. doi: 10.1038/s41467-025-58188-5.
 
COP-22 Alleviates D-Galactose-Induced Brain Aging by Attenuating Oxidative Stress, Inflammation, and Apoptosis in Mice.
Ma Y, Wang X, Li X, Chen X, Teng Z, Wang X, Yang J, Liu G.
Mol Neurobiol. 2024 Sep;61(9):6708-6720. doi: 10.1007/s12035-024-03976-1. Epub 2024 Feb 12.
 
Ganoderma lucidum dry extract supplementation modulates T lymphocyte function in older women.
Iser-Bem PN, Lobato TB, Alecrim-Zeza AL, Dos Santos de Oliveira LC, Passos MEP, Manuel R, Diniz VLS, Correa IS, de Oliveira SP, Silva EBD, Almeida MM, Dias BB, Gritte RB, Levada-Pires AC, Masi LN, Hatanaka E, Pithon-Curi TC, Hirabara SM, Fabi JP, Curi R, Gorjao R.
Br J Nutr. 2024 Jul 28;132(2):130-140. doi: 10.1017/S0007114524001144. Epub 2024 May 27.
 
Bioactive components, pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil: A review.
Liu J, Zhang B, Wang L, Li S, Long Q, Xiao X.
Chin Herb Med. 2024 Jan 17;16(3):375-391. doi: 10.1016/j.chmed.2023.09.007. eCollection 2024 Jul.
 
Research Progress on the Biological Activity of Ganoderic Acids in Ganoderma lucidum over the Last Five Years.
Wang S, Wang L, Shangguan J, Jiang A, Ren A.
Life (Basel). 2024 Oct 21;14(10):1339. doi: 10.3390/life14101339.
 
GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation.
Cheng Y, Zheng G, Huang H, Ni J, Zhao Y, Sun Y, Chang Y, Liu S, He F, Li D, Guo Y, Miao Y, Xu M, Wang D, Zhang Y, Hua Y, Yang S, Fan G, Ma C.
Theranostics. 2025 Mar 18;15(10):4345-4367. doi: 10.7150/thno.110324. eCollection 2025.
 
Extraction Optimization and Bioactivity of Polysaccharides from Ganoderma leucocontextum Spores.
Peng S, Ou Y, Zhang Y, Yao H, Chen WH.
Pharmaceuticals (Basel). 2025 Feb 11;18(2):241. doi: 10.3390/ph18020241.
 
Mitigating Oxidative Stress and Promoting Cellular Longevity with Mushroom Extracts.
Abdelkader ME, Mediatrice H, Lin D, Lin Z, Aggag SA.
Foods. 2024 Dec 13;13(24):4028. doi: 10.3390/foods13244028.
 
Extraction, purification, structural characterization, biological activity, mechanism of action and application of polysaccharides from Ganoderma lucidum: A review.
Ding L, Shangguan H, Wang X, Liu J, Shi Y, Xu X, Xie Y.
Int J Biol Macromol. 2025 Feb;288:138575. doi: 10.1016/j.ijbiomac.2024.138575. Epub 2024 Dec 9.
 
Evaluation of cosmetic efficacy of lychee seed fermentation liquid.
Yan Y, Fu H, Tang Y, Huang T, Zou X, Su N, Wang D, Wang C, Li M.
Bioresour Bioprocess. 2024 Oct 31;11(1):104. doi: 10.1186/s40643-024-00818-9.
 
Ganoderic acid a alleviates Aβ25-35-induced HT22 cell apoptosis through the ERK/MAPK pathway: a system pharmacology and in vitro experimental validation.
Shao N, Lu Q, Ouyang Z, Yang P, Wei T, Wang J, Cai B.
Metab Brain Dis. 2024 Dec 3;40(1):51. doi: 10.1007/s11011-024-01429-1.
 
ATP deficiency triggers ganoderic acids accumulation via fatty acid beta-oxidation pathway in Ganoderma lucidum.
Liu W, Sun Y, Yue S, Kong Y, Cong Q, Lan Y, Zhao M, Shi L.
Microb Cell Fact. 2025 Mar 11;24(1):62. doi: 10.1186/s12934-025-02668-2.
 
Research progress of Ganoderma lucidum polysaccharide in prevention and treatment of Atherosclerosis.
Ma Y, Han J, Wang K, Han H, Hu Y, Li H, Wu S, Zhang L.
Heliyon. 2024 Jun 19;10(12):e33307. doi: 10.1016/j.heliyon.2024.e33307. eCollection 2024 Jun 30.
 
Evaluation of Favorable Conditions to Improve Biomass Production and Antioxidant Activity by the Egyptian Ganoderma resinaceum EGM and Ganoderma mbrekobenum EGDA (Agaricomycetes).
El-Esseily SR, El-Fallal AA, El-Dein MMN, El-Sayed AKA.
Int J Med Mushrooms. 2025;27(4):53-70. doi: 10.1615/IntJMedMushrooms.2024057141.
 
Ganoderma lucidum Extract Modulates Gene Expression Profiles Associated with Antioxidant Defense, Cytoprotection, and Senescence in Human Dermal Fibroblasts: Investigation of Quantitative Gene Expression by qPCR.
Kühnel H, Seiler M, Feldhofer B, Ebrahimian A, Maurer M.
Curr Issues Mol Biol. 2025 Feb 18;47(2):130. doi: 10.3390/cimb47020130.
 
Ganoderma Lucidum polysaccharide peptide (GL-PP2): A potential therapeutic agent against sepsis-induced organ injury by modulating Nrf2/NF-kappaB pathways.
Yang T, Fang H, Lin D, Yang S, Luo H, Wang L, Yang B.
Int J Biol Macromol. 2025 Jan;285:138378. doi: 10.1016/j.ijbiomac.2024.138378. Epub 2024 Dec 4.
 
Adding-value to Ganoderma lingzhi by producing enzymes and antioxidant compounds under submerged fermentation using different culture media.
Oliveira-Junior SD, Silva GL, Pessoa VA, Vasconcelos AS, Silva DF, Soares LBN, Chevreuil LR, Santos ES, Sales-Campos C.
Braz J Biol. 2024 Oct 7;84:e283882. doi: 10.1590/1519-6984.283882. eCollection 2024.
 
Exploring the bioactivity potential of indigenous Ganoderma species from Northern Serbia: insights into antioxidant and anti-acetylcholinesterase properties.
Rašeta M, Mišković J, Krsmanović N, Čapelja E, Berežni S, Pintać Šarac D, Karaman M.
Nat Prod Res. 2024 Oct 15:1-12. doi: 10.1080/14786419.2024.2415437. Online ahead of print.
 
In vitro evaluation of the antitumor and antioxidant effects of purified and characterized polysaccharides from Ganoderma applanatum.
Ni DR, Li HY, Li ZP, Liu JW.
Ann Med. 2024 Dec;56(1):2411010. doi: 10.1080/07853890.2024.2411010. Epub 2024 Nov 16.
 
Metabolite profiling, antioxidant and anti-glycemic activities of Tartary buckwheat processed by solid-state fermentation(SSF)with Ganoderma lucidum.
Zhang R, Cen Q, Hu W, Chen H, Hui F, Li J, Zeng X, Qin L.
Food Chem X. 2024 Apr 10;22:101376. doi: 10.1016/j.fochx.2024.101376. eCollection 2024 Jun 30.
 
Establishment of a visual assessment platform for total antioxidant capacity of Ganoderma sichuanense based on Arg-CeO(2) hydrogel nanozyme utilizing a self-programmed smartphone app and a self-designed 3D-printed device.
Tan S, Tan M, Zhang T, Gao L, Li Y, Xu X, Yang ZQ.
Mikrochim Acta. 2024 Nov 29;191(12):770. doi: 10.1007/s00604-024-06840-0.
 
Optimization of Submerged Fermentation Conditions for Polysaccharide Production in Species of the Genus Ganoderma (Agaricomycetes) and Comparative Analysis of the Antioxidant Activities of Different Strains.
Luo S, Luo Y, Yuan Y, Zhou J, Huang W, Wu X, Cao TX, Du P.
Int J Med Mushrooms. 2025;27(1):13-27. doi: 10.1615/IntJMedMushrooms.2024056392.
 
Mushrooms in modern cosmetics: unlocking anti-aging, antioxidant, and therapeutic potential.
Rukhsar S, Usman M, Yousaf N, Murtaza G, Manzoor MA, Azam M.
Arch Dermatol Res. 2025 Mar 9;317(1):542. doi: 10.1007/s00403-025-04048-7.
 
Molecular networking and Paterno-Buchi reaction guided glycerides characterization and antioxidant activity assessment of Ganoderma lucidum spore oil.
Ren QX, Wang R, Mu QR, Chen L, Chen M, Wang LJ, Li P, Yang H, Gao W.
Food Chem. 2025 Mar 15;468:142500. doi: 10.1016/j.foodchem.2024.142500. Epub 2024 Dec 15.
 
A Review of Ganoderma lucidum Polysaccharide: Preparations, Structures, Physicochemical Properties and Application.
Zhong Y, Tan P, Lin H, Zhang D, Chen X, Pang J, Mu R.
Foods. 2024 Aug 24;13(17):2665. doi: 10.3390/foods13172665.
 
Optimization of ultrasonic-assisted debittering of Ganoderma lucidum using response surface methodology, characterization, and evaluation of antioxidant activity.
Chen S, Song S, Tan Y, He S, Ren X, Li Z, Liu Y.
PeerJ. 2024 Oct 14;12:e17943. doi: 10.7717/peerj.17943. eCollection 2024.
 
Ganoderma lucidum Polysaccharides Ameliorate Acetaminophen-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Apoptosis along the Nrf2 Pathway.
Zhang N, Han Z, Zhang R, Liu L, Gao Y, Li J, Yan M.
Nutrients. 2024 Jun 13;16(12):1859. doi: 10.3390/nu16121859.
 
The effects of Ganoderma leucocontextum triterpenoids treatment on the D-galactose and aluminum chloride-induced Alzheimer-like pathology in mouse brain.
Qi Z, Deng S, Wu Y, Ye B.
J Ethnopharmacol. 2024 Nov 15;334:118530. doi: 10.1016/j.jep.2024.118530. Epub 2024 Jul 6.
 
Ganoderma lucidum triterpenoids investigating their role in medicinal applications and genomic protection.
Raza SHA, Zhong R, Li X, Pant SD, Shen X, BinMowyna MN, Luo L, Lei H.
J Pharm Pharmacol. 2024 Dec 2;76(12):1535-1551. doi: 10.1093/jpp/rgae133.
 
The Protective Effects of Ganoderma lucidum Active Peptide GLP4 on Lung Injury Induced by Cadmium Poisoning in Mice.
Zhu S, Wang X, Liu G.
Toxics. 2024 May 22;12(6):378. doi: 10.3390/toxics12060378.
 
The Biological Activity of Ganoderma lucidum on Neurodegenerative Diseases: The Interplay between Different Active Compounds and the Pathological Hallmarks.
Lian W, Yang X, Duan Q, Li J, Zhao Y, Yu C, He T, Sun T, Zhao Y, Wang W.
Molecules. 2024 May 26;29(11):2516. doi: 10.3390/molecules29112516.
 
Dynamic changes of nutrients, isoflavone composition and antioxidant activities during liquid-state fermentation of soybean embryo homogenate by Ganoderma lucidum.
Kim GY, Kwon YS, Gebru YA, Kim YH, Kang DH, Kim MK, Choi HS.
Food Chem X. 2025 Feb 14;26:102283. doi: 10.1016/j.fochx.2025.102283. eCollection 2025 Feb.
 
Publisher Correction: Establishment of a visual assessment platform for total antioxidant capacity of Ganoderma sichuanense based on Arg-CeO2 hydrogel nanozyme utilizing a self-programmed smartphone app and a self-designed 3D-printed device.
Tan S, Tan M, Zhang T, Gao L, Li Y, Xu X, Yang ZQ.
Mikrochim Acta. 2024 Dec 21;192(1):18. doi: 10.1007/s00604-024-06888-y.
 
A review of polysaccharides from Ganoderma lucidum: Preparation methods, structural characteristics, bioactivities, structure-activity relationships and potential applications.
Yang M, Qin X, Liu X.
Int J Biol Macromol. 2025 Apr;303:140645. doi: 10.1016/j.ijbiomac.2025.140645. Epub 2025 Feb 3.
 
Ganoderma lucidum polysaccharide promotes broiler health by regulating lipid metabolism, antioxidants, and intestinal microflora.
Gao YY, Zhou YH, Liu XP, Di B, He JY, Wang YT, Guo PT, Zhang J, Wang CK, Jin L.
Int J Biol Macromol. 2024 Sep 23;280(Pt 3):135918. doi: 10.1016/j.ijbiomac.2024.135918. Online ahead of print.
 
Bioactivities and industrial standardization status of Ganoderma lucidum: A comprehensive review.
Wu P, Zhang C, Yin Y, Zhang X, Li Q, Yuan L, Sun Y, Zhou S, Ying S, Wu J.
Heliyon. 2024 Aug 29;10(19):e36987. doi: 10.1016/j.heliyon.2024.e36987. eCollection 2024 Oct 15.
 
Ganoderma tsuage promotes pain sensitivity in aging mice.
Yang KN, Lin CY, Li WN, Tang CM, Pradhan J, Chao MW, Tseng CY.
Sci Rep. 2024 May 21;14(1):11536. doi: 10.1038/s41598-024-61499-0.
 
Gluten-free breadsticks with Ganoderma-fermented corncobs: technological and nutritional features.
Cappa C, Castorina G, Fiorillo G, Casiraghi MC, Rollini M, Consonni G, Erba D, Negrini N, Marti A.
J Sci Food Agric. 2025 Mar 18. doi: 10.1002/jsfa.14224. Online ahead of print.
 
Ganoderma tuberculosum Liquid Culture With Vineyard Pruning Extracts for Bioactive Composite Production With Antiproliferative Activity.
Angulo-Sanchez LT, Cruz-Félix MC, Vidal-Gutiérrez M, Torres-Moreno H, Muñoz-Bernal ÓA, Álvarez-Parrilla E, Robles-Zepeda RE, Álvarez-Bajo O, Gutiérrez A, Esqueda M.
Adv Pharmacol Pharm Sci. 2024 Oct 24;2024:5245451. doi: 10.1155/2024/5245451. eCollection 2024.
 
Potentials of Natural Antioxidants in Reducing Inflammation and Oxidative Stress in Chronic Kidney Disease.
Lee OYA, Wong ANN, Ho CY, Tse KW, Chan AZ, Leung GP, Kwan YW, Yeung MHY.
Antioxidants (Basel). 2024 Jun 20;13(6):751. doi: 10.3390/antiox13060751.
 
Ganoderma Microsporum Immunomodulatory Protein Alleviates Inflammaging and Oxidative Stress in Diabetes-Associated Periodontitis via Nrf2 Signaling Activation: An In Vitro Study.
Su NY, Ng MY, Liao HY, Liao YW, Wu M, Chao SC, Yu CC, Chang YC.
Antioxidants (Basel). 2024 Jul 8;13(7):817. doi: 10.3390/antiox13070817.
 
Effect of Ganoderma lucidum on Cisplatin-induced Nephrotoxicity and Gastrointestinal Toxicity.
Ota N, Endo S, Tatsunami R, Yamaguchi A, Wakame K, Nakata A, Sato K.
Anticancer Res. 2024 Aug;44(8):3605-3613. doi: 10.21873/anticanres.17183.
 
High molecular weight polysaccharides from Ganoderma lucidum attenuates inflammatory responses, gut microbiota, and liver metabolomic in lipopolysaccharide-induced liver injury mice.
Guo W, Liu W, Liang P, Ni L, Lv X, Fan J, Shi F.
Int J Biol Macromol. 2025 Jan;287:138400. doi: 10.1016/j.ijbiomac.2024.138400. Epub 2024 Dec 8.
 
Extraction Optimization and Bioactivity of Polysaccharides from Ganoderma leucocontextum Spores.
Peng S, Ou Y, Zhang Y, Yao H, Chen WH.
Pharmaceuticals (Basel). 2025 Feb 11;18(2):241. doi: 10.3390/ph18020241.
 
Ganonorsterone A, a norsteroid from the medicinal fungus Ganoderma lingzhi.
Du JH, Zhao X, Zhang F, Wang Y, Du K, Ding SY, Feng WS, Zhao ZZ.
J Asian Nat Prod Res. 2024 Aug;26(8):1001-1008. doi: 10.1080/10286020.2024.2340691. Epub 2024 Apr 12.
 
Monosaccharide composition, physicochemical characteristics, and prebiotic activity of purified polysaccharides from red Ganoderma mushroom prepared using ultrasonic-assisted extraction.
Chen BJ, Xia C, Wu P, Liu Y, Li J, Jiang T, Li X, Peng B, Khoo HE.
Nat Prod Res. 2024 Nov 27:1-10. doi: 10.1080/14786419.2024.2432606. Online ahead of print.
 
Structural characteristics, sugar metabolizing enzyme activity and biological activity of Ganoderma lucidum polysaccharides at different growth stages.
Ma S, Chen Y, Huang H, Pu X, Liang H, Kuang Y, Liu Y.
Sci Rep. 2025 Feb 9;15(1):4834. doi: 10.1038/s41598-025-89559-z.
 
Six new metabolites from Ganoderma lucidum-derived endophytic Trichoderma sp. GLQ02 and their anti-inflammatory activities.
Qiu XH, Cheng X, Luo Q, Ma Y.
Fitoterapia. 2025 Apr;182:106439. doi: 10.1016/j.fitote.2025.106439. Epub 2025 Feb 10.
 
Effect of Ganoderma lucidum water extract on flavor volatiles and quality characteristics of set-type yogurt.
Bao C, Yan M, Diao M, Anastasiia U, Zhang X, Zhang T.
Food Chem. 2025 Feb 1;464(Pt 2):141687. doi: 10.1016/j.foodchem.2024.141687. Epub 2024 Oct 18.
 
Mushrooms as Nutritional Powerhouses: A Review of Their Bioactive Compounds, Health Benefits, and Value-Added Products.
Singh A, Saini RK, Kumar A, Chawla P, Kaushik R.
Foods. 2025 Feb 22;14(5):741. doi: 10.3390/foods14050741.
 
The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway.
Lu Q, Shao N, Fang Z, Ouyang Z, Shen Y, Yang R, Liu H, Cai B, Wei T.
Chem Biol Interact. 2025 May 1;412:111459. doi: 10.1016/j.cbi.2025.111459. Epub 2025 Mar 5.
 
Incorporating Ganoderma lucidum extract and powder with probiotic cultures (Lactobacillus acidophilus and Bifidobacterium animalis subsp. lactis) enhanced the functional, textural, and sensory qualities of yogurt.
Atik A, Atik İ, Akarca G, Denizkara AJ.
J Food Sci Technol. 2025 Apr;62(4):787-798. doi: 10.1007/s13197-024-06068-z. Epub 2024 Aug 21.
 
Ganoderma lucidum Spore Powder Alleviates Metabolic-Associated Fatty Liver Disease by Improving Lipid Accumulation and Oxidative Stress via Autophagy.
Zhang Y, Zhou J, Yang L, Xiao H, Liu D, Kang X.
Antioxidants (Basel). 2024 Dec 9;13(12):1501. doi: 10.3390/antiox13121501.
 
Use of mushrooms as antioxidants in a lipid oxidation model under indirect and direct oxidation tests: ethanolic extracts of Ganoderma resinaceum and Phlebopus bruchii.
Mariani ME, Juncos NS, Grosso NR, Olmedo RH.
J Sci Food Agric. 2024 Aug 30;104(11):6706-6713. doi: 10.1002/jsfa.13497. Epub 2024 Apr 12.
 
Ganoderma pfeifferi Bres. and Ganoderma resinaceum Boud. as Potential Therapeutic Agents: A Comparative Study on Antiproliferative and Lipid-Lowering Properties.
Rašeta M, Kebert M, Mišković J, Kostić S, Kaišarević S, Stilinović N, Vukmirović S, Karaman M.
J Fungi (Basel). 2024 Jul 19;10(7):501. doi: 10.3390/jof10070501.
 
Ameliorative effects of Ganoderma lucidum (Reishi) on testicular tissue of rats exposed to bisphenol A.
Acısu TC, Akarsu SA, Sönmez M, Yüce A, Çeribaşı S, Cinkara SD, Kaya ŞÖ, Türk G, Gür S.
Pol J Vet Sci. 2024 Sep;27(3):459-467. doi: 10.24425/pjvs.2024.151741.
 
Evaluation of cosmetic efficacy of lychee seed fermentation liquid.
Yan Y, Fu H, Tang Y, Huang T, Zou X, Su N, Wang D, Wang C, Li M.
Bioresour Bioprocess. 2024 Oct 31;11(1):104. doi: 10.1186/s40643-024-00818-9.
 
Synthesis, characterization and MAFLD prevention potential of Ganoderma lucidum spore polysaccharide-stabilized selenium nanoparticles.
Xiao Z, Zhou J, Chen H, Chen X, Wang L, Liu D, Kang X.
nt J Biol Macromol. 2024 Dec;282(Pt 3):136962. doi: 10.1016/j.ijbiomac.2024.136962. Epub 2024 Oct 28.
 
Ganoderma lucidum polysaccharides reduce the severity of acute liver injury by improving the diversity and function of the gut microbiota.
Zhang XT, Yang Y, Ji C, Fu Y, Pu X, Xu G.
Heliyon. 2024 Aug 2;10(15):e35559. doi: 10.1016/j.heliyon.2024.e35559. eCollection 2024 Aug 15.
 
Rhizopogon luteolus and Ganoderma adspersum Extracts Inhibit Invasion through the Crosstalk between Anti-oxidant Activity and Apoptosis Induced by pAKT/Rb.
Demiray A, Karagür ER, Tel-Cayan G, Tokgün O, Akça H, Duru ME.
Anticancer Agents Med Chem. 2025 Jan 13. doi: 10.2174/0118715206349668241118104255. Online ahead of print.
 
A glucomannan from defatted Ganoderma lucidum spores: structural characterization and immunomodulatory activity via activating TLR4/MyD88/NF-kappaB signaling pathway.
Huang J, Su Y, Wang Q, Feng M, Zhang D, Yu Q, Yan C.
Int J Biol Macromol. 2025 Mar;294:139195. doi: 10.1016/j.ijbiomac.2024.139195. Epub 2024 Dec 27.
 
Potential Medicinal Fungi from Freshwater Environments as Resources of Bioactive Compounds.
Cicero I, Mirabile G, Venturella G.
J Fungi (Basel). 2025 Jan 10;11(1):54. doi: 10.3390/jof11010054.
 
Distributions of Lanostene-Derived Triterpenoids and Glucan Content in the Fruiting Bodies of the Australian Ganoderma Species.
De Oliveira Campos A, Harrison MD, Marshall DL, Strong PJ.
J Fungi (Basel). 2024 Oct 18;10(10):723. doi: 10.3390/jof10100723.
 
The Impact of Ganoderma lucidum (Curtis) P. Karst. Supplementation on the Technological, Chemical, and Quality Parameters of Wheat Bread.
Łysakowska P, Sobota A, Wirkijowska A, Zarzycki P, Blicharz-Kania A.
Foods. 2024 Sep 28;13(19):3101. doi: 10.3390/foods13193101.
 
Identification of Selected Flavonoids Extracted from Cap and Stem of Wild and Cultivated Ganoderma Species (Agaricomycetes) and Bioactivities.
Liu Y, Xia C, Chen BJ, Li X, Wu X, Ismail A, Dong X, Khoo HE.
Int J Med Mushrooms. 2025;27(6):61-79. doi: 10.1615/IntJMedMushrooms.2025058111.
 
Optimization of Fermentation Conditions in Ergothioneine Biosynthesis from Ganoderma resinaceum (Agaricomycetes) and an Evaluation of Their Inhibitory Activity on Xanthine Oxidase.
Yu YH, Ye ZW, Huang YM, Wang N, Zheng QW, Zhong JR, Chen BX, Lin JF, Guo LQ.
Int J Med Mushrooms. 2025;27(3):71-85. doi: 10.1615/IntJMedMushrooms.2024057485.
 
Polysaccharides from Ganoderma lucidum attenuate cognitive impairment in 5xFAD mice by inhibiting oxidative stress and modulating mitochondrial dynamics via the Nrf2/antioxidative axis activation.
Liu X, Li Y, Wang J, Meng T, Song L, Yang L, Yu J, Ma C.
Metab Brain Dis. 2025 Apr 14;40(4):180. doi: 10.1007/s11011-025-01601-1.
 
[UPLC-Q-TOF-MS/MS qualitative analysis and HPLC determination of triterpenoids in Ganoderma lucidum spores].
Qiao LZ, Lu CN, Liu XQ, Chen LM, Feng WH, Liang YH, Li C, Wang ZM.
Zhongguo Zhong Yao Za Zhi. 2024 Oct;49(20):5487-5496. doi: 10.19540/j.cnki.cjcmm.20240714.201.
 
One new polyketide and four new sesquiterpenes derivatives from the fungicolous fungi aspergillus nidulans LZ8 of Ganoderma lingzhi.
Zhang H, Zhou Z, Yang M, Li S, Liu X, Jin L, Shou Q, Fu H.
Fitoterapia. 2025 Jan;180:106339. doi: 10.1016/j.fitote.2024.106339. Epub 2024 Dec 8.
 
[Oscillation-static cycle cultivation enhances the synthesis of triterpenes and mycelium activity in Ganoderma lucidum].
Jiang X, Han W, Guo J, Liu Y, Xu A, Tang C, Feng J, Zhang J.
Sheng Wu Gong Cheng Xue Bao. 2024 Sep 25;40(9):3189-3200. doi: 10.13345/j.cjb.230883.
 
Enhancement of exercise-induced fatigue alleviation and liver selenium regulation through in situ nanoselenium synthesis by Lactobacillus rhamnosus cells, empowered by Ganoderma lucidum spore loading.
Shi D, Xu F, Li Y, Shang X, Liao N, Jin H, Liu G, Shao D.
J Food Sci. 2024 Nov;89(11):7992-8005. doi: 10.1111/1750-3841.17392. Epub 2024 Oct 4.
 
Comparing application methods of reishi mushroom (Ganoderma lucidum) extract in deep-fried meatballs: impact on heterocyclic aromatic amine formation.
Guzel B, Gumus D, Kizil M.
J Sci Food Agric. 2024 Aug 15;104(10):5826-5833. doi: 10.1002/jsfa.13414. Epub 2024 Mar 6.
 
Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of Ganoderma lucidum.
Xu X, Li C, Wu F, Zhao S, Chen T, You H, Lin Y, Zou X.
J Fungi (Basel). 2025 Jan 13;11(1):57. doi: 10.3390/jof11010057.
 
Supercritical carbon-oxide extracts from cultivated and wild-grown Ganoderma lucidum mushroom: differences in ergosterol and ganoderic acids content, antioxidative and enzyme inhibitory properties.
Milovanovic I, Zengin G, Maksimovic S, Tadic V.
Nat Prod Res. 2024 Jul;38(14):2522-2528. doi: 10.1080/14786419.2023.2175355. Epub 2023 Feb 6.
 
Bidirectional Solid-State Fermentation of Highland Barley by Edible Fungi to Improve Its Functional Components, Antioxidant Activity and Texture Characteristics.
Zhou X, Wang J, Shao G, Chang X, Liu Y, Xiang T, Zhu Q, Ren A, Jiang A, He Q.
Plant Foods Hum Nutr. 2024 Jun;79(2):308-315. doi: 10.1007/s11130-024-01166-x. Epub 2024 Apr 19.
 
Comparison of lignocellulosic enzymes and CAZymes between ascomycetes (Trichoderma) and basidiomycetes (Ganoderma) species: a proteomic approach.
Shankar A, Jain KK, Kuhad RC, Sharma KK.
Z Naturforsch C J Biosci. 2023 Dec 14;80(1-2):21-32. doi: 10.1515/znc-2023-0125. Print 2025 Jan 29.
 
AOX Affects the Synthesis of Polysaccharides by Regulating the Reactive Oxygen Species in Ganoderma lucidum.
Zhu R, Zhang L, Wu L, Liu J, Zhang J, Li J, Song K, Han P.
Foods. 2025 Feb 27;14(5):826. doi: 10.3390/foods14050826.
 
Ultrasound combined mechanical wall-breaking extraction of new Ganoderma leucocontextum polysaccharides and their application as a structural and functional improver in set fat-free goat yogurt production.
Li J, Miao Y, Guo C, Tang Y, Xin S, Fan Z, Su Y, Li Q.
Food Chem. 2025 Mar 15;468:142374. doi: 10.1016/j.foodchem.2024.142374. Epub 2024 Dec 6.
 
Determination of selenium-containing species, including nanoparticles, in selenium-enriched Lingzhi mushrooms.
LeBlanc KL, Kumlung T, Suárez Priede A, Kumkrong P, Junvee T, Deawtong S, Bettmer J, Montes-Bayón M, Mester Z.
Anal Bioanal Chem. 2024 May;416(11):2761-2772. doi: 10.1007/s00216-023-05031-9. Epub 2023 Nov 21.
 
Investigating the mechanism of Zn cross-linking of chitin in a mycelium-based leather substitute and its performance evaluation.
Li S, Cao S, Wang X, Zhang Y, Zhang X, Lu W, Zhu D.
Int J Biol Macromol. 2024 Sep;276(Pt 2):133954. doi: 10.1016/j.ijbiomac.2024.133954. Epub 2024 Jul 17.
 
Evaluation of in vitro pharmacological activities of medicinal mushrooms in the context of dry eye disease.
Areesanan A, Wasilewicz A, Nicolay S, Grienke U, Zimmermann-Klemd AM, Rollinger JM, Gründemann C.
Front Pharmacol. 2025 Mar 5;16:1557359. doi: 10.3389/fphar.2025.1557359. eCollection 2025.
 
Synthesis of Ganoderic Acids Loaded Zein-Chitosan Nanoparticles and Evaluation of Their Hepatoprotective Effect on Mice Given Excessive Alcohol.
Cao Y, Yang Y, Liang Z, Guo W, Lv X, Ni L, Chen Y.
Foods. 2024 Aug 29;13(17):2760. doi: 10.3390/foods13172760.
 
Ganoderma atrum polysaccharide inhibits ROS/NLRP3/pyroptosis axis by fixing mitochondrial dynamics disorder in PD-1 inhibitors-induced carditis of Lewis lung carcinoma mice.
Mu XY, Chen SB, Yang SY, Wang WS, Zhou HM, Wang YX, Chen XY, Peng XP, Li WJ.
Int J Biol Macromol. 2025 Apr 15:143163. doi: 10.1016/j.ijbiomac.2025.143163. Online ahead of print.
 
Effects of Plant Polysaccharides Combined with Boric Acid on Digestive Function, Immune Function, Harmful Gas and Heavy Metal Contents in Faeces of Fatteners.
Deng J, Zhang F, Fan H, Zheng Y, Zhao C, Ren M, Jin E, Gu Y.
Animals (Basel). 2024 May 21;14(11):1515. doi: 10.3390/ani14111515.
 
Ganoderic Acid A Prevented Osteoporosis by Modulating the PIK3CA/p-Akt/TWIST1 Signaling Pathway.
Zhao J, Fan Y, Li H, Wang C, Fan S, Sun H, Liu M.
Food Sci Nutr. 2025 Apr 14;13(4):e70177. doi: 10.1002/fsn3.70177. eCollection 2025 Apr.

COP-22 Alleviates D-Galactose-Induced Brain Aging by Attenuating Oxidative Stress, Inflammation, and Apoptosis in Mice.
Ma Y, Wang X, Li X, Chen X, Teng Z, Wang X, Yang J, Liu G.
Mol Neurobiol. 2024 Feb 12. doi: 10.1007/s12035-024-03976-1. Online ahead of print.
 
Therapeutic potential of the medicinal mushroom Ganoderma lucidum against Alzheimer's disease.
Chen XJ, Deng Z, Zhang LL, Pan Y, Fu J, Zou L, Bai Z, Xiao X, Sheng F.
Biomed Pharmacother. 2024 Mar;172:116222. doi: 10.1016/j.biopha.2024.116222. Epub 2024 Feb 3.
 
The protective effect of PL 1-3 on D-galactose-induced aging mice.
Li P, Ma Y, Wang X, Li X, Wang X, Yang J, Liu G.
Front Pharmacol. 2024 Jan 3;14:1304801. doi: 10.3389/fphar.2023.1304801. eCollection 2023.
 
Discovery of a 4-Hydroxy-3'-Trifluoromethoxy-Substituted Resveratrol Derivative as an Anti-Aging Agent.
Liang Y, Chen X, Teng Z, Wang X, Yang J, Liu G.
Molecules. 2023 Dec 22;29(1):86. doi: 10.3390/molecules29010086.
 
Ganoderma lucidum methyl ganoderate E extends lifespan and modulates aging-related indicators in Caenorhabditis elegans.
Okoro NO, Odiba AS, Han J, Osadebe PO, Omeje EO, Liao G, Liu Y, Jin C, Fang W, Liu H, Wang B.
Food Funct. 2024 Jan 22;15(2):530-542. doi: 10.1039/d3fo04166b.
 
Ganoderma lucidum: Current advancements of characteristic components and experimental progress in anti-liver fibrosis.
Peng H, Zhong L, Cheng L, Chen L, Tong R, Shi J, Bai L.
Front Pharmacol. 2023 Jan 9;13:1094405. doi: 10.3389/fphar.2022.1094405. eCollection 2022.
 
Triterpenoids and Polysaccharides from Ganoderma lucidum Improve the Histomorphology and Function of Testes in Middle-Aged Male Mice by Alleviating Oxidative Stress and Cellular Apoptosis.
Li Y, Liang W, Han Y, Zhao W, Wang S, Qin C.
Nutrients. 2022 Nov 9;14(22):4733. doi: 10.3390/nu14224733.
 
Mushroom beta-Glucan Recovered from Antler-Type Fruiting Body of Ganoderma lucidum by Enzymatic Process and Its Potential Biological Activities for Cosmeceutical Applications.
Vaithanomsat P, Boonlum N, Chaiyana W, Tima S, Anuchapreeda S, Trakunjae C, Apiwatanapiwat W, Janchai P, Boondaeng A, Nimitkeatkai H, Jarerat A.
Polymers (Basel). 2022 Oct 7;14(19):4202. doi: 10.3390/polym14194202.
 
Ganoderic acid D prevents oxidative stress-induced senescence by targeting 14-3-3ε to activate CaM/CaMKII/NRF2 signaling pathway in mesenchymal stem cells.
Yuan H, Xu Y, Luo Y, Zhang JR, Zhu XX, Xiao JH.
Aging Cell. 2022 Sep;21(9):e13686. doi: 10.1111/acel.13686. Epub 2022 Aug 5.
 
Highly oxygenated chemical constitutes and rearranged derivatives with neurotrophic activity from Ganoderma cochlear.
Yu C, Cao CY, Shi PD, Yang AA, Yang YX, Huang DS, Chen X, Chen ZM, Gao JM, Yin X.
J Ethnopharmacol. 2022 Sep 15;295:115393. doi: 10.1016/j.jep.2022.115393. Epub 2022 May 21.
 
Mushrooms as Potential Sources of Active Metabolites and Medicines.
Bhambri A, Srivastava M, Mahale VG, Mahale S, Karn SK.
Front Microbiol. 2022 Apr 26;13:837266. doi: 10.3389/fmicb.2022.837266. eCollection 2022.
 
Protective effect of Ganoderma lucidum-fermented crop extracts against hydrogen peroxide- or beta-amyloid-induced damage in human neuronal SH-SY5Y cells.
Huang CH, Liao YT, Chen CL, Tsai GJ.
BMC Complement Med Ther. 2024 Apr 5;24(1):148. doi: 10.1186/s12906-024-04409-1.
 
Use of mushrooms as antioxidants in lipid oxidation model under indirect and direct oxidation test: Ethanolic extracts of Ganoderma resinaceum and Phlebopus bruchii.
Mariani ME, Juncos NS, Grosso NR, Olmedo RH.
J Sci Food Agric. 2024 Mar 29. doi: 10.1002/jsfa.13497. Online ahead of print.
 
Biphasic Fermentation of Trapa bispinosa Shells by Ganoderma sinense and Characterization of Its Polysaccharides and Alcoholic Extract and Analysis of Their Bioactivity.
Sun X, Lei Q, Chen Q, Song D, Zhou M, Wang H, Wang L.
Molecules. 2024 Mar 11;29(6):1238. doi: 10.3390/molecules29061238.
 
Ganoderic Acid A: A Potential Natural Neuroprotective Agent for Neurological Disorders: A Review.
Ma F, Wang J, Jiang W, Luo J, Yang R, Zhang L, Han C.
Int J Med Mushrooms. 2024;26(2):11-23. doi: 10.1615/IntJMedMushrooms.2023051918.
 
Innovative prophylactic and therapeutic approaches in liver cirrhosis.
Ciovicescu LM, Clichici SV, Simedrea RA, Ciovicescu F, Lupan SC, Sabău LI, Toader AM, Mocan T.
Physiol Int. 2024 Feb 29;111(1):1-18. doi: 10.1556/2060.2024.00339. Print 2024 Mar 21.
 
Comparing application methods of reishi mushroom (Ganoderma lucidum) extract in deep-fried meatballs: impact on heterocyclic aromatic amine formation.
Guzel B, Gumus D, Kizil M.
J Sci Food Agric. 2024 Feb 26. doi: 10.1002/jsfa.13414. Online ahead of print.
 
Exploring Nutrient Profiles, Phytochemical Composition, and the Antiproliferative Activity of Ganoderma lucidum and Ganoderma leucocontextum: A Comprehensive Comparative Study.
Peng G, Xiong C, Zeng X, Jin Y, Huang W.
Foods. 2024 Feb 18;13(4):614. doi: 10.3390/foods13040614.
 
Influence of cultivation substrate on antioxidant activities and triterpenoid profiles of the fruiting body of Ganoderma lucidum.
Luo G, Pan Z, Liu Z, Cheng W, Yu T.
Front Nutr. 2024 Feb 7;11:1329579. doi: 10.3389/fnut.2024.1329579. eCollection 2024.
 
Polysaccharides extraction from Ganoderma lucidum using a ternary deep eutectic solvents of choline chloride/guaiacol/lactic acid.
Li R, Shi G, Chen L, Liu Y.
Int J Biol Macromol. 2024 Apr;263(Pt 1):130263. doi: 10.1016/j.ijbiomac.2024.130263. Epub 2024 Feb 17.
 
Ganoderma lucidum: Insight into antimicrobial and antioxidant properties with development of secondary metabolites.
Ahmad MF, A Alsayegh A, Ahmad FA, Akhtar MS, Alavudeen SS, Bantun F, Wahab S, Ahmed A, Ali M, Elbendary EY, Raposo A, Kambal N, H Abdelrahman M.
Heliyon. 2024 Feb 4;10(3):e25607. doi: 10.1016/j.heliyon.2024.e25607. eCollection 2024 Feb 15.
 
Structural characterization and anti-oxidative activity for a glycopeptide from Ganoderma lucidum fruiting body.
Luo HJ, Zhang YK, Wang SZ, Lin SQ, Wang LF, Lin ZX, Lu GD, Lin DM.
Int J Biol Macromol. 2024 Mar;261(Pt 2):129793. doi: 10.1016/j.ijbiomac.2024.129793. Epub 2024 Jan 28.
 
EFFECT OF DRY EXTRACT FROM REISHI MUSHROOMS ON THE STATE OF ANTIOXIDANT SYSTEM IN RATS WITH DMH-INDUCED COLON CARCINOGENESIS.
Herasymets I, Fira L, Medvid I, Fira D, Yasinovskyi O, Grytsyshyn L.
Wiad Lek. 2023;76(12):2632-2640. doi: 10.36740/WLek202312112.
 
Polysaccharides from Chinese herbal medicine: a review on the hepatoprotective and molecular mechanism.
Li J, Guo H, Dong Y, Yuan S, Wei X, Zhang Y, Dong L, Wang F, Bai T, Yang Y.
Chin J Nat Med. 2024 Jan;22(1):4-14. doi: 10.1016/S1875-5364(24)60558-3.
 
Bioprospecting of Selected Species of Polypore Fungi from the Western Balkans.
Kozarski M, Klaus A, Špirović-Trifunović B, Miletić S, Lazić V, Žižak Ž, Vunduk J.
Molecules. 2024 Jan 8;29(2):314. doi: 10.3390/molecules29020314.
 
Polyamines in Edible and Medicinal Fungi from Serbia: A Novel Perspective on Neuroprotective Properties.
Rašeta M, Kebert M, Mišković J, Rakić M, Kostić S, Čapelja E, Karaman M.
J Fungi (Basel). 2023 Dec 28;10(1):21. doi: 10.3390/jof10010021.
 
Medium composition optimization and characterization of polysaccharides extracted from Ganoderma boninense along with antioxidant activity.
Li QZ, Xiong C, Wong WC, Zhou LW.
Int J Biol Macromol. 2024 Mar;260(Pt 2):129528. doi: 10.1016/j.ijbiomac.2024.129528. Epub 2024 Jan 19.
 
Impact of Ganoderma lucidum fermentation on the nutritional composition, structural characterization, metabolites, and antioxidant activity of Soybean, sweet potato and Zanthoxylum pericarpium residues.
Cen Q, Fan J, Zhang R, Chen H, Hui F, Li J, Zeng X, Qin L.
Food Chem X. 2023 Dec 16;21:101078. doi: 10.1016/j.fochx.2023.101078. eCollection 2024 Mar 30.
 
Ganoderma adspersum (Ganodermataceae): Investigation of Its Secondary Metabolites and the Antioxidant, Antimicrobial, and Cytotoxic Potential of Its Extracts.
Chafouz R, Karavergou S, Tsiftsoglou OS, Maskovic P, Lazari D.
Int J Mol Sci. 2023 Dec 30;25(1):516. doi: 10.3390/ijms25010516.
 
Amylase-assisted extraction alters nutritional and physicochemical properties of polysaccharides and saponins isolated from Ganoderma spp.
Chen BJ, Liu Y, Yang K, Li X, Dong X, Guan Y, Ismail A, Khoo HE.
Food Chem X. 2023 Sep 29;20:100913. doi: 10.1016/j.fochx.2023.100913. eCollection 2023 Dec 30.
 
Exploring the anti-cancer potential of Ganoderma lucidum polysaccharides (GLPs) and their versatile role in enhancing drug delivery systems: a multifaceted approach to combat cancer.
Gao X, Homayoonfal M.
Cancer Cell Int. 2023 Dec 16;23(1):324. doi: 10.1186/s12935-023-03146-8.
 
Comparison of lignocellulosic enzymes and CAZymes between ascomycetes (Trichoderma) and basidiomycetes (Ganoderma) species: a proteomic approach.
Shankar A, Jain KK, Kuhad RC, Sharma KK.
Z Naturforsch C J Biosci. 2023 Dec 14. doi: 10.1515/znc-2023-0125. Online ahead of print.
 
Abscisic acid-mediated cytosolic Ca(2+) modulates triterpenoid accumulation of Ganoderma lucidum.
Cui M, Zhao Y, Zhang X, Zhao W.
J Zhejiang Univ Sci B. 2023 Dec 15;24(12):1174-1179. doi: 10.1631/jzus.B2300279.
 
Characterization and nutritional valorization of agricultural waste corncobs from Italian maize landraces through the growth of medicinal mushrooms.
Castorina G, Cappa C, Negrini N, Criscuoli F, Casiraghi MC, Marti A, Rollini M, Consonni G, Erba D.
Sci Rep. 2023 Nov 30;13(1):21148. doi: 10.1038/s41598-023-48252-9.
 
Natural Bio-Compounds from Ganoderma lucidum and Their Beneficial Biological Actions for Anticancer Application: A Review.
Cadar E, Negreanu-Pirjol T, Pascale C, Sirbu R, Prasacu I, Negreanu-Pirjol BS, Tomescu CL, Ionescu AM.
Antioxidants (Basel). 2023 Oct 25;12(11):1907. doi: 10.3390/antiox12111907.
 
Ganoderma Fusions with High Yield of Ergothioneine and Comparative Analysis of Its Genomics.
Xie J, Yu Y, You J, Ye Z, Zhou F, Wang N, Zhong J, Guo L, Lin J.
J Fungi (Basel). 2023 Nov 2;9(11):1072. doi: 10.3390/jof9111072.
 
Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation.
Milovanovic I, Chillon TS, Hackler J, Schomburg L, Goessler W, Lajin B.
Food Chem. 2024 Mar 30;437(Pt 1):137842. doi: 10.1016/j.foodchem.2023.137842. Epub 2023 Nov 7.
 
Characterization and Biological Studies of the Terpenoids from Ganoderma resinaceum and Serpula similis (Agaricomycetes).
Rikame TN, Ranawade PS, Mittal SPK, Barvkar VT, Borde MY, Tak RD.
Int J Med Mushrooms. 2023;25(12):15-31. doi: 10.1615/IntJMedMushrooms.2023050771.
 
Studies of Antioxidant and Cytotoxic Activity in Ready-to-Drink Wild Ganoderma Teas: An In Vitro Approach.
Ghosh S, Das S, Saha R, Acharya K.
Int J Med Mushrooms. 2023;25(11):53-63. doi: 10.1615/IntJMedMushrooms.2023050232.
 
Antioxidant Potential of Several Polypores Mushrooms from the South of France.
Maaloul A, Portillo-Lemus L, Vitou M, Rapior S, Morel S, Fons F.
Int J Med Mushrooms. 2023;25(11):1-10. doi: 10.1615/IntJMedMushrooms.2023050126.
 
Biological Activity of Ganoderma Species (Agaricomycetes) from Sonoran Desert, Mexico.
Bacallao-Escudero A, Guerrero-Germán P, Torres-Moreno H, Vidal-Gutiérrez M, López-Romero JC, Tejeda-Mansir A, Esqueda M, Robles-Zepeda RE.
Int J Med Mushrooms. 2023;25(10):65-76. doi: 10.1615/IntJMedMushrooms.2023049938.
 
Oral Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Spore Powder Ameliorates Murine Colitis by Inhibiting Key Kinases Phosphorylation in MAPK Pathway.
Zhao Y, Zhu L.
Int J Med Mushrooms. 2023;25(10):39-48. doi: 10.1615/IntJMedMushrooms.2023049699.
 
Pharmacological Activities and Safety of Ganoderma lucidum Spores: A Systematic Review.
Thuy NHL, Tu VL, Thu LNA, Giang TT, Huyen DTK, Loc DH, Tam DNH, Phat NT, Huynh HH, Truyen TTTT, Nguyen QH, Do U, Nguyen D, Dat TV, Minh LHN.
Cureus. 2023 Sep 2;15(9):e44574. doi: 10.7759/cureus.44574. eCollection 2023 Sep.
 
The medicinal mushroom Ganoderma lucidum prevents lung tumorigenesis induced by tobacco smoke carcinogens.
Shahid A, Chen M, Yeung S, Parsa C, Orlando R, Huang Y.
Front Pharmacol. 2023 Sep 6;14:1244150. doi: 10.3389/fphar.2023.1244150. eCollection 2023.
 
An antioxidative, green and safe nanofibers-based film containing pullulan, sodium hyaluronate and Ganoderma lucidum fermentation for enhanced skincare.
Liu J, Xu H, Liang H, Zhang J, Yuan H, Zhao D, Wang C.
Int J Biol Macromol. 2023 Dec 31;253(Pt 4):127047. doi: 10.1016/j.ijbiomac.2023.127047. Epub 2023 Sep 22.
 
Anti-inflammatory activity of β-glucans from different sources before and after fermentation by fecal bacteria in vitro.
Cheng J, Zhang G, Liu L, Luo J, Peng X.
J Sci Food Agric. 2024 Jan 30;104(2):1116-1131. doi: 10.1002/jsfa.12997. Epub 2023 Nov 22.
 
Ganoderic Acid A targeting leucine-rich repeat kinase 2 involved in Parkinson's disease-A computational study.
Ahmad F.
Aging Med (Milton). 2022 Dec 20;6(3):272-280. doi: 10.1002/agm2.12235. eCollection 2023 Sep.
 
Potentialities of Ganoderma lucidum extracts as functional ingredients in food formulation.
Sharif Swallah M, Bondzie-Quaye P, Wang H, Shao CS, Hua P, Alrasheed Bashir M, Benjamin Holman J, Sossah FL, Huang Q.
Food Res Int. 2023 Oct;172:113161. doi: 10.1016/j.foodres.2023.113161. Epub 2023 Jun 18.
 
Ganoderma lucidum Mycelia Mass and Bioactive Compounds Production through Grape Pomace and Cheese Whey Valorization.
Kachrimanidou V, Papadaki A, Papapostolou H, Alexandri M, Gonou-Zagou Z, Kopsahelis N.
Molecules. 2023 Aug 30;28(17):6331. doi: 10.3390/molecules28176331.
 
Increased production and anti-senescence activity of exopolysaccharides in Ganoderma lingzhi by co-overexpression of beta-1,3-glucan synthase and UDP-glucose pyrophosphorylase.
Xu YL, Yuan H, Li N, Xiao JH, Xu JW.
Int J Biol Macromol. 2023 Dec 31;253(Pt 2):126778. doi: 10.1016/j.ijbiomac.2023.126778. Epub 2023 Sep 6.
 
Immuno-physiological effects of dietary reishi mushroom powder as a source of beta-glucan on Rohu, Labeo rohita challenged with Aeromonas veronii.
Saha TK, Mariom, Rahman T, Moniruzzaman M, Min T, Hossain Z.
Sci Rep. 2023 Sep 5;13(1):14652. doi: 10.1038/s41598-023-41557-9.
 
Mapping the metabolic characteristics of probiotic-fermented Ganoderma lucidum and its protective mechanism against Cd-induced nephrotoxicity.
Dai Z, Li G, Wang X, Gao B, Gao X, Strappe P, Zhou Z.
Food Funct. 2023 Sep 19;14(18):8615-8630. doi: 10.1039/d3fo01587d.
 
Natural Products in Renal-Associated Drug Discovery.
Wruck W, Genfi AKA, Adjaye J.
Antioxidants (Basel). 2023 Aug 11;12(8):1599. doi: 10.3390/antiox12081599.
 
Preclinical pharmacokinetics-related pharmacological effects of orally administered polysaccharides from traditional Chinese medicines: A review.
Ye D, Zhao Q, Ding D, Ma BL.
Int J Biol Macromol. 2023 Dec 1;252:126484. doi: 10.1016/j.ijbiomac.2023.126484. Epub 2023 Aug 23.
 
Mixed Medicinal Mushroom Mycelia Attenuates Alzheimer's Disease Pathologies In Vitro and In Vivo.
Jeong JH, Hong GL, Jeong YG, Lee NS, Kim DK, Park JY, Park M, Kim HM, Kim YE, Yoo YC, Han SY.
Curr Issues Mol Biol. 2023 Aug 15;45(8):6775-6789. doi: 10.3390/cimb45080428.
 
Recent Advances in the Preparation, Structure, and Biological Activities of beta-Glucan from Ganoderma Species: A Review.
Zhang H, Zhang J, Liu Y, Tang C.
Foods. 2023 Aug 7;12(15):2975. doi: 10.3390/foods12152975.
 
Comparison of the dried properties of Ganoderma lucidum produced by the convective dryer and infrared dryer.
Naseri M, Movagharnejad K, Nanvakenari S.
Sci Rep. 2023 Aug 3;13(1):12636. doi: 10.1038/s41598-023-39883-z.
 
Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production-A Review.
Łysakowska P, Sobota A, Wirkijowska A.
Molecules. 2023 Jul 14;28(14):5393. doi: 10.3390/molecules28145393.
 
Ganoderma lucidum-Mediated Green Synthesis of Silver Nanoparticles with Antimicrobial Activity.
Constantin M, Răut I, Suica-Bunghez R, Firinca C, Radu N, Gurban AM, Preda S, Alexandrescu E, Doni M, Jecu L.
Materials (Basel). 2023 Jun 8;16(12):4261. doi: 10.3390/ma16124261.
 
Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.
Gariboldi MB, Marras E, Ferrario N, Vivona V, Prini P, Vignati F, Perletti G.
Int J Mol Sci. 2023 Jun 14;24(12):10120. doi: 10.3390/ijms241210120.
 
Amelioration of CCl(4)-induced oxidative stress and hepatotoxicity by Ganoderma lucidum in long evans rats.
Johra FT, Hossain S, Jain P, Bristy AT, Emran T, Ahmed R, Sharker SM, Bepari AK, Reza HM.
Sci Rep. 2023 Jun 19;13(1):9909. doi: 10.1038/s41598-023-35228-y.
 
Ganoderma lucidum polysaccharide peptides GL-PPSQ(2) alleviate intestinal ischemia-reperfusion injury via inhibiting cytotoxic neutrophil extracellular traps.
Lin D, Zhang Y, Wang S, Zhang H, Gao C, Lu F, Li M, Chen D, Lin Z, Yang B.
Int J Biol Macromol. 2023 Jul 31;244:125370. doi: 10.1016/j.ijbiomac.2023.125370. Epub 2023 Jun 16.
 
Nutritional Value and Antioxidant, Antimicrobial and Cytotoxic Activity of Wild Macrofungi.
Dávila Giraldo LR, Pérez Jaramillo CC, Méndez Arteaga JJ, Murillo-Arango W.
Microorganisms. 2023 Apr 28;11(5):1158. doi: 10.3390/microorganisms11051158.
 
Chemical Characterization and Evaluation of Antimicrobial Properties of the Wild Medicinal Mushroom Ganoderma lucidum Growing in Northern Moroccan Forests.
Erbiai EH, Amina B, Kaoutar A, Saidi R, Lamrani Z, Pinto E, Esteves da Silva JCG, Maouni A, Pinto da Silva L.
Life (Basel). 2023 May 19;13(5):1217. doi: 10.3390/life13051217.
 
Study on the Structure and Bioactivity of Ganoderma lucidum Polysaccharides under Cassava Stalk Stress.
Liu Y, Mai B, Li Z, Feng X, Chen Y, Lin L, Xia Q.
J Fungi (Basel). 2023 Apr 26;9(5):514. doi: 10.3390/jof9050514.
 
First cocrystal of esculetin: Simultaneously optimized in vitro/vivo properties and antioxidant effect.
Liu F, Li JY, Han CB, Wang JH, Tong SY, Wang XK, Li YT, Sun WJ.
Eur J Pharm Sci. 2023 Aug 1;187:106469. doi: 10.1016/j.ejps.2023.106469. Epub 2023 May 19.
 
Optimization of Triterpene Yield from Ganoderma atrum HBSD Z19 (Agaricomycetes) by Optimization of Medium Components and Evaluation of Bioactivity Under Simulated Gastrointestinal Digestion In Vitro.
Dong R, Qiao J, Song S, Zhuansun W, Hu Y, Zeng X, Xin B, Weng Q, Zeng H, Yin X.
Int J Med Mushrooms. 2023;25(5):75-90. doi: 10.1615/IntJMedMushrooms.2023048024.
 
Structural characterization of polysaccharides after fermentation from Ganoderma lucidum and its antioxidant activity in HepG2 cells induced by H(2)O(2).
Zhao Y, Li Q, Wang M, Wang Y, Piao C, Yu H, Liu J, Li Z.
Food Chem X. 2023 Apr 23;18:100682. doi: 10.1016/j.fochx.2023.100682. eCollection 2023 Jun 30.
 
Edible and medicinal mushrooms (Pleurotus ostreatus, Ustilago maydis, Ganoderma lucidum) reduce endoplasmic reticulum stress and inflammation in adipose tissue of obese Wistar rats fed with a high fat plus saccharose diet.
González-Ibáñez L, Meneses ME, Sánchez-Tapia M, Pérez-Luna D, Torres N, Torre-Villalvazo I, Bonilla M, Petlacalco B, Castillo I, López-Barradas A, Macías A, Tovar AR, Martínez-Carrera D.
Food Funct. 2023 Jun 6;14(11):5048-5061. doi: 10.1039/d3fo00089c.
 
Ganoderma lingzhi culture enhance growth performance via improvement of antioxidant activity and gut probiotic proliferation in Sanhuang broilers.
Liu X, Huang L, Shi Y, Wang X, Luo Y, Wei S, Qin Y, Lu Y, Zhang W, Ju Y, Yan Y, Liao Y.
Front Vet Sci. 2023 Apr 17;10:1143649. doi: 10.3389/fvets.2023.1143649. eCollection 2023.
 
Spore Oil-Functionalized Selenium Nanoparticles Protect Pancreatic Beta Cells from Palmitic Acid-Induced Apoptosis via Inhibition of Oxidative Stress-Mediated Apoptotic Pathways.
Zhou S, Zhu H, Xiong P, Shi L, Bai W, Li X.
Antioxidants (Basel). 2023 Mar 30;12(4):840. doi: 10.3390/antiox12040840.
 
Plaster Gel Loaded with Silver Nanoparticle-Mediated Ganoderma applanatum: from Fabrication to Evaluation.
Maneewattanapinyo P, Monton C, Pichayakorn W, Dangmanee N, Wunnakup T, Suksaeree J.
AAPS PharmSciTech. 2023 Apr 20;24(5):105. doi: 10.1208/s12249-023-02566-z.
 
Chemical Components of Volatile Oil Extracted from the Fermentation Broth of Ganoderma lingzhi (Agaricomycetes) Coupled with Its Antitumor and Antioxidant Activities In Vitro.
Wang C, Liu W, Wei Y, Guo X, Zhang J, Tang C, Feng J, Feng N, Han W.
Int J Med Mushrooms. 2023;25(4):65-73. doi: 10.1615/IntJMedMushrooms.2023047587.
 
Biosynthesis and Bioapplications of Nanomaterials from Mushroom Products.
Rai SN, Mishra D, Singh P, Singh MP, Vamanu E, Petre A.
Curr Pharm Des. 2023;29(13):1002-1008. doi: 10.2174/1381612829666230417083133.
 
Optimization of mycelial growth and cultivation of wild Ganoderma sinense.
Nguyen LT, Van Le V, Nguyen BTT, Nguyen HTT, Tran AD, Ngo NX.
BioTechnologia (Pozn). 2023 Mar 27;104(1):65-74. doi: 10.5114/bta.2023.125087. eCollection 2023.
 
Neuroprotective, neurogenic, and anticholinergic evidence of Ganoderma lucidum cognitive effects: Crucial knowledge is still lacking.
Luz DA, Pinheiro AM, Fontes-Júnior EA, Maia CSF.
Med Res Rev. 2023 Sep;43(5):1504-1536. doi: 10.1002/med.21957. Epub 2023 Apr 13.
 
Evaluating the Application Potential of a Recombinant Ganoderma Protein as Bioactive Ingredients in Cosmetics.
Guo ZJ, Liu Y, Yang JY, Jin MY, Mao PW, Zhou XW.
Molecules. 2023 Apr 6;28(7):3272. doi: 10.3390/molecules28073272.
 
Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections.
Ekiz E, Oz E, Abd El-Aty AM, Proestos C, Brennan C, Zeng M, Tomasevic I, Elobeid T, Çadırcı K, Bayrak M, Oz F.
Foods. 2023 Apr 3;12(7):1512. doi: 10.3390/foods12071512.
 
Preparation and Characterization of Multilayer pH-Responsive Hydrogel Loaded Ganoderma lucidum Peptides.
Liu R, Gan J, Du M, Kong X, Xu C, Lü Y, Cao S, Meng T, Wang B, Yu T.
Foods. 2023 Mar 31;12(7):1481. doi: 10.3390/foods12071481.
 
Effects of Mexican Ganoderma lucidum extracts on liver, kidney, and the gut microbiota of Wistar rats: A repeated dose oral toxicity study.
Meneses ME, Martínez-Carrera D, González-Ibáñez L, Torres N, Sánchez-Tapia M, Márquez-Mota CC, Rendón G, Mitzi V, Morales A, Tello-Salgado I, Tovar AR.
PLoS One. 2023 Apr 6;18(4):e0283605. doi: 10.1371/journal.pone.0283605. eCollection 2023.
 
Transcriptome analysis reveals insight into the protective effect of N-acetylcysteine against cadmium toxicity in Ganoderma lucidum (Polyporales: Polyporaceae).
Jin X, Wu P, Li P, Xiong C, Gui M, Huang W.
Environ Sci Pollut Res Int. 2023 Apr;30(20):58436-58449. doi: 10.1007/s11356-023-26635-9. Epub 2023 Mar 29.
 
Effect of Supplemental Antioxidant-Based Therapy on the Oxidative Stress Level in COVID-19 Patients.
Zendelovska D, Atanasovska E, Spasovska K, Kirijas M, Kapsarov K, Jakimovski D, Petrushevska M.
Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2023 Mar 29;44(1):7-16. doi: 10.2478/prilozi-2023-0002. Print 2023 Mar 1.
 
A proteoglycan isolated from Ganoderma lucidum attenuates diabetic kidney disease by inhibiting oxidative stress-induced renal fibrosis both in vitro and in vivo.
Pan Y, Zhang Y, Li J, Zhang Z, He Y, Zhao Q, Yang H, Zhou P.
J Ethnopharmacol. 2023 Jun 28;310:116405. doi: 10.1016/j.jep.2023.116405. Epub 2023 Mar 24.
 
Ganoderma lucidum polysaccharides improve lipid metabolism against high-fat diet-induced dyslipidemia.
Wang W, Zhang Y, Wang Z, Zhang J, Jia L.
J Ethnopharmacol. 2023 Jun 12;309:116321. doi: 10.1016/j.jep.2023.116321. Epub 2023 Mar 1.
 
A Review on the Sources, Structures, and Pharmacological Activities of Lucidenic Acids.
Zheng C, Rangsinth P, Shiu PHT, Wang W, Li R, Li J, Kwan YW, Leung GPH.
Molecules. 2023 Feb 12;28(4):1756. doi: 10.3390/molecules28041756.
 
Molecular mechanisms of the chemical constituents from anti-inflammatory and antioxidant active fractions of Ganoderma neo-japonicum Imazeki.
Zhang RR, Zhang J, Guo X, Chen YY, Sun JY, Miao JL, Carpena M, Prieto MA, Li NY, Zhou QX, Liu C.
Curr Res Food Sci. 2023 Jan 25;6:100441. doi: 10.1016/j.crfs.2023.100441. eCollection 2023.
 
Effects of glutamate oxaloacetate transaminase on reactive oxygen species in Ganoderma lucidum.
Liu H, Qiao J, Shangguan J, Zhu J.
Appl Microbiol Biotechnol. 2023 Mar;107(5-6):1845-1861. doi: 10.1007/s00253-023-12417-3. Epub 2023 Feb 9.
 
Exploring Mushroom Polysaccharides for the Development of Novel Prebiotics: A Review.
Fernandes A, Nair A, Kulkarni N, Todewale N, Jobby R.
Int J Med Mushrooms. 2023;25(2):1-10. doi: 10.1615/IntJMedMushrooms.2022046837.
 
Supercritical carbon-oxide extracts from cultivated and wild-grown Ganoderma lucidum mushroom: differences in ergosterol and ganoderic acids content, antioxidative and enzyme inhibitory properties.
Milovanovic I, Zengin G, Maksimovic S, Tadic V.
Nat Prod Res. 2023 Feb 6:1-7. doi: 10.1080/14786419.2023.2175355. Online ahead of print.
 
Therapeutic potential and nutritional significance of Ganoderma lucidum - a comprehensive review from 2010 to 2022.
Swallah MS, Bondzie-Quaye P, Wu Y, Acheampong A, Sossah FL, Elsherbiny SM, Huang Q.
Food Funct. 2023 Feb 21;14(4):1812-1838. doi: 10.1039/d2fo01683d.
 
Immunomodulatory effects and mechanisms of Tiepishihu Xiyangshen granules on cyclophosphamide induced immuno-suppression via TLR4/MAPKs and PI3K/AKT/FOXO3a signal pathways.
Hu N, Qu Y, Liu TY, Zhou Y, Liu C, Wang JH, Yang BF, Li CL.
J Ethnopharmacol. 2023 May 10;307:116192. doi: 10.1016/j.jep.2023.116192. Epub 2023 Jan 25.
 
AGA induces sub-G1 cell cycle arrest and apoptosis in human colon cancer cells through p53-independent/p53-dependent pathway.
Peng BY, Singh AK, Chan CH, Deng YH, Li PY, Su CW, Wu CY, Deng WP.
BMC Cancer. 2023 Jan 2;23(1):1. doi: 10.1186/s12885-022-10466-x.
 
A novel promising neuroprotective agent: Ganoderma lucidum polysaccharide.
Liu X, Yang L, Li G, Jiang Y, Zhang G, Ling J.
Int J Biol Macromol. 2023 Feb 28;229:168-180. doi: 10.1016/j.ijbiomac.2022.12.276. Epub 2022 Dec 29.
 
Physiological changes and gene responses during Ganoderma lucidum growth with selenium supplementation.
Zhang B, Tan W, Zhou J, Ye L, Jia D, Li X.
PeerJ. 2022 Dec 20;10:e14488. doi: 10.7717/peerj.14488. eCollection 2022.
 
Fungal-Modified Lignin-Enhanced Physicochemical Properties of Collagen-Based Composite Films.
Tunuhe A, Liu P, Ullah M, Sun S, Xie H, Ma F, Yu H, Zhou Y, Xie S.
J Fungi (Basel). 2022 Dec 16;8(12):1303. doi: 10.3390/jof8121303.
 
Anticancer and Antioxidant Activity of Water-Soluble Polysaccharides from Ganoderma aff. australe against Human Osteosarcoma Cells.
Muñoz-Castiblanco T, Santa Maria de la Parra L, Peña-Cañón R, Mejía-Giraldo JC, León IE, Puertas-Mejía MÁ.
Int J Mol Sci. 2022 Nov 26;23(23):14807. doi: 10.3390/ijms232314807.
 
The chemical profiling and assessment of antioxidative, antidiabetic and antineurodegenerative potential of Kombucha fermented Camellia sinensis, Coffea arabica and Ganoderma lucidum extracts.
Pavlović MO, Stajić M, Gašić U, Duletić-Laušević S, Ćilerdžić J.
Food Funct. 2023 Jan 3;14(1):262-276. doi: 10.1039/d2fo02979k.
 
Amelioration effect of water extract from Ganoderma resinaceum FQ23 solid-state fermentation fungal substance with high-yield ergothioneine on anxiety-like insomnia mice.
Huang JH, Li Y, Zhang S, Zou Y, Zheng QW, Lin JF, Guo LQ.
Food Funct. 2022 Dec 13;13(24):12925-12937. doi: 10.1039/d2fo01847k.
 
Antioxidative and Cytoprotective Effects of Ganoderma applanatum and Fomitopsis pinicola in PC12 Adrenal Phaeochromocytoma Cells.
Li XY, Li SY, Yin F, Chen HM, Yang DF, Liu XQ, Jin QH, Lv XM, Mans D, Zhang XD, Liang ZS.
Int J Med Mushrooms. 2022;24(10):15-29. doi: 10.1615/IntJMedMushrooms.2022045050.
 
Christensenella regulated by Huang-Qi-Ling-Hua-San is a key factor by which to improve type 2 diabetes.
Pan T, Zheng S, Zheng W, Shi C, Ning K, Zhang Q, Xie Y, Xiang H, Xie Q.
Front Microbiol. 2022 Oct 12;13:1022403. doi: 10.3389/fmicb.2022.1022403. eCollection 2022.
 
Investigating the cellular antioxidant and anti-inflammatory effects of the novel peptides in lingzhi mushrooms.
Aursuwanna T, Noitang S, Sangtanoo P, Srimongkol P, Saisavoey T, Puthong S, Reamtong O, Karnchanatat A.
Heliyon. 2022 Oct 13;8(10):e11067. doi: 10.1016/j.heliyon.2022.e11067. eCollection 2022 Oct.
 
Nephroprotective Effects of Two Ganoderma Species Methanolic Extracts in an In Vitro Model of Cisplatin Induced Tubulotoxicity.
Sinaeve S, Husson C, Antoine MH, Welti S, Stévigny C, Nortier J.
J Fungi (Basel). 2022 Sep 24;8(10):1002. doi: 10.3390/jof8101002.
 
Two Laminaria japonica Fermentation Broths Alleviate Oxidative Stress and Inflammatory Response Caused by UVB Damage: Photoprotective and Reparative Effects.
Sun Q, Fang J, Wang Z, Song Z, Geng J, Wang D, Wang C, Li M.
Mar Drugs. 2022 Oct 20;20(10):650. doi: 10.3390/md20100650.
 
Fungi composition in settled dust associated with fractional exhaled nitric oxide in school children with asthma.
Isa KNM, Jalaludin J, Hashim Z, Than LTL, Hashim JH, Norbäck D.
Sci Total Environ. 2022 Dec 20;853:158639. doi: 10.1016/j.scitotenv.2022.158639. Epub 2022 Sep 9.
 
Ganoderma lucidum: Unutilized natural medicine and promising future solution to emerging diseases in Africa.
Oke MA, Afolabi FJ, Oyeleke OO, Kilani TA, Adeosun AR, Olanbiwoninu AA, Adebayo EA.
Front Pharmacol. 2022 Aug 22;13:952027. doi: 10.3389/fphar.2022.952027. eCollection 2022.
 
Alkaloids, sesquiterpenoids and hybrids of terpenoid with p-hydroxycinnamic acid from Ganoderma sinensis and their biological evaluation.
Luo Q, Cao WW, Cheng YX.
Phytochemistry. 2022 Nov;203:113379. doi: 10.1016/j.phytochem.2022.113379. Epub 2022 Aug 25.
 
Assessment of Cosmetic Properties and Safety of Use of Model Washing Gels with Reishi, Maitake and Lion's Mane Extracts.
Ziemlewska A, Wójciak M, Mroziak-Lal K, Zagórska-Dziok M, Bujak T, Nizioł-Łukaszewska Z, Szczepanek D, Sowa I.
Molecules. 2022 Aug 10;27(16):5090. doi: 10.3390/molecules27165090.
 
Anticancer and Antioxidant Activities in Ganoderma lucidum Wild Mushrooms in Poland, as Well as Their Phenolic and Triterpenoid Compounds.
Kolniak-Ostek J, Oszmiański J, Szyjka A, Moreira H, Barg E.
Int J Mol Sci. 2022 Aug 19;23(16):9359. doi: 10.3390/ijms23169359.
 
Comparison of the Anti-Inflammatory and Antioxidant Activities of Mycelial Polysaccharides from Different Strains of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).
Zhang J, Shi X, Cheng W, Wang Q, Wang C, Li M, Zhao D, An Q.
Int J Med Mushrooms. 2022;24(7):77-90. doi: 10.1615/IntJMedMushrooms.2022044274.
 
Antioxidant Properties of Triterpenoids Isolated from Bagasse-Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), at Different Developmental Stages.
Huang Q, Wang L, Zhang L, Hu B, Wang Q, Liang L.
Int J Med Mushrooms. 2022;24(7):41-51. doi: 10.1615/IntJMedMushrooms.2022044188.
 
Immunomodulatory effect of Ganoderma lucidum polysaccharide extract on peritoneal macrophage function of BALB/c mice.
Hu Y, Lin Z, Fu H, Xia J, Xiong W, Li G.
Cell Mol Biol (Noisy-le-grand). 2022 Apr 30;68(4):31-34. doi: 10.14715/cmb/2022.68.4.4.
 
Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.
Huang P, Luo FJ, Ma YC, Wang SX, Huang J, Qin DD, Xue FF, Liu BY, Wu Q, Wang XL, Liu GQ.
Food Funct. 2022 Aug 30;13(17):9032-9048. doi: 10.1039/d2fo01572b.
 
Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview.
Cör Andrejč D, Knez Ž, Knez Marevci M.
Front Pharmacol. 2022 Jul 22;13:934982. doi: 10.3389/fphar.2022.934982. eCollection 2022.
 
Mushroom-Derived Novel Selenium Nanocomposites' Effects on Potato Plant Growth and Tuber Germination.
Tsivileva OM, Perfileva AI.
Molecules. 2022 Jul 11;27(14):4438. doi: 10.3390/molecules27144438.
 
Evaluation of the Use of Elicitors for the Production of Antioxidant Compounds in Liquid Cultures of Ganoderma curtisii from Costa Rica.
Rosales-López C, Arce-Torres F, Monge-Artavia M, Rojas-Chaves M.
Molecules. 2022 Jul 2;27(13):4265. doi: 10.3390/molecules27134265.
 
Hypouricemic effect of 2,4-dihydroxybenzoic acid methyl ester in hyperuricemic mice through inhibiting XOD and down-regulating URAT1.
Yong T, Liang D, Xiao C, Huang L, Chen S, Xie Y, Gao X, Wu Q, Hu H, Li X, Liu Y, Cai M.
Biomed Pharmacother. 2022 Sep;153:113303. doi: 10.1016/j.biopha.2022.113303. Epub 2022 Jun 21.
 
Discovery of a Multifunctional Octapeptide from Lingzhi with Antioxidant and Tyrosinase Inhibitory Activity.
Yingchutrakul Y, Krobthong S, Choowongkomon K, Papan P, Samutrtai P, Mahatnirunkul T, Chomtong T, Srimongkolpithak N, Jaroenchuensiri T, Aonbangkhen C.
Pharmaceuticals (Basel). 2022 May 30;15(6):684. doi: 10.3390/ph15060684.
 
Ganoderma lucidum Modulates Glucose, Lipid Peroxidation and Hepatic Metabolism in Streptozotocin-Induced Diabetic Pregnant Rats.
Viroel FJM, Laurino LF, Caetano ÉLA, Jozala AF, Spim SRV, Pickler TB, Sercundes MK, Gomes MC, Hataka A, Grotto D, Gerenutti M.
Antioxidants (Basel). 2022 May 24;11(6):1035. doi: 10.3390/antiox11061035.
 
Unified Total Synthesis of Diverse Meroterpenoids from Ganoderma Applanatum.
Šimek M, Bártová K, Issad S, Hájek M, Císařová I, Jahn U.
Org Lett. 2022 Jul 1;24(25):4552-4556. doi: 10.1021/acs.orglett.2c01633. Epub 2022 Jun 19.
 
Production Ganoderma lucidum extract nanoparticles by expansion of supercritical fluid solution and evaluation of the antioxidant ability.
Karimi M, Raofie F, Karimi M.
Sci Rep. 2022 Jun 14;12(1):9904. doi: 10.1038/s41598-022-13727-8.
 
Immunomodulatory protein from ganoderma microsporum protects against oxidative damages and cognitive impairments after traumatic brain injury.
Chao MW, Liao CW, Lin CH, Tseng CY.
Mol Cell Neurosci. 2022 May;120:103735. doi: 10.1016/j.mcn.2022.103735. Epub 2022 May 11.
 
Polysaccharide prediction in Ganoderma lucidum fruiting body by hyperspectral imaging.
Liu Y, Long Y, Liu H, Lan Y, Long T, Kuang R, Wang Y, Zhao J.
Food Chem X. 2021 Dec 29;13:100199. doi: 10.1016/j.fochx.2021.100199. eCollection 2022 Mar 30.
 
Polysaccharide-Rich Fractions from Ganoderma resinaceum (Ganodermataceae) as Chemopreventive Agents in N-Diethylnitrosamine-Induced Hepatocellular Carcinoma in Wistar Rats.
Sipping MTK, Mediesse FK, Kenmogne LV, Kanemoto JEN, Njamen D, Boudjeko T.
Evid Based Complement Alternat Med. 2022 Apr 12;2022:8198859. doi: 10.1155/2022/8198859. eCollection 2022.
 
Polysaccharide-Protein Complex Isolated from Fruiting Bodies and Cultured Mycelia of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Attenuates Doxorubicin-Induced Oxidative Stress and Myocardial Injury in Rats.
Veena RK, Janardhanan KK.
Int J Med Mushrooms. 2022;24(2):31-40. doi: 10.1615/IntJMedMushrooms.2022042125.

Ganoderma tsugae prevents cognitive impairment and attenuates oxidative damage in d-galactose-induced aging in the rat brain.
Kuo HC, Tong SY, Chao MW, Tseng CY.
PLoS One. 2022 Apr 7;17(4):e0266331. doi: 10.1371/journal.pone.0266331. eCollection 2022.
 
Ganoderma lucidum aqueous extract inducing PHGPx to inhibite membrane lipid hydroperoxides and regulate oxidative stress based on single-cell animal transcriptome.
Ding W, Zhang X, Yin X, Zhang Q, Wang Y, Guo C, Chen Y.
Sci Rep. 2022 Feb 24;12(1):3139. doi: 10.1038/s41598-022-06985-z.
 
Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice.
Zeng M, Qi L, Guo Y, Zhu X, Tang X, Yong T, Xie Y, Wu Q, Zhang M, Chen D.
Front Aging Neurosci. 2021 May 6;13:628860. doi: 10.3389/fnagi.2021.628860. eCollection 2021.
 
Polysaccharides, Next Potential Agent for the Treatment of Epilepsy?
Xie X, Wu Y, Xie H, Wang H, Zhang X, Yu J, Zhu S, Zhao J, Sui L, Li S.
Front Pharmacol. 2022 Mar 18;13:790136. doi: 10.3389/fphar.2022.790136. eCollection 2022.
 
Gastroprotective Effects of Ganoderma lucidum Polysaccharides with Different Molecular Weights on Ethanol-Induced Acute Gastric Injury in Rats.
Tian B, Zhao Q, Xing H, Xu J, Li Z, Zhu H, Yang K, Sun P, Cai M.
Nutrients. 2022 Apr 1;14(7):1476. doi: 10.3390/nu14071476.
 
Inhibition on α-Glucosidase Activity and Non-Enzymatic Glycation by an Anti-Oxidative Proteoglycan from Ganoderma lucidum.
Zhang Y, Pan Y, Li J, Zhang Z, He Y, Yang H, Zhou P.
Molecules. 2022 Feb 22;27(5):1457. doi: 10.3390/molecules27051457.
 
Triterpenoids and meroterpenoids from the edible Ganoderma resinaceum and their potential anti-inflammatory, antioxidant and anti-apoptosis activities.
Kou RW, Xia B, Wang ZJ, Li JN, Yang JR, Gao YQ, Yin X, Gao JM.
Bioorg Chem. 2022 Apr;121:105689. doi: 10.1016/j.bioorg.2022.105689. Epub 2022 Feb 21.
 
A Research on Quality Evaluation of Eight Wild Edible Macrofungi Collected from East Mediterranean Region of Turkey.
Kıvrık M, Süfer Ö, Bozok F.
Chem Biodivers. 2022 Mar;19(3):e202100967. doi: 10.1002/cbdv.202100967. Epub 2022 Feb 22.
 
Comparison of the healing effects of mesazaline and Ganoderma lucidum in acetic acid-induced colitis in rats.
Özden H, Şahin Y, Kilitçi A, Karaca G, Gömeç M, Yildiz A, Uçar C.
Ann Surg Treat Res. 2022 Jan;102(1):29-35. doi: 10.4174/astr.2022.102.1.29. Epub 2022 Jan 3.
 
Antioxidation of a proteoglycan from Ganoderma lucidum protects pancreatic β-cells against oxidative stress-induced apoptosis in vitro and in vivo.
Pan Y, Yuan S, Teng Y, Zhang Z, He Y, Zhang Y, Liang H, Wu X, Li J, Yang H, Zhou P.
Int J Biol Macromol. 2022 Mar 1;200:470-486. doi: 10.1016/j.ijbiomac.2022.01.044. Epub 2022 Jan 19.
 
Profiling of phytochemical and antioxidant activity of wild mushrooms: Evidence from the in vitro study and phytoconstituent's binding affinity to the human erythrocyte catalase and human glutathione reductase.
Hossen SMM, Hossain MS, Yusuf ATM, Chaudhary P, Emon NU, Janmeda P.
Food Sci Nutr. 2021 Nov 2;10(1):88-102. doi: 10.1002/fsn3.2650. eCollection 2022 Jan.
 
Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress.
Zhang Q, Liu J, Duan H, Li R, Peng W, Wu C.
J Adv Res. 2021 Jul 6;34:43-63. doi: 10.1016/j.jare.2021.06.023. eCollection 2021 Dec.
 
GSNOR regulates ganoderic acid content in Ganoderma lucidum under heat stress through S-nitrosylation of catalase.
Liu R, Zhu T, Chen X, Wang Z, Yang Z, Ren A, Shi L, Yu H, Zhao M.
Commun Biol. 2022 Jan 11;5(1):32. doi: 10.1038/s42003-021-02988-0.
 
Bioactivity and Mycochemical Profile of Extracts from Mycelial Cultures of Ganoderma spp.
Sułkowska-Ziaja K, Zengin G, Gunia-Krzyżak A, Popiół J, Szewczyk A, Jaszek M, Rogalski J, Muszyńska B.
Molecules. 2022 Jan 3;27(1):275. doi: 10.3390/molecules27010275.
 
The Pharmacological Rationales and Molecular Mechanisms of Ganoderma lucidum Polysaccharides for the Therapeutic Applications of Multiple Diseases.
Luo H, Tan D, Peng B, Zhang S, Vong CT, Yang Z, Wang Y, Lin Z.
Am J Chin Med. 2022;50(1):53-90. doi: 10.1142/S0192415X22500033. Epub 2021 Dec 28.
 
Transcription factor GlbHLH regulates hyphal growth, stress resistance, and polysaccharide biosynthesis in Ganoderma lucidum.
Yang Y, Zhang Y, He J, Wu Q, Li Y, Li W, Zhou G, Kamol R, Yang X.
J Basic Microbiol. 2022 Jan;62(1):82-91. doi: 10.1002/jobm.202100334. Epub 2021 Dec 20.
 
A polysaccharide isolated from Ganoderma lucidum ameliorates hyperglycemia through modulating gut microbiota in type 2 diabetic mice.
Shao W, Xiao C, Yong T, Zhang Y, Hu H, Xie T, Liu R, Huang L, Li X, Xie Y, Zhang J, Chen S, Cai M, Chen D, Liu Y, Gao X, Wu Q.
Int J Biol Macromol. 2022 Feb 1;197:23-38. doi: 10.1016/j.ijbiomac.2021.12.034. Epub 2021 Dec 15.
 
Self-nanoemulsifying composition containing curcumin, quercetin, Ganoderma lucidum extract powder and probiotics for effective treatment of type 2 diabetes mellitus in streptozotocin induced rats.
Khursheed R, Singh SK, Kumar B, Wadhwa S, Gulati M, A A, Awasthi A, Vishwas S, Kaur J, Corrie L, K R A, Kumar R, Jha NK, Gupta PK, Zacconi F, Dua K, Chitranshi N, Mustafa G, Kumar A.
Int J Pharm. 2022 Jan 25;612:121306. doi: 10.1016/j.ijpharm.2021.121306. Epub 2021 Nov 20.
 
Novelkaraya gum micro-particles loaded Ganoderma lucidum polysaccharide regulate sex hormones, oxidative stress and inflammatory cytokine levels in cadmium induced testicular toxicity in experimental animals.
Bin-Jumah MN, Nadeem MS, Gilani SJ, Imam SS, Alshehri S, Kazmi I.
Int J Biol Macromol. 2022 Jan 1;194:338-346. doi: 10.1016/j.ijbiomac.2021.11.072. Epub 2021 Nov 18.
 
Exploring the Protective and Reparative Mechanisms of G. lucidum Polysaccharides Against H2O2-Induced Oxidative Stress in Human Skin Fibroblasts.
Shi X, Cheng W, Wang Q, Zhang J, Wang C, Li M, Zhao D, Wang D, An Q.
Clin Cosmet Investig Dermatol. 2021 Oct 14;14:1481-1496. doi: 10.2147/CCID.S334527. eCollection 2021.
 
Optimization of Growth Conditions and Biological Activities of Nepalese Ganoderma lucidum Strain Philippine.
Subedi K, Basnet BB, Panday R, Neupane M, Tripathi GR.
Adv Pharmacol Pharm Sci. 2021 Oct 4;2021:4888979. doi: 10.1155/2021/4888979. eCollection 2021.
 
Ganoderic Acids Prevent Renal Ischemia Reperfusion Injury by Inhibiting Inflammation and Apoptosis.
Shao G, He J, Meng J, Ma A, Geng X, Zhang S, Qiu Z, Lin D, Li M, Zhou H, Lin S, Yang B.
Int J Mol Sci. 2021 Sep 23;22(19):10229. doi: 10.3390/ijms221910229.
 
Co-encapsulation of probiotic Lactobacillus acidophilus and Reishi medicinal mushroom (Ganoderma lingzhi) extract in moist calcium alginate beads.
Mirmazloum I, Ladányi M, Omran M, Papp V, Ronkainen VP, Pónya Z, Papp I, Némedi E, Kiss A.
Int J Biol Macromol. 2021 Dec 1;192:461-470. doi: 10.1016/j.ijbiomac.2021.09.177. Epub 2021 Oct 1.
 
Bioactive Compounds and Antioxidant Activity of Four Native Species of the Ganodermataceae Family (Agaricomycetes) from Paraguay.
Campi M, Mancuello C, Ferreira F, Maubet Y, Cristaldo E, Robledo G.
Int J Med Mushrooms. 2021;23(8):65-76. doi: 10.1615/IntJMedMushrooms.2021039298.
 
Effect of Continuous Cropping Soil on the Biosynthesis of Bioactive Compounds and the Antioxidant Activity of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).
Chen Z, Xu J, Xu H, Li S, Li C, Wang Q, Yang M, Wang H, Zheng B, Wu X.
Int J Med Mushrooms. 2021;23(8):25-37. doi: 10.1615/IntJMedMushrooms.2021039536.
 
Heat Treatment of Reishi Medicinal Mushroom (Ganoderma lingzhi) Basidiocarp Enhanced Its β-glucan Solubility, Antioxidant Capacity and Lactogenic Properties.
Kiss A, Grünvald P, Ladányi M, Papp V, Papp I, Némedi E, Mirmazloum I.
Foods. 2021 Aug 27;10(9):2015. doi: 10.3390/foods10092015.
 
The non-canonical functions of telomerase reverse transcriptase gene GlTert on regulating fungal growth, oxidative stress, and ganoderic acid biosynthesis in Ganoderma lucidum.
Zhang G, Zhang C, Leng D, Yan P, Wang Z, Zhang M, Wu Z.
Appl Microbiol Biotechnol. 2021 Oct;105(19):7353-7365. doi: 10.1007/s00253-021-11564-9. Epub 2021 Sep 13.
 
Purification and comparative study of bioactivities of a natural selenized polysaccharide from Ganoderma Lucidum mycelia.
Dong Z, Dong G, Lai F, Wu H, Zhan Q.
Int J Biol Macromol. 2021 Nov 1;190:101-112. doi: 10.1016/j.ijbiomac.2021.08.189. Epub 2021 Aug 31.
 
The beneficial effects of Ganoderma lucidum on cardiovascular and metabolic disease risk.
Chan SW, Tomlinson B, Chan P, Lam CWK.
Pharm Biol. 2021 Dec;59(1):1161-1171. doi: 10.1080/13880209.2021.1969413.
 
Development of mushroom polysaccharide and probiotics based solid self-nanoemulsifying drug delivery system loaded with curcumin and quercetin to improve their dissolution rate and permeability: State of the art.
Khursheed R, Singh SK, Wadhwa S, Gulati M, Kapoor B, Jain SK, Gowthamarajan K, Zacconi F, Chellappan DK, Gupta G, Jha NK, Gupta PK, Dua K.
Int J Biol Macromol. 2021 Oct 31;189:744-757. doi: 10.1016/j.ijbiomac.2021.08.170. Epub 2021 Aug 28.
 
Health-Promoting of Polysaccharides Extracted from Ganoderma lucidum.
Seweryn E, Ziała A, Gamian A.
Nutrients. 2021 Aug 7;13(8):2725. doi: 10.3390/nu13082725.
 
Effects of Efficient Expression of Vitreoscilla Hemoglobin on Production, Monosaccharide Composition, and Antioxidant Activity of Exopolysaccharides in Ganoderma lucidum.
Wang ZX, Li N, Xu JW.
Microorganisms. 2021 Jul 21;9(8):1551. doi: 10.3390/microorganisms9081551.
 
Differences in Antioxidants, Polyphenols, Protein Digestibility and Nutritional Profile between Ganoderma lingzhi from Industrial Crops in Asia and Ganoderma lucidum from Cultivation and Iberian Origin.
Fraile-Fabero R, Ozcariz-Fermoselle MV, Oria-de-Rueda-Salgueiro JA, Garcia-Recio V, Cordoba-Diaz D, Del P Jiménez-López M, Girbés-Juan T.
Foods. 2021 Jul 29;10(8):1750. doi: 10.3390/foods10081750.
 
Antioxidant Activity and Phenolic Content of Extracts of Wild Algerian Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).
Kebaili FF, Tahar N, Esseddik TM, Redouane R, Chawki B, Pablo A, Massimiliano P.
Int J Med Mushrooms. 2021;23(6):79-88. doi: 10.1615/IntJMedMushrooms.2021038424.
 
Purification, Physicochemical Properties, and Antioxidant Activities of Two Low-Molecular-Weight Polysaccharides from Ganoderma leucocontextum Fruiting Bodies.
Gao X, Qi J, Ho CT, Li B, Xie Y, Chen S, Hu H, Chen Z, Wu Q.
Antioxidants (Basel). 2021 Jul 20;10(7):1145. doi: 10.3390/antiox10071145.
 
Valorisation of biomass and diaper waste into a sustainable production of the medical mushroom Lingzhi Ganoderma lucidum.
Khoo SC, Ma NL, Peng WX, Ng KK, Goh MS, Chen HL, Tan SH, Lee CH, Luang-In V, Sonne C.
Chemosphere. 2022 Jan;286(Pt 1):131477. doi: 10.1016/j.chemosphere.2021.131477. Epub 2021 Jul 10.
 
Water Extract of Mixed Mushroom Mycelia Grown on a Solid Barley Medium Is Protective against Experimental Focal Cerebral Ischemia.
Jeong JH, Kim SH, Park MN, Park JY, Park HY, Song CE, Moon JH, Choi A, Kim KD, Lee NS, Jeong YG, Kim DK, Lee BH, Yoo YC, Han SY.
Curr Issues Mol Biol. 2021 Jun 15;43(1):365-383. doi: 10.3390/cimb43010030.
 
Ganoderma lucidum: A potential source to surmount viral infections through β-glucans immunomodulatory and triterpenoids antiviral properties.
Ahmad MF, Ahmad FA, Khan MI, Alsayegh AA, Wahab S, Alam MI, Ahmed F.
Int J Biol Macromol. 2021 Sep 30;187:769-779. doi: 10.1016/j.ijbiomac.2021.06.122. Epub 2021 Jun 29.
 
Antiproliferative and antibacterial activity of extracts of Ganoderma strains grown in vitro.
Serrano-Márquez L, Trigos Á, Couttolenc A, Padrón JM, Shnyreva AV, Mendoza G.
Food Sci Biotechnol. 2021 May 5;30(5):711-721. doi: 10.1007/s10068-021-00903-1. eCollection 2021 May.
 
Anti-oxidant, anti-inflammatory and anti-fibrosis effects of ganoderic acid A on carbon tetrachloride induced nephrotoxicity by regulating the Trx/TrxR and JAK/ROCK pathway.
Ma JQ, Zhang YJ, Tian ZK.
Chem Biol Interact. 2021 Aug 1;344:109529. doi: 10.1016/j.cbi.2021.109529. Epub 2021 May 23.
 
Exploring role of polysaccharides present in Ganoderma lucidium extract powder and probiotics as solid carriers in development of liquisolid formulation loaded with quercetin: A novel study.
Khursheed R, Singh SK, Gulati M, Wadhwa S, Kapoor B, Pandey NK, Chellappan DK, Gupta G, Jha NK, Dua K, Kapoor DN, Karri VVSR, Pattanayak P, Sharni A, Mondal S.
Int J Biol Macromol. 2021 Jul 31;183:1630-1639. doi: 10.1016/j.ijbiomac.2021.05.064. Epub 2021 May 17.
 
Ganoderma lucidum triterpenoids and polysaccharides attenuate atherosclerotic plaque in high-fat diet rabbits.
Li Y, Tang J, Gao H, Xu Y, Han Y, Shang H, Lu Y, Qin C.
Nutr Metab Cardiovasc Dis. 2021 Jun 7;31(6):1929-1938. doi: 10.1016/j.numecd.2021.03.023. Epub 2021
 
Structural characterization and amelioration of sulfated polysaccharides from Ganoderma applanatum residue against CCl4-induced hepatotoxicity.
Song X, Cui W, Gao Z, Zhang J, Jia L.
Int Immunopharmacol. 2021 Jul;96:107554. doi: 10.1016/j.intimp.2021.107554. Epub 2021 Mar 31.
 
Effects of Ganoderma lucidum Polysaccharides on Different Pathways Involved in the Development of Spinal Cord Ischemia Reperfusion Injury: Biochemical, Histopathologic, and Ultrastructural Analysis in a Rat Model.
Kahveci R, Kahveci FO, Gokce EC, Gokce A, Kısa Ü, Sargon MF, Fesli R, Gürer B.
World Neurosurg. 2021 Jun;150:e287-e297. doi: 10.1016/j.wneu.2021.02.129. Epub 2021 Mar 6.
 
Anti-inflammatory effects of Ganoderma lucidum sterols via attenuation of the p38 MAPK and NF-κB pathways in LPS-induced RAW 264.7 macrophages.
Xu J, Xiao C, Xu H, Yang S, Chen Z, Wang H, Zheng B, Mao B, Wu X.
Food Chem Toxicol. 2021 Apr;150:112073. doi: 10.1016/j.fct.2021.112073. Epub 2021 Feb 22.
 
Utilization of Response Surface Methodology in Optimization of Polysaccharides Extraction from Vietnamese Red Ganoderma lucidum by Ultrasound-Assisted Enzymatic Method and Examination of Bioactivities of the Extract.
Do DT, Lam DH, Nguyen T, Phuong Mai TT, Phan LTM, Vuong HT, Nguyen DV, Linh NTT, Hoang MN, Mai TP, Nguyen HH.
ScientificWorldJournal. 2021 Feb 11;2021:7594092. doi: 10.1155/2021/7594092. eCollection 2021.
 
Mycelial culture extracts of selected wood-decay mushrooms as a source of skin-protecting factors.
Sułkowska-Ziaja K, Grabowska K, Apola A, Kryczyk-Poprawa A, Muszyńska B.
Biotechnol Lett. 2021 May;43(5):1051-1061. doi: 10.1007/s10529-021-03095-0. Epub 2021 Feb 23.
 
G. sinense and P. notoginseng Extracts Improve Healthspan of Aging Flies and Provide Protection in A Huntington Disease Model.
Teseo S, Houot B, Yang K, Monnier V, Liu G, Tricoire H.
Aging Dis. 2021 Apr 1;12(2):425-440. doi: 10.14336/AD.2020.0714-1. eCollection 2021 Apr.
 
Ganoderma lucidum Rhodiola compound preparation prevent D-galactose-induced immune impairment and oxidative stress in aging rat model.
Yuan S, Yang Y, Li J, Tan X, Cao Y, Li S, Hong HD, Liu L, Zhang Q.
Sci Rep. 2020 Nov 6;10(1):19244. doi: 10.1038/s41598-020-76249-1.
 
The effect of Ganoderma lucidum spore oil in early skin wound healing: interactions of skin microbiota and inflammation.
Jiao C, Xie Y, Yun H, Liang H, He C, Jiang A, Wu Q, Yang BB.
Aging (Albany NY). 2020 Jul 21;12(14):14125-14140. doi: 10.18632/aging.103412. Epub 2020 Jul 21.
 
Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.
Wong JH, Ng TB, Chan HHL, Liu Q, Man GCW, Zhang CZ, Guan S, Ng CCW, Fang EF, Wang H, Liu F, Ye X, Rolka K, Naude R, Zhao S, Sha O, Li C, Xia L.
Appl Microbiol Biotechnol. 2020 Jun;104(11):4675-4703. doi: 10.1007/s00253-020-10476-4. Epub 2020 Apr 9.
 
Herbal Medicine for Slowing Aging and Aging-associated Conditions: Efficacy, Mechanisms and Safety.
Phu HT, Thuan DTB, Nguyen THD, Posadino AM, Eid AH, Pintus G.
Curr Vasc Pharmacol. 2020;18(4):369-393. doi: 10.2174/1570161117666190715121939.
 
GCN4 regulates secondary metabolism through activating antioxidant genes expression under nitrogen limitation in Ganoderma lucidum.
Lian L, Wang L, Song S, Zhu J, Liu R, Shi L, Ren A, Zhao M.
Appl Environ Microbiol. 2021 May 7:AEM.00156-21. doi: 10.1128/AEM.00156-21. Online ahead of print.
 
Fungi and Fungal Metabolites for the Improvement of Human and Animal Nutrition and Health.
Dufossé L, Fouillaud M, Caro Y.
J Fungi (Basel). 2021 Apr 4;7(4):274. doi: 10.3390/jof7040274.
 
Structural characterization and amelioration of sulfated polysaccharides from Ganoderma applanatum residue against CCl(4)-induced hepatotoxicity.
Song X, Cui W, Gao Z, Zhang J, Jia L.
Int Immunopharmacol. 2021 Mar 31;96:107554. doi: 10.1016/j.intimp.2021.107554. Online ahead of print.
 
PLGA nanoparticles containing Lingzhi extracts rescue corneal epithelial cells from oxidative damage.
Tsai IL, Tsai CY, Kuo LL, Woung LC, Ku RY, Cheng YH.
Exp Eye Res. 2021 May;206:108539. doi: 10.1016/j.exer.2021.108539. Epub 2021 Mar 17.
 
Production, characterization, and bioactivities of exopolysaccharides from the submerged culture of Ganoderma cantharelloideum M. H. Liu.
Long Z, Xue Y, Ning Z, Sun J, Li J, Su Z, Liu Q, Xu C, Yan JK.
3 Biotech. 2021 Mar;11(3):145. doi: 10.1007/s13205-021-02696-w. Epub 2021 Feb 26.
 
Effect of the heme oxygenase gene on mycelial growth and polysaccharide synthesis in Ganoderma lucidum.
Wang T, Wang Y, Chen C, Ren A, Yu H, Zhao M.
J Basic Microbiol. 2021 Mar;61(3):253-264. doi: 10.1002/jobm.202000622. Epub 2021 Feb 5.
 
Characterization and Hepatoprotections of Ganoderma lucidum Polysaccharides against Multiple Organ Dysfunction Syndrome in Mice.
Zhang Y, Feng Y, Wang W, Jia L, Zhang J.
Oxid Med Cell Longev. 2021 Feb 3;2021:9703682. doi: 10.1155/2021/9703682. eCollection 2021.
 
Impact of olive mill wastewaters on the physiological behavior of a wild-type new Ganoderma resinaceum isolate.
Diamantopoulou P, Gardeli C, Papanikolaou S.
Environ Sci Pollut Res Int. 2021 Apr;28(16):20570-20585. doi: 10.1007/s11356-020-11835-4. Epub 2021 Jan 6.
 
Effects of redox interference on the pancreatic mitochondria and the abnormal blood glucose.
Xie F, Wu M, Lai B, Halim M, Liu S, Shi D.
Free Radic Res. 2021 Jan 4:1-12. doi: 10.1080/10715762.2020.1866180. Online ahead of print.
 
Biological Activities of Different Strains of the Genus Ganoderma spp. (Agaricomycetes) from Mexico.
Espinosa-García V, Mendoza G, Shnyreva AV, Padrón JM, Trigos Á.
Int J Med Mushrooms. 2021;23(2):67-77. doi: 10.1615/IntJMedMushrooms.2021037451.
 
Optimization of ultrasonic-assisted extraction of polysaccharides and triterpenoids from the medicinal mushroom Ganoderma lucidum and evaluation of their in vitro antioxidant capacities.
Zheng S, Zhang W, Liu S.
PLoS One. 2020 Dec 31;15(12):e0244749. doi: 10.1371/journal.pone.0244749. eCollection 2020.
 
Anti-Inflammatory, Antioxidant and Enzyme Inhibition Activities in Correlation with Mycochemical Profile of Selected Indigenous Ganoderma spp. from Balkan Region (Serbia).
Rašeta M, Popović M, Beara I, Šibul F, Zengin G, Krstić S, Karaman M.
Chem Biodivers. 2021 Feb;18(2):e2000828. doi: 10.1002/cbdv.202000828. Epub 2020 Dec 29.
 
Pleurotus Macrofungi-Assisted Nanoparticle Synthesis and Its Potential Applications: A Review.
Bhardwaj K, Sharma A, Tejwan N, Bhardwaj S, Bhardwaj P, Nepovimova E, Shami A, Kalia A, Kumar A, Abd-Elsalam KA, Kuča K.
J Fungi (Basel). 2020 Dec 9;6(4):351. doi: 10.3390/jof6040351.
 
Effect and Mechanism of Ganoderma lucidum Spores on Alleviation of Diabetic Cardiomyopathy in a Pilot in vivo Study.
Shaher F, Wang S, Qiu H, Hu Y, Zhang Y, Wang W, Al-Ward H, Abdulghani MAM, Baldi S, Zhou S.
Diabetes Metab Syndr Obes. 2020 Dec 7;13:4809-4822. doi: 10.2147/DMSO.S281527. eCollection 2020.
 
One-pot fabrication of sacchachitin for production of TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) utilized as scaffolds to enhance bone regeneration.
Wu MH, Wang W, Chao FC, Hsieh CM, Chen LC, Lin HL, Ho HO, Huang TJ, Sheu MT.
Carbohydr Polym. 2021 Feb 15;254:117270. doi: 10.1016/j.carbpol.2020.117270. Epub 2020 Nov 7.
 
The Novel Herbal Cocktail AGA Alleviates Oral Cancer through Inducing Apoptosis, Inhibited Migration and Promotion of Cell Cycle Arrest at SubG1 Phase.
Lu JH, Chou YR, Deng YH, Huang MS, Chien ST, Quynh BTN, Wu CY, Peláez Achtmann EA, Cheng HC, Dubey NK, Deng WP.
Cancers (Basel). 2020 Oct 31;12(11):3214. doi: 10.3390/cancers12113214.
 
Comparison of physicochemical and biochemical properties of natural and arginine-modified melanin from medicinal mushroom Ganoderma lucidum.
Xu L, Li J, Chang M, Cheng Y, Geng X, Meng J, Zhu M.
J Basic Microbiol. 2020 Nov;60(11-12):1014-1028. doi: 10.1002/jobm.202000430. Epub 2020 Oct 26.
 
Isolation, structural characterization, and biological activities of galactomannans from Rhizopogon luteolus and Ganoderma adspersum mushrooms.
Tel-Çayan G, Muhammad A, Deveci E, Duru ME, Öztürk M.
Int J Biol Macromol. 2020 Dec 15;165(Pt B):2395-2403. doi: 10.1016/j.ijbiomac.2020.10.040. Epub 2020 Oct 13.
 
Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials.
Grammatikopoulou MG, Gkiouras K, Papageorgiou SΤ, Myrogiannis I, Mykoniatis I, Papamitsou T, Bogdanos DP, Goulis DG.
Nutrients. 2020 Sep 29;12(10):2985. doi: 10.3390/nu12102985.
 
Natural compounds against doxorubicin-induced cardiotoxicity: A review on the involvement of Nrf2/ARE signaling pathway.
Yarmohammadi F, Rezaee R, Karimi G.
Phytother Res. 2021 Mar;35(3):1163-1175. doi: 10.1002/ptr.6882. Epub 2020 Sep 28.
 
Ganoderma Lucidum from Red Mushroom Attenuates Formaldehyde-Induced Liver Damage in Experimental Male Rat Model.
Oluwafemi Adetuyi B, Olamide Okeowo T, Adefunke Adetuyi O, Abraham Adebisi O, Ogunlana OO, Janet Oretade O, Marraiki N, Beshbishy AM, N Welson N, Batiha GE.
Biology (Basel). 2020 Sep 27;9(10):313. doi: 10.3390/biology9100313.
 
Ganoderma lucidum inspired silver nanoparticles and its biomedical applications with special reference to drug resistant Escherichia coli isolates from CAUTI.
Al-Ansari MM, Dhasarathan P, Ranjitsingh AJA, Al-Humaid LA.
Saudi J Biol Sci. 2020 Nov;27(11):2993-3002. doi: 10.1016/j.sjbs.2020.09.008. Epub 2020 Sep 10.
 
Protective effects of curcumin and Ganoderma lucidum on hippocampal damage caused by the organophosphate insecticide chlorpyrifos in the developing rat brain: Stereological, histopathological and immunohistochemical study.
Eronat K, Sağır D.
Acta Histochem. 2020 Oct;122(7):151621. doi: 10.1016/j.acthis.2020.151621. Epub 2020 Sep 9.
 
Ganoderma lucidum Ethanol Extracts Enhance Re-Epithelialization and Prevent Keratinocytes from Free-Radical Injury.
Abate M, Pepe G, Randino R, Pisanti S, Basilicata MG, Covelli V, Bifulco M, Cabri W, D'Ursi AM, Campiglia P, Rodriquez M.
Pharmaceuticals (Basel). 2020 Aug 29;13(9):224. doi: 10.3390/ph13090224.
 
In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cells.
Lau MF, Chua KH, Sabaratnam V, Kuppusamy UR.
Biotechnol Appl Biochem. 2020 Aug 28. doi: 10.1002/bab.2013. Online ahead of print.
 
Evaluation of the protective effects of Ganoderma applanatum against doxorubicin-induced toxicity in Dalton's Lymphoma Ascites (DLA) bearing mice.
Lalmuansangi C, Zosangzuali M, Lalremruati M, Tochhawng L, Siama Z.
Drug Chem Toxicol. 2020 Aug 28:1-11. doi: 10.1080/01480545.2020.1812630. Online ahead of print.
 
Effects of co-administration of Ganoderma terpenoid extract with chloroquine on inflammatory markers and antioxidant status in Plasmodium berghei-infected mice.
Oluba OM, Akpor OB, Adebiyi FD, Josiah SJ, Alabi OO, Shoyombo AO, Olusola AO.
J Integr Med. 2020 Nov;18(6):522-529. doi: 10.1016/j.joim.2020.08.002. Epub 2020 Aug 13.
 
Amelioration of the Lipogenesis, Oxidative Stress and Apoptosis of Hepatocytes by a Novel Proteoglycan from Ganoderma lucidum.
Yuan S, Pan Y, Zhang Z, He Y, Teng Y, Liang H, Wu X, Yang H, Zhou P.
Biol Pharm Bull. 2020 Oct 1;43(10):1542-1550. doi: 10.1248/bpb.b20-00358. Epub 2020 Aug 5.
 
Enhanced exopolysaccharide production in submerged fermentation of Ganoderma lucidum by Tween 80 supplementation.
Yang X, Yang Y, Zhang Y, He J, Xie Y.
Bioprocess Biosyst Eng. 2021 Jan;44(1):47-56. doi: 10.1007/s00449-020-02418-1. Epub 2020 Aug 2.
 
Ganoderma lucidum Ameliorates Neurobehavioral Changes and Oxidative Stress Induced by Ethanol Binge Drinking.
Nascimento CP, Luz DA, da Silva CCS, Malcher CMR, Fernandes LMP, Dalla Santa HS, Gomes ARQ, Monteiro MC, Ribeiro CHMA, Fontes-Júnior EA, Maia CSF.
Oxid Med Cell Longev. 2020 Jul 30;2020:2497845. doi: 10.1155/2020/2497845. eCollection 2020.
 
Associated Targets of the Antioxidant Cardioprotection of Ganoderma lucidum in Diabetic Cardiomyopathy by Using Open Targets Platform: A Systematic Review.
Shaher F, Qiu H, Wang S, Hu Y, Wang W, Zhang Y, Wei Y, Al-Ward H, Abdulghani MAM, Alenezi SK, Baldi S, Zhou S.
Biomed Res Int. 2020 Jul 25;2020:7136075. doi: 10.1155/2020/7136075. eCollection 2020.
 
Optimization of antioxidant, anti-diabetic, and anti-inflammatory activities and ganoderic acid content of differentially dried Ganoderma lucidum using response surface methodology.
Ryu DH, Cho JY, Sadiq NB, Kim JC, Lee B, Hamayun M, Lee TS, Kim HS, Park SH, Nho CW, Kim HY.
Food Chem. 2021 Jan 15;335:127645. doi: 10.1016/j.foodchem.2020.127645. Epub 2020 Jul 25.
 
Ganoderma lucidum Prevents Cisplatin-Induced Nephrotoxicity through Inhibition of Epidermal Growth Factor Receptor Signaling and Autophagy-Mediated Apoptosis.
Mahran YF, Hassan HM.
Oxid Med Cell Longev. 2020 Jul 6;2020:4932587. doi: 10.1155/2020/4932587. eCollection 2020.
 
Antioxidant, Cytotoxic and Antimicrobial Activity of Chitosan Preparations Extracted from Ganoderma Lucidum Mushroom.
Savin S, Craciunescu O, Oancea A, Ilie D, Ciucan T, Antohi LS, Toma A, Nicolescu A, Deleanu C, Oancea F.
Chem Biodivers. 2020 Jul;17(7):e2000175. doi: 10.1002/cbdv.202000175. Epub 2020 Jun 5.
 
Ganoderma lucidum: A rational pharmacological approach to surmount cancer.
Ahmad MF.
J Ethnopharmacol. 2020 Oct 5;260:113047. doi: 10.1016/j.jep.2020.113047. Epub 2020 Jun 3.
 
Extraction of triterpenoid compounds from Ganoderma Lucidum spore powder through a dual-mode sonication process.
Shen SF, Zhu LF, Wu Z, Wang G, Ahmad Z, Chang MW.
Drug Dev Ind Pharm. 2020 Jun;46(6):963-974. doi: 10.1080/03639045.2020.1764022. Epub 2020 May 13.
 
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety.
Shaito A, Thuan DTB, Phu HT, Nguyen THD, Hasan H, Halabi S, Abdelhady S, Nasrallah GK, Eid AH, Pintus G.
Front Pharmacol. 2020 Apr 7;11:422. doi: 10.3389/fphar.2020.00422. eCollection 2020.
 
Ganoderma lucidum Triterpenoids (GLTs) Reduce Neuronal Apoptosis via Inhibition of ROCK Signal Pathway in APP/PS1 Transgenic Alzheimer's Disease Mice.
Yu N, Huang Y, Jiang Y, Zou L, Liu X, Liu S, Chen F, Luo J, Zhu Y.
Oxid Med Cell Longev. 2020 Jan 28;2020:9894037. doi: 10.1155/2020/9894037. eCollection 2020.
 
Effect of Cultured Substrates on the Chemical Composition and Biological Activities of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).
Song T, Zhang Z, Liu S, Chen J, Cai W.
Int J Med Mushrooms. 2020;22(12):1183-1190. doi: 10.1615/IntJMedMushrooms.2020037133.
 
Comparative Study on Bioactivities from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Gives an Insight into the Fermentation Broth Showing Greater Antioxidative Activities.
Xie C, Tang P, Yan S, Yang Q, Zhang Z, Gong W, Zhu Z, Zhou Y, Yan L, Hu Z, Wang X, Peng Y.
Int J Med Mushrooms. 2020;22(7):627-639. doi: 10.1615/IntJMedMushrooms.2020035042.
 
Effects of Extraction Temperature on Efficacy of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Aqueous Extract against Oxidative Stress.
Tulsawani R, Sharma P, Manimaran M, Koganti P, Singh M, Meena DK, Negi PS, Misra K.
Int J Med Mushrooms. 2020;22(6):547-558. doi: 10.1615/IntJMedMushrooms.2020035074.
 
Bioactivities and Molecular Characterizations of the Polysaccharide(s) from Ultrasonic-Circulating Extracts of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).
Chen TQ, Kan YJ, Yang C, Wu JG, Wu JZ.
Int J Med Mushrooms. 2020;22(5):455-466. doi: 10.1615/IntJMedMushrooms.2020034227.
 
Effect of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Capsules on Colistin-Induced Nephrotoxicity.
Talih G, Kantekin ÇÜ, Göçmen Y, Çelik S, Talih T, Esmaoğlu A.
Int J Med Mushrooms. 2020;22(5):445-453. doi: 10.1615/IntJMedMushrooms.2020034229.
 
Antioxidant Activities of Selected Medicinal Mushroom Submerged Cultivated Mycelia.
Liu YM, Lai YH, Hsieh FM, Chiu YM, Wasser SP, Mau JL.
Int J Med Mushrooms. 2020;22(4):367-377. doi: 10.1615/IntJMedMushrooms.2020034161.
 
Comparative Studies on Bioactive Compounds, Ganoderic Acid Biosynthesis, and Antioxidant Activity of Pileus and Stipes of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) Fruiting Body at Different Growth Stages.
Ren X, Wang J, Huang L, Cheng K, Zhang M, Yang H.
Int J Med Mushrooms. 2020;22(2):133-144. doi: 10.1615/IntJMedMushrooms.2020033683.
 
Deacetyl Ganoderic Acid F Inhibits LPS-Induced Neural Inflammation via NF-κB Pathway Both In Vitro and In Vivo.
Sheng F, Zhang L, Wang S, Yang L, Li P.
Nutrients. 2019 Dec 27;12(1):85. doi: 10.3390/nu12010085.
 
Anti-aging Effect of Ganoderma (Lingzhi) with Health and Fitness.
Pan Y, Lin Z.
Adv Exp Med Biol. 2019;1182:299-309. doi: 10.1007/978-981-32-9421-9_13. Review.
 
Herbal Medicine for Slowing Aging and Aging-Associated Conditions: Efficacy, Mechanisms, and Safety.
Phu HT, Thuan DTB, Nguyen THD, Posadino AM, Eid AH, Pintus G.
Curr Vasc Pharmacol. 2019 Jul 15. doi: 10.2174/1570161117666190715121939. 
 
Alcohol Extracts From Ganoderma lucidum Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents.
Lai G, Guo Y, Chen D, Tang X, Shuai O, Yong T, Wang D, Xiao C, Zhou G, Xie Y, Yang BB, Wu Q.
Front Pharmacol. 2019 Mar 26;10:272. doi: 10.3389/fphar.2019.00272. eCollection 2019.
 
Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway.
Li HN, Zhao LL, Zhou DY, Chen DQ.
Med Sci Monit. 2020 Apr 4;26:e921905. doi: 10.12659/MSM.921905.
 
Rutin protects boar sperm from cryodamage via enhancing the antioxidative defense.
Xu D, Wu L, Yang L, Liu D, Chen H, Geng G, Li Q.
Anim Sci J. 2020 Jan;91(1):e13328. doi: 10.1111/asj.13328.
 
The protective effect of Ganoderma lucidum on testicular torsion/detorsion-induced ischemia-reperfusion (I/R) injury.
Doğan G, İpek H.
Acta Cir Bras. 2020 Mar 20;35(1):e202000103. doi: 10.1590/s0102-865020200010000003. eCollection 2020.
 
Effects of sporoderm-broken spores of Ganoderma lucidum on growth performance, antioxidant function and immune response of broilers.
Liu T, Zhou J, Li W, Rong X, Gao Y, Zhao L, Fan Y, Zhang J, Ji C, Ma Q.
Anim Nutr. 2020 Mar;6(1):39-46. doi: 10.1016/j.aninu.2019.11.005. Epub 2019 Dec 23.
 
Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review.
Lu J, He R, Sun P, Zhang F, Linhardt RJ, Zhang A.
Int J Biol Macromol. 2020 May 1;150:765-774. doi: 10.1016/j.ijbiomac.2020.02.035. Epub 2020 Feb 6. Review.
 
Functions of reactive oxygen species in apoptosis and ganoderic acid biosynthesis in Ganoderma lucidum.
Zhu J, Wu F, Yue S, Chen C, Song S, Wang H, Zhao M.
FEMS Microbiol Lett. 2019 Dec 1;366(23). pii: fnaa015. doi: 10.1093/femsle/fnaa015.
 
Ergosterol Peroxide from the Medicinal Mushroom Ganoderma lucidum Inhibits Differentiation and Lipid Accumulation of 3T3-L1 Adipocytes.
Jeong YU, Park YJ.
Int J Mol Sci. 2020 Jan 10;21(2). pii: E460. doi: 10.3390/ijms21020460.
 
Ganoderma carnosum and Ganoderma pfeifferi: Metal concentration, phenolic content, and biological activity.
Yalcin OU, Sarikurkcu C, Cengiz M, Gungor H, Ćavar Zeljković S.
Mycologia. 2020 Jan-Feb;112(1):1-8. doi: 10.1080/00275514.2019.1689748. Epub 2020 Jan 3.
 
The Effect of Mushroom Extracts on Human Platelet and Blood Coagulation: In vitro Screening of Eight Edible Species.
Poniedziałek B, Siwulski M, Wiater A, Komaniecka I, Komosa A, Gąsecka M, Magdziak Z, Mleczek M, Niedzielski P, Proch J, Ropacka-Lesiak M, Lesiak M, Henao E, Rzymski P.
Nutrients. 2019 Dec 12;11(12). pii: E3040. doi: 10.3390/nu11123040.
 
Triterpenes and Aromatic Meroterpenoids with Antioxidant Activity and Neuroprotective Effects from Ganoderma lucidum.
Wang C, Liu X, Lian C, Ke J, Liu J.
Molecules. 2019 Nov 28;24(23). pii: E4353. doi: 10.3390/molecules24234353.
 
Ganoderma lucidum, a promising agent possessing antioxidant and anti-inflammatory effects for treating calvarial defects with graft application in rats.
Laçin N, İzol SB, İpek F, Tuncer MC.
Acta Cir Bras. 2019 Nov 25;34(9):e201900904. doi: 10.1590/s0102-865020190090000004. eCollection 2019.
 
Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Skin Diseases and Care.
Yin Z, Yang B, Ren H.
Adv Exp Med Biol. 2019;1182:311-321. doi: 10.1007/978-981-32-9421-9_14. Review.
 
Antioxidative and Free Radical Scavenging Activity of Ganoderma (Lingzhi).
Lin Z, Deng A.
Adv Exp Med Biol. 2019;1182:271-297. doi: 10.1007/978-981-32-9421-9_12. Review.
 
Protective Effect of Ganoderma (Lingzhi) on Cardiovascular System.
Meng J, Yang B.
Adv Exp Med Biol. 2019;1182:181-199. doi: 10.1007/978-981-32-9421-9_7. Review.
 
Evidence for Effective Inhibitory Actions on Hyperpolarization-Activated Cation Current Caused by Ganoderma Triterpenoids, the Main Active Constitutents of Ganoderma Spores.
Chang WT, Gao ZH, Lo YC, Wu SN.
Molecules. 2019 Nov 22;24(23). pii: E4256. doi: 10.3390/molecules24234256.
 
Production of triterpenoid compounds from Ganoderma lucidum spore powder using ultrasound-assisted extraction.
Shen SF, Zhu LF, Wu Z, Wang G, Ahmad Z, Chang MW.
Prep Biochem Biotechnol. 2020;50(3):302-315. doi: 10.1080/10826068.2019.1692218. Epub 2019 Nov 22.
 
Synthesis and characterization of Reishi mushroom-mediated green synthesis of silver nanoparticles for the biochemical applications.
Aygün A, Özdemir S, Gülcan M, Cellat K, Şen F.
J Pharm Biomed Anal. 2020 Jan 30;178:112970. doi: 10.1016/j.jpba.2019.112970. Epub 2019 Nov 4.
 
Biovalorization of soybean residue (okara) via fermentation with Ganoderma lucidum and Lentinus edodes to attain products with high anti-osteoporotic effects.
Yang LC, Fu TJ, Yang FC.
J Biosci Bioeng. 2020 Apr;129(4):514-518. doi: 10.1016/j.jbiosc.2019.10.003. Epub 2019 Nov 7.
 
High Oxygen Treatments Enhance the Contents of Phenolic Compound and Ganoderic Acid, and the Antioxidant and DNA Damage Protective Activities of Ganoderma lingzhi Fruiting Body.
Dong Q, Li Y, Liu G, Zhang Z, Zhou H, Yang H.
Front Microbiol. 2019 Oct 18;10:2363. doi: 10.3389/fmicb.2019.02363. eCollection 2019.
 
Bioactivity-Guided Isolation of Acetylcholinesterase Inhibitor from Ganoderma mediosinense (Agaricomycetes).
Kaur A, Randhawa K, Singh V, Shri R.
Int J Med Mushrooms. 2019;21(8):755-763. doi: 10.1615/IntJMedMushrooms.2019031508.
 
Ganoderma proteins and their potential applications in cosmetics.
Li LD, Mao PW, Shao KD, Bai XH, Zhou XW.
Appl Microbiol Biotechnol. 2019 Dec;103(23-24):9239-9250. doi: 10.1007/s00253-019-10171-z. Epub 2019 Oct 29. 
 
Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma with Ganoderma lucidum Extracts.
Huh S, Lee S, Choi SJ, Wu Z, Cho JH, Kim L, Shin YS, Kang BW, Kim JG, Liu K, Cho H, Kang H.
Molecules. 2019 Oct 24;24(21). pii: E3834. doi: 10.3390/molecules24213834.
 
Oregonensins A and B, new meroterpenoids from the culture broth of Ganoderma oregonense and their antioxidant activity.
Kim JY, Woo EE, Ha LS, Kim YH, Lee IK, Yun BS.
J Antibiot (Tokyo). 2020 Feb;73(2):112-115. doi: 10.1038/s41429-019-0248-y. Epub 2019 Oct 15.
 
Pharmacological effects of Ganoderma lucidum extract against high-altitude stressors and its subchronic toxicity assessment.
Sharma P, Tulsawani R, Agrawal U.
J Food Biochem. 2019 Dec;43(12):e13081. doi: 10.1111/jfbc.13081. Epub 2019 Oct 14.
 
Antigenotoxic and antioxidant potential of medicinal mushrooms (Immune Assist) against DNA damage induced by free radicals-an in vitro study.
Živković L, Bajić V, Bruić M, Borozan S, Popić K, Topalović D, Santibanez J, Spremo-Potparević B.
Mutat Res. 2019 Sep;845:403078. doi: 10.1016/j.mrgentox.2019.06.008. Epub 2019 Aug 1.
 
C28 steroids from the fruiting bodies of Ganoderma resinaceum with potential anti-inflammatory activity.
Shi Q, Huang Y, Su H, Gao Y, Peng X, Zhou L, Li X, Qiu M.
Phytochemistry. 2019 Dec;168:112109. doi: 10.1016/j.phytochem.2019.112109. Epub 2019 Sep 5.
 
Structural characterization and determination of biological activities for different polysaccharides extracted from tree mushroom species.
Deveci E, Çayan F, Tel-Çayan G, Duru ME.
J Food Biochem. 2019 Sep;43(9):e12965. doi: 10.1111/jfbc.12965. Epub 2019 Jul 2.
 
Evaluation of the protective effects of Ganoderma atrum polysaccharide on acrylamide-induced injury in small intestine tissue of rats.
Yang Y, Zhang L, Jiang G, Lei A, Yu Q, Xie J, Chen Y.
Food Funct. 2019 Sep 1;10(9):5863-5872. doi: 10.1039/c9fo01452g. Epub 2019 Aug 29.
 
GSP-2, a polysaccharide extracted from Ganoderma sinense, is a novel toll-like receptor 4 agonist.
Liu KS, Zhang C, Dong HL, Li KK, Han QB, Wan Y, Chen R, Yang F, Li HL, Ko CH, Han XQ.
PLoS One. 2019 Aug 23;14(8):e0221636. doi: 10.1371/journal.pone.0221636. eCollection 2019.
 
Use of Ganoderma Lucidum polysaccharide to control cotton fusarium wilt, and the mechanism involved.
Zhang Z, Diao H, Wang H, Wang K, Zhao M.
Pestic Biochem Physiol. 2019 Jul;158:149-155. doi: 10.1016/j.pestbp.2019.05.003. Epub 2019 May 11.
 
Facile Nanolization Strategy for Therapeutic Ganoderma Lucidum Spore Oil to Achieve Enhanced Protection against Radiation-Induced Heart Disease.
Dai C, He L, Ma B, Chen T.
Small. 2019 Sep;15(36):e1902642. doi: 10.1002/smll.201902642. Epub 2019 Jul 28.
 
The ameliorations of Ganoderma applanatum residue polysaccharides against CCl4 induced liver injury.
Gao Z, Yuan F, Li H, Feng Y, Zhang Y, Zhang C, Zhang J, Song Z, Jia L.
Int J Biol Macromol. 2019 Sep 15;137:1130-1140. doi: 10.1016/j.ijbiomac.2019.07.044. Epub 2019 Jul 8.
 
GPP (Composition of Ganoderma Lucidum Poly-saccharides and Polyporus Umbellatus Poly-saccharides) Enhances Innate Immune Function in Mice.
Huang Q, Li L, Chen H, Liu Q, Wang Z.
Nutrients. 2019 Jun 28;11(7). pii: E1480. doi: 10.3390/nu11071480.
 
Evaluation of laccase production by Ganoderma lucidum in submerged and solid-state fermentation using different inducers.
Rodrigues EM, Karp SG, Malucelli LC, Helm CV, Alvarez TM.
J Basic Microbiol. 2019 Aug;59(8):784-791. doi: 10.1002/jobm.201900084. Epub 2019 Jul 1.
 
Effects of Macuprev® Supplementation in Age-Related Macular Degeneration: A Double-Blind Randomized Morpho-Functional Study Along 6 Months of Follow-Up.
Parravano M, Tedeschi M, Manca D, Costanzo E, Di Renzo A, Giorno P, Barbano L, Ziccardi L, Varano M, Parisi V.
Adv Ther. 2019 Sep;36(9):2493-2505. doi: 10.1007/s12325-019-01016-2. Epub 2019 Jun 25. Erratum in: Adv Ther. 2019 Nov;36(11):3288. 
 
Protective effects of Ganoderma lucidum triterpenoids on oxidative stress and apoptosis in the spleen of chickens induced by cadmium.
Teng X, Zhang W, Song Y, Wang H, Ge M, Zhang R.
Environ Sci Pollut Res Int. 2019 Aug;26(23):23967-23980. doi: 10.1007/s11356-019-05638-5. Epub 2019 Jun 20.
 
Interdependent nitric oxide and hydrogen peroxide independently regulate the coix seed oil-induced triterpene acid accumulation in Ganoderma lingzhi.
Liu YN, Tong T, Zhang RR, Liu LM, Shi ML, Ma YC, Liu GQ.
Mycologia. 2019 Jul-Aug;111(4):529-540. doi: 10.1080/00275514.2019.1615816. Epub 2019 Jun 3.
 
Characterization, hypolipidemic and antioxidant activities of degraded polysaccharides from Ganoderma lucidum.
Xu Y, Zhang X, Yan XH, Zhang JL, Wang LY, Xue H, Jiang GC, Ma XT, Liu XJ.
Int J Biol Macromol. 2019 Aug 15;135:706-716. doi: 10.1016/j.ijbiomac.2019.05.166. Epub 2019 May 23.
 
Anti-inflammatory, anti-nociceptive and sedative-hypnotic activities of lucidone D extracted from Ganoderma lucidum.
Feng X, Wang Y.
Cell Mol Biol (Noisy-le-grand). 2019 Apr 30;65(4):37-42.
 
Ganoderma lucidum polysaccharide used for treating physical frailty in China.
Zeng P, Chen Y, Zhang L, Xing M.
Prog Mol Biol Transl Sci. 2019;163:179-219. doi: 10.1016/bs.pmbts.2019.02.009. Epub 2019 Mar 26. Review.
 
Ganoderma sinense polysaccharide: An adjunctive drug used for cancer treatment.
Zhang Y, Jiang Y, Zhang M, Zhang L.
Prog Mol Biol Transl Sci. 2019;163:165-177. doi: 10.1016/bs.pmbts.2019.02.008. Epub 2019 Mar 25. Review.
 
Kinetic identification of phenolic compounds and potential production of caffeic acid by Ganoderma lipsiense in solid-state fermentation.
Costa TM, Kaufmann V, Paganelli CJ, Siebert DA, Micke GA, Alberton MD, Tavares LBB, de Oliveira D.
Bioprocess Biosyst Eng. 2019 Aug;42(8):1325-1332. doi: 10.1007/s00449-019-02131-8. Epub 2019 Apr 26.
 
Optimization of Cultivation Conditions of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) for the Highest Antioxidant Activity and Antioxidant Content.
Lou HW, Guo XY, Zhang XC, Guo LQ, Lin JF.
Int J Med Mushrooms. 2019;21(4):353-366. doi: 10.1615/IntJMedMushrooms.2019030338.
 
[Study on chemical constituents from fruiting bodies of Ganoderma australe].
Ge YZ, Ma QY, Kong FD, Xie QY, An CL, Yu ZF, Zhao YX.
Zhongguo Zhong Yao Za Zhi. 2019 Feb;44(3):489-494. doi: 10.19540/j.cnki.cjcmm.20181121.004. Chinese.
 
Effect of the taxonomic group of fungi and type of substrate on the antioxidant activity of a solid-state fermentation system.
El-Katony TM, El-Dein MMN, El-Fallal AA, Ibrahim NG.
Int Microbiol. 2019 Jun;22(2):203-215. doi: 10.1007/s10123-018-00040-6. Epub 2018 Nov 9.
 
Aromatic constituents from Ganoderma lucidum and their neuroprotective and anti-inflammatory activities.
Lu SY, Peng XR, Dong JR, Yan H, Kong QH, Shi QQ, Li DS, Zhou L, Li ZR, Qiu MH.
Fitoterapia. 2019 Apr;134:58-64. doi: 10.1016/j.fitote.2019.01.013. Epub 2019 Feb 11.
 
De novo transcriptome assembly and protein profiling of copper-induced lignocellulolytic fungus Ganoderma lucidum MDU-7 reveals genes involved in lignocellulose degradation and terpenoid biosynthetic pathways.
Jain KK, Kumar A, Shankar A, Pandey D, Chaudhary B, Sharma KK.
Genomics. 2020 Jan;112(1):184-198. doi: 10.1016/j.ygeno.2019.01.012. Epub 2019 Jan 26.
 
Effects of Fungal Polysaccharide on Oxidative Damage and TLR4 Pathway to the Central Immune Organs in Cadmium Intoxication in Chickens.
Li R, Zhang L, Tang Z, Li T, Li G, Zhang R, Ge M.
Biol Trace Elem Res. 2019 Oct;191(2):464-473. doi: 10.1007/s12011-018-1627-0. Epub 2019 Jan 10.
 
Antioxidant potential of ganoderic acid in Notch-1 protein in neuroblastoma.
Gill BS, Navgeet, Kumar S.
Mol Cell Biochem. 2019 Jun;456(1-2):1-14. doi: 10.1007/s11010-018-3485-7. Epub 2018 Dec 3.
 
Comparison on characterization and antioxidant activity of polysaccharides from Ganoderma lucidum by ultrasound and conventional extraction.
Kang Q, Chen S, Li S, Wang B, Liu X, Hao L, Lu J.
Int J Biol Macromol. 2019 Mar 1;124:1137-1144. doi: 10.1016/j.ijbiomac.2018.11.215. Epub 2018 Nov 24.
 
The anti-oxidation and anti-aging effects of Ganoderma lucidum in Caenorhabditis elegans.
Cuong VT, Chen W, Shi J, Zhang M, Yang H, Wang N, Yang S, Li J, Yang P, Fei J.
Exp Gerontol. 2019 Mar;117:99-105. doi: 10.1016/j.exger.2018.11.016. Epub 2018 Nov 23.
 
Ganoderma lucidum Ameliorates Non-Alcoholic Steatosis by Upregulating Energy Metabolizing Enzymes in the Liver.
Jung S, Son H, Hwang CE, Cho KM, Park SW, Kim HJ.
J Clin Med. 2018 Jun 15;7(6). pii: E152. doi: 10.3390/jcm7060152.
 
Effect of the taxonomic group of fungi and type of substrate on the antioxidant activity of a solid-state fermentation system.
El-Katony TM, El-Dein MMN, El-Fallal AA, Ibrahim NG.
Int Microbiol. 2018 Nov 9. doi: 10.1007/s10123-018-00040-6. 
 
Evaluation of the Antioxidative and Hypo-cholesterolemic Effects of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Ameliorating Cardiovascular Disease.
Rahman MA, Abdullah N, Aminudin N.
Int J Med Mushrooms. 2018;20(10):961-969. doi: 10.1615/IntJMedMushrooms.2018028370.
 
Bioprospecting of Wild Mushrooms from India with Respect to Their Medicinal Aspects.
Khan F, Chandra R.
Int J Med Mushrooms. 2019;21(2):181-192. doi: 10.1615/IntJMedMushrooms.2019029969.
 
Effects of Concurrently Administered Aqueous Extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), and Lead Acetate in Rats.
Sobowale MT, Ozolua RI, Uwaya DO, Ayinde BA.
Int J Med Mushrooms. 2019;21(2):143-154. doi: 10.1615/IntJMedMushrooms.2019029766.
 
Protective effects of Ganoderma triterpenoids on cadmium-induced oxidative stress and inflammatory injury in chicken livers.
Li T, Yu H, Song Y, Zhang R, Ge M.
J Trace Elem Med Biol. 2019 Mar;52:118-125. doi: 10.1016/j.jtemb.2018.12.010. Epub 2018 Dec 15.
 
Porous Yolk-Shell Particle Engineering via Nonsolvent-Assisted Trineedle Coaxial Electrospraying for Burn-Related Wound Healing.
Zhang C, Li Y, Hu Y, Peng Y, Ahmad Z, Li JS, Chang MW.
ACS Appl Mater Interfaces. 2019 Feb 27;11(8):7823-7835. doi: 10.1021/acsami.8b22112. Epub 2019 Feb 19.
 
De novo transcriptome assembly and protein profiling of copper-induced lignocellulolytic fungus Ganoderma lucidum MDU-7 reveals genes involved in lignocellulose degradation and terpenoid biosynthetic pathways.
Jain KK, Kumar A, Shankar A, Pandey D, Chaudhary B, Sharma KK.
Genomics. 2019 Jan 26. pii: S0888-7543(18)30526-3. doi: 10.1016/j.ygeno.2019.01.012.
 
Antioxidant and Anti-Inflammatory Activity and Cytotoxicity of Ethanol Extracts from Rhynchosia nulubilis Cultivated with Ganoderma lucidum Mycelium.
Park MH, Kim M.
Prev Nutr Food Sci. 2018 Dec;23(4):326-334. doi: 10.3746/pnf.2018.23.4.326. Epub 2018 Dec 31.
 
Phenolic Rich Fractions from Mycelium and Fruiting Body of Ganoderma lucidum Inhibit Bacterial Pathogens Mediated by Generation of Reactive Oxygen Species and Protein Leakage and Modulate Hypoxic Stress in HEK 293 Cell Line.
Mishra J, Joshi A, Rajput R, Singh K, Bansal A, Misra K.
Adv Pharmacol Sci. 2018 Dec 17;2018:6285615. doi: 10.1155/2018/6285615. eCollection 2018.
 
Effects of Fungal Polysaccharide on Oxidative Damage and TLR4 Pathway to the Central Immune Organs in Cadmium Intoxication in Chickens.
Li R, Zhang L, Tang Z, Li T, Li G, Zhang R, Ge M.
Biol Trace Elem Res. 2019 Jan 10. doi: 10.1007/s12011-018-1627-0. 
 
Effects of deproteinization methods on primary structure and antioxidant activity of Ganoderma lucidum polysaccharides.
Zeng X, Li P, Chen X, Kang Y, Xie Y, Li X, Xie T, Zhang Y.
Int J Biol Macromol. 2019 Apr 1;126:867-876. doi: 10.1016/j.ijbiomac.2018.12.222. Epub 2018 Dec 24.
 
Medium composition optimization, structural characterization, and antioxidant activity of exopolysaccharides from the medicinal mushroom Ganoderma lingzhi.
Si J, Meng G, Wu Y, Ma HF, Cui BK, Dai YC.
Int J Biol Macromol. 2019 Mar 1;124:1186-1196. doi: 10.1016/j.ijbiomac.2018.11.274. Epub 2018 Dec 3.
 
Phytochemical composition, antioxidant and antiproliferative activities and effects on nuclear DNA of ethanolic extract from an Italian mycelial isolate of Ganoderma lucidum.
Saltarelli R, Palma F, Gioacchini AM, Calcabrini C, Mancini U, De Bellis R, Stocchi V, Potenza L.
J Ethnopharmacol. 2019 Mar 1;231:464-473. doi: 10.1016/j.jep.2018.11.041. Epub 2018 Dec 1.
 
Antioxidant potential of ganoderic acid in Notch-1 protein in neuroblastoma.
Gill BS, Navgeet, Kumar S.
Mol Cell Biochem. 2018 Dec 3. doi: 10.1007/s11010-018-3485-7. 
 
Comparison on characterization and antioxidant activity of polysaccharides from Ganoderma lucidum by ultrasound and conventional extraction.
Kang Q, Chen S, Li S, Wang B, Liu X, Hao L, Lu J.
Int J Biol Macromol. 2019 Mar 1;124:1137-1144. doi: 10.1016/j.ijbiomac.2018.11.215. Epub 2018 Nov 24.
 
Ganoderma tsugae induced ROS-independent apoptosis and cytoprotective autophagy in human chronic myeloid leukemia cells.
Hseu YC, Shen YC, Kao MC, Mathew DC, Karuppaiya P, Li ML, Yang HL.
Food Chem Toxicol. 2019 Feb;124:30-44. doi: 10.1016/j.fct.2018.11.043. Epub 2018 Nov 19.
 
The role of polysaccharide peptide of Ganoderma lucidum as a potent antioxidant against atherosclerosis in high risk and stable angina patients.
Sargowo D, Ovianti N, Susilowati E, Ubaidillah N, Widya Nugraha A, Vitriyaturrida, Siwi Proboretno K, Failasufi M, Ramadhan F, Wulandari H, Waranugraha Y, Hayuning Putri D.
Indian Heart J. 2018 Sep - Oct;70(5):608-614. doi: 10.1016/j.ihj.2017.12.007. Epub 2017 Dec 14.
 
Ganoderma lucidum polysaccharide inhibits UVB-induced melanogenesis by antagonizing cAMP/PKA and ROS/MAPK signaling pathways.
Hu S, Huang J, Pei S, Ouyang Y, Ding Y, Jiang L, Lu J, Kang L, Huang L, Xiang H, Xiao R, Zeng Q, Chen J.
J Cell Physiol. 2019 May;234(5):7330-7340. doi: 10.1002/jcp.27492. Epub 2018 Oct 26.
 
Meroterpenoids from Ganoderma sinense protect hepatocytes and cardiomyocytes from oxidative stress induced injuries.
Gao S, Zhang P, Zhang C, Bao F, Li H, Chen L.
Fitoterapia. 2018 Nov;131:73-79. doi: 10.1016/j.fitote.2018.10.009. Epub 2018 Oct 9.
 
Hyperproduction of exopolysaccharides by submerged mycelial culture of Ganoderma lucidum using a solid seed grown in fine-powder of wheat bran and in vitro evaluation of the antioxidant activity of the exopolysaccharides produced.
Liu SR, Zhang WR.
Food Sci Biotechnol. 2018 Feb 28;27(4):1129-1136. doi: 10.1007/s10068-018-0343-z. eCollection 2018 Aug. Erratum in: Food Sci Biotechnol. 2018 Jun 12;27(4):1245. 
 
Targeting oxidative stress using tri-needle electrospray engineered Ganoderma lucidum polysaccharide-loaded porous yolk-shell particles.
Xing Z, Zhang C, Zhao C, Ahmad Z, Li JS, Chang MW.
Eur J Pharm Sci. 2018 Dec 1;125:64-73. doi: 10.1016/j.ejps.2018.09.016. Epub 2018 Sep 21.
 
Lanostane triterpenoids from Ganoderma luteomarginatum and their cytotoxicity against four human cancer cell lines.
Su HG, Zhou QM, Guo L, Huang YJ, Peng C, Xiong L.
Phytochemistry. 2018 Dec;156:89-95. doi: 10.1016/j.phytochem.2018.09.003. Epub 2018 Sep 18.
 
Hepatoprotective activity of Ganoderma lucidum triterpenoids in alcohol-induced liver injury in mice, an iTRAQ-based proteomic analysis.
Zhao C, Fan J, Liu Y, Guo W, Cao H, Xiao J, Wang Y, Liu B.
Food Chem. 2019 Jan 15;271:148-156. doi: 10.1016/j.foodchem.2018.07.115. Epub 2018 Jul 18.
 
Hypolipidemic, Antioxidant, and Antiapoptotic Effects of Polysaccharides Extracted from Reishi Mushroom, Ganoderma lucidum (Leysser: Fr) Karst, in Mice Fed a High-Fat Diet.
Liang Z, Yuan Z, Li G, Fu F, Shan Y.
J Med Food. 2018 Dec;21(12):1218-1227. doi: 10.1089/jmf.2018.4182. Epub 2018 Sep 5.
 
Ganoderma lucidum: Persuasive biologically active constituents and their health endorsement.
Ahmad MF.
Biomed Pharmacother. 2018 Nov;107:507-519. doi: 10.1016/j.biopha.2018.08.036. Epub 2018 Aug 13. Review.
 
Phenolics, tocopherols and fatty acid profiling of wild and commercial mushrooms from Pakistan.
Sharif S, Rashid S, Atta A, Irshad A, Riaz M, Shahid M, Mustafa G.
J Biol Regul Homeost Agents. 2018 Jul-Aug;32(4):863-867.
 
Total Syntheses and Biological Evaluation of the Ganoderma lucidum Alkaloids Lucidimines B and C.
Chen Y, Lan P.
ACS Omega. 2018 Mar 31;3(3):3471-3481. doi: 10.1021/acsomega.8b00295. Epub 2018 Mar 26.
 
Hypolipidaemic and anti-lipidperoxidant activities of Ganoderma lucidum polysaccharide.
Wu S.
Int J Biol Macromol. 2018 Oct 15;118(Pt B):2001-2005. doi: 10.1016/j.ijbiomac.2018.07.082. Epub 2018 Jul 22.
 
Role of Mushroom as Dietary Supplement on Performance of Poultry.
Khan SH, Mukhtar N, Iqbal J.
J Diet Suppl. 2018 Jul 3:1-14. doi: 10.1080/19390211.2018.1472707.
 
Antioxidant and Hepatoprotective Activities of Crude Polysaccharide Extracts from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), by Ultrasonic-Circulating Extraction.
Chen TQ, Wu JG, Kan YJ, Yang C, Wu YB, Wu JZ.
Int J Med Mushrooms. 2018;20(6):581-593. doi: 10.1615/IntJMedMushrooms.2018026536.
 
Antioxidant Properties of the Artist's Conk Medicinal Mushroom, Ganoderma applanatum (Agaricomycetes), upon Cultivation with para-Substituted Phenolic Compounds and Tea Leaf Extracts.
Tsivileva O, Pankratov A, Misin V, Zavyalov A, Volkov V, Tsymbal O, Yurasov N, Nikitina VE.
Int J Med Mushrooms. 2018;20(6):549-560. doi: 10.1615/IntJMedMushrooms.2018026329.
 
Incorporation of tocopherol-rich extracts from mushroom mycelia into yogurt.
Bouzgarrou C, Amara K, Reis FS, Barreira JCM, Skhiri F, Chatti N, Martins A, Barros L, Ferreira ICFR.
Food Funct. 2018 Jun 20;9(6):3166-3172. doi: 10.1039/c8fo00482j.
 
Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats.
Hossen MS, Billah Prince MM, Tanvir EM, Chowdhury MAZ, Rahman MA, Alam F, Paul S, Saha M, Ali MY, Bhoumik NC, Karim N, Gan SH, Khalil MI.
Evid Based Complement Alternat Med. 2018 May 15;2018:6254929. doi: 10.1155/2018/6254929. eCollection 2018.
 
Ganoderma Triterpenoids Exert Antiatherogenic Effects in Mice by Alleviating Disturbed Flow-Induced Oxidative Stress and Inflammation.
Hsu PL, Lin YC, Ni H, Mo FE.
Oxid Med Cell Longev. 2018 Apr 11;2018:3491703. doi: 10.1155/2018/3491703. eCollection 2018.
 
Evaluation of diuron tolerance and biotransformation by the white-rot fungus Ganoderma lucidum.
Coelho-Moreira JDS, Brugnari T, Sá-Nakanishi AB, Castoldi R, de Souza CGM, Bracht A, Peralta RM.
Fungal Biol. 2018 Jun;122(6):471-478. doi: 10.1016/j.funbio.2017.10.008. Epub 2017 Nov 2.
 
Effect of Selenium-containing Biocomposites from Medicinal Mushrooms on the Potato Ring Rot Causative Agent.
Perfileva AI, Tsivileva OM, Drevko YB, Ibragimova DN, Koftin OV.
Dokl Biol Sci. 2018 Mar;479(1):67-69. doi: 10.1134/S0012496618020072. Epub 2018 May 22.
 
Two new farnesyl phenolic compounds with anti-inflammatory activities from Ganoderma duripora.
Liu JQ, Lian CL, Hu TY, Wang CF, Xu Y, Xiao L, Liu ZQ, Qiu SQ, Cheng BH.
Food Chem. 2018 Oct 15;263:155-162. doi: 10.1016/j.foodchem.2018.04.097. Epub 2018 Apr 25.
 
Cell Proliferation and DNA Repair Ability of Ganoderma neo-japonicum (Agaricomycetes): An Indigenous Medicinal Mushroom from Malaysia.
Tan WC, Kuppusamy UR, Phan CW, Sabaratnam V.
Int J Med Mushrooms. 2018;20(2):155-163. doi: 10.1615/IntJMedMushrooms.2018025445.
 
Antimelanogenesis and Anti-Inflammatory Activity of Selected Culinary-Medicinal Mushrooms.
Saad HM, Sim KS, Tan YS.
Int J Med Mushrooms. 2018;20(2):141-153. doi: 10.1615/IntJMedMushrooms.2018025463.
 
Combinatorial usage of fungal polysaccharides from Cordyceps sinensis and Ganoderma atrum ameliorate drug-induced liver injury in mice.
Fan S, Huang X, Wang S, Li C, Zhang Z, Xie M, Nie S.
Food Chem Toxicol. 2018 Sep;119:66-72. doi: 10.1016/j.fct.2018.05.027. Epub 2018 May 16.
 
In vitro evaluation of the synergistic antioxidant and anti-inflammatory activities of the combined extracts from Malaysian Ganoderma lucidum and Egyptian Chlorella vulgaris.
Abu-Serie MM, Habashy NH, Attia WE.
BMC Complement Altern Med. 2018 May 10;18(1):154. doi: 10.1186/s12906-018-2218-5.
 
Hypouricemic Effect of 2,5-Dihydroxyacetophenone, a Computational Screened Bioactive Compound from Ganoderma applanatum, on Hyperuricemic Mice.
Liang D, Yong T, Chen S, Xie Y, Chen D, Zhou X, Li D, Li M, Su L, Zuo D.
Int J Mol Sci. 2018 May 7;19(5). pii: E1394. doi: 10.3390/ijms19051394.
 
Antioxidant Enzyme Activities and Secondary Metabolite Profiling of Oil Palm Seedlings Treated with Combination of NPK Fertilizers Infected with Ganoderma boninense.
Sahebi M, Hanafi MM, Mohidin H, Rafii MY, Azizi P, Idris AS, Fariz A, Abiri R, Taheri S, Moradpoor M.
Biomed Res Int. 2018 Mar 12;2018:1494157. doi: 10.1155/2018/1494157. eCollection 2018.
 
Novel Kombucha Beverage from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum, with Antibacterial and Antioxidant Effects.
Sknepnek A, Pantić M, Matijašević D, Miletić D, Lević S, Nedović V, Niksic M.
Int J Med Mushrooms. 2018;20(3):243-258. doi: 10.1615/IntJMedMushrooms.2018025833.
 
Protective Effect of Ganoderma Triterpenoids on Cadmium-Induced Testicular Toxicity in Chickens.
Wang H, Zhang R, Song Y, Li T, Ge M.
Biol Trace Elem Res. 2019 Jan;187(1):281-290. doi: 10.1007/s12011-018-1364-4. Epub 2018 May 2.
 
Structural Elucidation and Biomimetic Synthesis of (±)-Cochlactone A with Anti-Inflammatory Activity.
Peng XR, Lu SY, Shao LD, Zhou L, Qiu MH.
J Org Chem. 2018 May 18;83(10):5516-5522. doi: 10.1021/acs.joc.8b00525. Epub 2018 May 4.
 
Chemical, biochemical, preclinical and clinical studies of Ganoderma lucidum polysaccharide as an approved drug for treating myopathy and other diseases in China.
Zeng P, Guo Z, Zeng X, Hao C, Zhang Y, Zhang M, Liu Y, Li H, Li J, Zhang L.
J Cell Mol Med. 2018 Jul;22(7):3278-3297. doi: 10.1111/jcmm.13613. Epub 2018 Apr 24. Review.
 
Development of antler-type fruiting bodies of Ganoderma lucidum and determination of its biochemical properties.
Sudheer S, Taha Z, Manickam S, Ali A, Cheng PG.
Fungal Biol. 2018 May;122(5):293-301. doi: 10.1016/j.funbio.2018.01.007. Epub 2018 Feb 8.
 
Ganoderma lucidum Polysaccharide Peptide Attenuates Skin Flap Ischemia-Reperfusion Injury in a Thioredoxin-Dependent Manner.
Ren H, Meng X, Yin J, Sun J, Huang Q, Yin Z.
Plast Reconstr Surg. 2018 Jul;142(1):23e-33e. doi: 10.1097/PRS.0000000000004503.
 
Preparation of Bioactive Polysaccharide Nanoparticles with Enhanced Radical Scavenging Activity and Antimicrobial Activity.
Qin Y, Xiong L, Li M, Liu J, Wu H, Qiu H, Mu H, Xu X, Sun Q.
J Agric Food Chem. 2018 May 2;66(17):4373-4383. doi: 10.1021/acs.jafc.8b00388. Epub 2018 Apr 18.
 
Heat stress-induced reactive oxygen species participate in the regulation of HSP expression, hyphal branching and ganoderic acid biosynthesis in Ganoderma lucidum.
Liu R, Zhang X, Ren A, Shi DK, Shi L, Zhu J, Yu HS, Zhao MW.
Microbiol Res. 2018 Apr;209:43-54. doi: 10.1016/j.micres.2018.02.006. Epub 2018 Feb 19.
 
Racemic meroterpenoids from Ganoderma cochlear.
Peng X, Wang X, Chen L, Yang H, Li L, Lu S, Zhou L, Qiu M.
Fitoterapia. 2018 Jun;127:286-292. doi: 10.1016/j.fitote.2018.03.005. Epub 2018 Mar 11.
 
Effect of Ganoderma lucidum Powder on Oxidative Stability, Microbial and Sensory Properties of Emulsion Type Sausage.
Ghobadi R, Mohammadi R, Chabavizade J, Sami M.
Adv Biomed Res. 2018 Feb 16;7:24. doi: 10.4103/2277-9175.225595. eCollection 2018.
 
Emerging Roles of <i>Ganoderma Lucidum</i> in Anti-Aging.
Wang J, Cao B, Zhao H, Feng J.
Aging Dis. 2017 Dec 1;8(6):691-707. doi: 10.14336/AD.2017.0410. eCollection 2017 Dec. Review.
 
Effects of Ganoderma Lucidum shell-broken spore on oxidative stress of the rabbit urinary bladder using an in vivo model of ischemia/reperfusion.
Levin RM, Xia L, Wei W, Schuler C, Leggett RE, Lin AD.
Mol Cell Biochem. 2017 Nov;435(1-2):25-35. doi: 10.1007/s11010-017-3053-6. Epub 2017 May 8.
 
Determination of the Biological Efficiency and Antioxidant Potential of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Cultivated Using Different Agro-Wastes in Malaysia.
Sudheer S, Alzorqi I, Ali A, Cheng PG, Siddiqui Y, Manickam S.
Int J Med Mushrooms. 2018;20(1):89-100. doi: 10.1615/IntJMedMushrooms.2017024588.
 
Silver Nanoparticles Synthesized Using Wild Mushroom Show Potential Antimicrobial Activities against Food Borne Pathogens.
Mohanta YK, Nayak D, Biswas K, Singdevsachan SK, Abd Allah EF, Hashem A, Alqarawi AA, Yadav D, Mohanta TK.
Molecules. 2018 Mar 14;23(3). pii: E655. doi: 10.3390/molecules23030655.
 
Antitumour, Antimicrobial, Antioxidant and Antiacetylcholinesterase Effect of Ganoderma Lucidum Terpenoids and Polysaccharides: A Review.
Cör D, Knez Ž, Knez Hrnčič M.
Molecules. 2018 Mar 13;23(3). pii: E649. doi: 10.3390/molecules23030649. Review.
 
Ganoderic acid A potentiates the antioxidant effect and protection of mitochondrial membranes and reduces the apoptosis rate in primary hippocampal neurons in magnesium free medium.
Jiang ZM, Qiu HB, Wang SQ, Guo J, Yang ZW, Zhou SB.
Pharmazie. 2018 Feb 1;73(2):87-91. doi: 10.1691/ph.2018.7108.
 
Protective effects of a Ganoderma atrum polysaccharide against acrylamide induced oxidative damage via a mitochondria mediated intrinsic apoptotic pathway in IEC-6 cells.
Jiang G, Zhang L, Wang H, Chen Q, Wu X, Yan X, Chen Y, Xie M.
Food Funct. 2018 Feb 21;9(2):1133-1143. doi: 10.1039/c7fo01619k.
 
Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), as a Cardioprotectant in an Oxygen-Deficient Environment.
Kirar V, Nehra S, Mishra J, Rakhee R, Saraswat D, Misra K.
Int J Med Mushrooms. 2017;19(11):1009-1021. doi: 10.1615/IntJMedMushrooms.2017024584.
 
Analysis of Antioxidant and Anti-Inflammatory Activities of Solvent Fractions from <i>Rhynchosia nulubilis</i> Cultivated with <i>Ganoderma lucidum</i> Mycelium.
Park M, Kim M.
Prev Nutr Food Sci. 2017 Dec;22(4):365-371. doi: 10.3746/pnf.2017.22.4.365. Epub 2017 Dec 31.
 
Ganoderma Lucidum Protects Rat Brain Tissue Against Trauma-Induced Oxidative Stress.
Özevren H, İrtegün S, Deveci E, Aşır F, Pektanç G, Deveci Ş.
Korean J Neurotrauma. 2017 Oct;13(2):76-84. doi: 10.13004/kjnt.2017.13.2.76. Epub 2017 Oct 31.
 
Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Inhibits Candida Biofilms: A Metabolomic Approach.
Bhardwaj A, Gupta P, Kumar N, Mishra J, Kumar A, Rakhee R, Misra K.
Int J Med Mushrooms. 2017;19(8):685-696. doi: 10.1615/IntJMedMushrooms.2017021225.
 
The inhibitory effects of polysaccharide peptides (PsP) of <i>Ganoderma lucidum</i> against atherosclerosis in rats with dyslipidemia.
Wihastuti TA, Heriansyah T.
Heart Int. 2017 Apr 12;12(1):e1-e7. doi: 10.5301/heartint.5000234. eCollection 2017 Jan-Dec.
 
Culture broth of <i>Ganoderma lucidum</i> exhibited antioxidant, antibacterial and α-amylase inhibitory activities.
Sarnthima R, Khammaung S, Sa-Ard P.
J Food Sci Technol. 2017 Oct;54(11):3724-3730. doi: 10.1007/s13197-017-2839-6. Epub 2017 Sep 7.
 
Effect of heat stress on production and in-vitro antioxidant activity of polysaccharides in Ganoderma lucidum.
Tan X, Sun J, Xu Z, Li H, Hu J, Ning H, Qin Z, Pei H, Sun T, Zhang X.
Bioprocess Biosyst Eng. 2018 Jan;41(1):135-141. doi: 10.1007/s00449-017-1850-7. Epub 2017 Oct 10.
 
Retraction Notice: Liquid Fermentation of <i>Ganoderma applanatum</i> and Antioxidant Activity of Exopolysaccharides.
Zhong-Hua L, Xiao-Ge H, Jin-Hui Z, Le HE.
Open Biomed Eng J. 2016 Dec 30;10:114. doi: 10.2174/1874120701610010114. eCollection 2016.
 
Effects of Ganoderma lucidum polysaccharides against doxorubicin-induced cardiotoxicity.
Xu F, Li X, Xiao X, Liu LF, Zhang L, Lin PP, Zhang SL, Li QS.
Biomed Pharmacother. 2017 Nov;95:504-512. doi: 10.1016/j.biopha.2017.08.118. Epub 2017 Sep 12.
 
Ornithine Decarboxylase-Mediated Production of Putrescine Influences Ganoderic Acid Biosynthesis by Regulating Reactive Oxygen Species in Ganoderma lucidum.
Wu CG, Tian JL, Liu R, Cao PF, Zhang TJ, Ren A, Shi L, Zhao MW.
Appl Environ Microbiol. 2017 Sep 29;83(20). pii: e01289-17. doi: 10.1128/AEM.01289-17. Print 2017 Oct 15.
 
The potential of Ganoderma lucidum extracts as bioactive ingredients in topical formulations, beyond its nutritional benefits.
Taofiq O, Heleno SA, Calhelha RC, Alves MJ, Barros L, González-Paramás AM, Barreiro MF, Ferreira ICFR.
Food Chem Toxicol. 2017 Oct;108(Pt A):139-147. doi: 10.1016/j.fct.2017.07.051. Epub 2017 Jul 29.
 
Wild Mushrooms: A Potential Source of Nutritional and Antioxidant Attributes with Acceptable Toxicity.
Sharif S, Shahid M, Mushtaq M, Akram S, Rashid A.
Prev Nutr Food Sci. 2017 Jun;22(2):124-130. doi: 10.3746/pnf.2017.22.2.124. Epub 2017 Jun 30.
 
Protective effect of Ganoderma lucidum polysaccharide against carbon tetrachloride-induced hepatic damage in precision-cut carp liver slices.
Liu Y, Zhang C, Du J, Jia R, Cao L, Jeney G, Teraoka H, Xu P, Yin G.
Fish Physiol Biochem. 2017 Oct;43(5):1209-1221. doi: 10.1007/s10695-016-0333-0. Epub 2017 Jul 5.
 
Anti-amnesic effects of Ganoderma species: A possible cholinergic and antioxidant mechanism.
Kaur R, Singh V, Shri R.
Biomed Pharmacother. 2017 Aug;92:1055-1061. doi: 10.1016/j.biopha.2017.06.029. Epub 2017 Jun 10.
 
Effect of electromagnetic fields and antioxidants on the trace element content of rat teeth.
Dogan MS, Yavas MC, Yavuz Y, Erdogan S, Yener İ, Simsek İ, Akkus Z, Eratilla V, Tanik A, Akdag MZ.
Drug Des Devel Ther. 2017 May 4;11:1393-1398. doi: 10.2147/DDDT.S132308. eCollection 2017.
 
Chemical composition, antiproliferative and antioxidant activity of differently processed <i>Ganoderma lucidum</i> ethanol extracts.
Veljović S, Veljović M, Nikićević N, Despotović S, Radulović S, Nikšić M, Filipović L.
J Food Sci Technol. 2017 Apr;54(5):1312-1320. doi: 10.1007/s13197-017-2559-y. Epub 2017 Mar 10.
 
Structure and bioactivities of a polysaccharide isolated from Ganoderma lucidum in submerged fermentation.
Ai-Lati A, Liu S, Ji Z, Zhang H, Mao J.
Bioengineered. 2017 Sep 3;8(5):565-571. doi: 10.1080/21655979.2017.1283459. Epub 2017 Jan 31.
 
Ganoderma lucidum polysaccharides protect fibroblasts against UVB-induced photoaging.
Zeng Q, Zhou F, Lei L, Chen J, Lu J, Zhou J, Cao K, Gao L, Xia F, Ding S, Huang L, Xiang H, Wang J, Xiao Y, Xiao R, Huang J.
Mol Med Rep. 2017 Jan;15(1):111-116. doi: 10.3892/mmr.2016.6026. Epub 2016 Dec 12.
 
Ganoderma atrum polysaccharide ameliorates ROS generation and apoptosis in spleen and thymus of immunosuppressed mice.
Li WJ, Li L, Zhen WY, Wang LF, Pan M, Lv JQ, Wang F, Yao YF, Nie SP, Xie MY.
Food Chem Toxicol. 2017 Jan;99:199-208. doi: 10.1016/j.fct.2016.11.033. Epub 2016 Nov 30.
 
Ethanol Extract of Ganoderma lucidum Augments Cellular Anti-oxidant Defense through Activation of Nrf2/HO-1.
Lee YH, Kim JH, Song CH, Jang KJ, Kim CH, Kang JS, Choi YH, Yoon HM.
J Pharmacopuncture. 2016 Mar;19(1):59-69. doi: 10.3831/KPI.2016.19.008.
 
Purification, structural characterization and in vitro antioxidant activity of a novel polysaccharide from Boshuzhi.
Jiang J, Kong F, Li N, Zhang D, Yan C, Lv H.
Carbohydr Polym. 2016 Aug 20;147:365-71. doi: 10.1016/j.carbpol.2016.04.001. Epub 2016 Apr 2.
 
Chemical Characterization and Antioxidant Potential of Wild Ganoderma Species from Ghana.
Obodai M, Mensah DL, Fernandes Â, Kortei NK, Dzomeku M, Teegarden M, Schwartz SJ, Barros L, Prempeh J, Takli RK, Ferreira IC.
Molecules. 2017 Jan 25;22(2). pii: E196. doi: 10.3390/molecules22020196.
 
Ganoderma atrum polysaccharide ameliorates anoxia/reoxygenation-mediated oxidative stress and apoptosis in human umbilical vein endothelial cells.
Zhang YS, Li WJ, Zhang XY, Yan YX, Nie SP, Gong DM, Tang XF, He M, Xie MY.
Int J Biol Macromol. 2017 May;98:398-406. doi: 10.1016/j.ijbiomac.2017.01.071. Epub 2017 Jan 17.
 
Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps.
Cilerdzic J, Stajic M, Zivkovic L, Vukojevic J, Bajic V, Spremo-Potparevic B.
Int J Med Mushrooms. 2016;18(12):1061-1069. doi: 10.1615/IntJMedMushrooms.v18.i12.10.
 
Effects of Ganoderma lucidum polysaccharides on chronic pancreatitis and intestinal microbiota in mice.
Li K, Zhuo C, Teng C, Yu S, Wang X, Hu Y, Ren G, Yu M, Qu J.
Int J Biol Macromol. 2016 Dec;93(Pt A):904-912. doi: 10.1016/j.ijbiomac.2016.09.029. Epub 2016 Sep 9.
 
Effect of Oral Coadministration of Ascorbic Acid with Ling Zhi Preparation on Pharmacokinetics of Ganoderic Acid A in Healthy Male Subjects: A Randomized Crossover Study.
Tawasri P, Ampasavate C, Tharatha S, Chiranthanut N, Teekachunhatean S.
Biomed Res Int. 2016;2016:2819862. Epub 2016 Sep 25.
 
Involvement of metabolites in early defense mechanism of oil palm (Elaeis guineensis Jacq.) against Ganoderma disease.
Nusaibah SA, Siti Nor Akmar A, Idris AS, Sariah M, Mohamad Pauzi Z.
Plant Physiol Biochem. 2016 Dec;109:156-165. doi: 10.1016/j.plaphy.2016.09.014. Epub 2016 Sep 19.
 
Comparison of the Chemical Profiles and Antioxidant and Antidiabetic Activities of Extracts from Two Ganoderma Species (Agaricomycetes).
Tang X, Cai W, Xu B.
Int J Med Mushrooms. 2016;18(7):609-20.
 
Species of Genus Ganoderma (Agaricomycetes) Fermentation Broth: A Novel Antioxidant and Antimicrobial Agent.
Cilerdzic J, Kosanic M, Stajić M, Vukojevic J, Ranković B.
Int J Med Mushrooms. 2016;18(5):397-404.
 
Transubstantiating commercial mushroom market with ultrasonically ultrasized mushroom powders showcasing higher bioactivity.
Shang X, Enkhtaivan G, Chun S, Gopal J, Keum YS.
Int J Biol Macromol. 2016 Nov;92:1082-1094. doi: 10.1016/j.ijbiomac.2016.07.103. Epub 2016 Aug 5.
 
Diversity of Polypore Bracket Mushrooms, Polyporales (Agaricomycetes), Recorded in Armenia and Their Medicinal Properties.
Badalyan SM, Gharibyan NG.
Int J Med Mushrooms. 2016;18(4):347-54. doi: 10.1615/IntJMedMushrooms.v18.i4.80.
 
Protective roles of polysaccharides from Ganoderma lucidum on bleomycin-induced pulmonary fibrosis in rats.
Chen J, Shi Y, He L, Hao H, Wang B, Zheng Y, Hu C.
Int J Biol Macromol. 2016 Nov;92:278-281. doi: 10.1016/j.ijbiomac.2016.07.005. Epub 2016 Jul 2.
 
Ganoderma Lucidum polysaccharides protect against MPP(+) and rotenone-induced apoptosis in primary dopaminergic cell cultures through inhibiting oxidative stress.
Guo SS, Cui XL, Rausch WD.
Am J Neurodegener Dis. 2016 Jun 1;5(2):131-44. eCollection 2016 Jun 1.
 
Screening of Indian Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes): A UPC2-SQD-MS Approach.
Bhardwaj A, Srivastava M, Pal M, Sharma YK, Bhattacharya S, Tulsawani R, Sugadev R, Misra K.
Int J Med Mushrooms. 2016;18(2):177-89. doi: 10.1615/IntJMedMushrooms.v18.i2.80.
 
Ultrasonically extracted β-d-glucan from artificially cultivated mushroom, characteristic properties and antioxidant activity.
Alzorqi I, Sudheer S, Lu TJ, Manickam S.
Ultrason Sonochem. 2017 Mar;35(Pt B):531-540. doi: 10.1016/j.ultsonch.2016.04.017. Epub 2016 Apr 26.
 
Antioxidant farnesylated hydroquinones from Ganoderma capense.
Peng X, Li L, Wang X, Zhu G, Li Z, Qiu M.
Fitoterapia. 2016 Jun;111:18-23. doi: 10.1016/j.fitote.2016.04.006. Epub 2016 Apr 13.
 
Optimization of ultrasound induced emulsification on the formulation of palm-olein based nanoemulsions for the incorporation of antioxidant β-D-glucan polysaccharides.
Alzorqi I, Ketabchi MR, Sudheer S, Manickam S.
Ultrason Sonochem. 2016 Jul;31:71-84. doi: 10.1016/j.ultsonch.2015.12.004. Epub 2015 Dec 8.
 
Antioxidant and anticholinesterase activities of five wild mushroom species with total bioactive contents.
Tel G, Ozturk M, Duru ME, Turkoglu A.
Pharm Biol. 2015 Feb 27:1-7. 
 
Biochemical characterization and antioxidant and antiproliferative activities of different ganoderma collections.
Saltarelli R, Ceccaroli P, Buffalini M, Vallorani L, Casadei L, Zambonelli A, Iotti M, Badalyan S, Stocchi V.
J Mol Microbiol Biotechnol. 2015;25(1):16-25. doi: 10.1159/000369212. Epub 2015 Feb 3.
 
Structural characterization and antioxidant activity of a heteropolysaccharide from Ganoderma capense.
Yi P, Li N, Wan JB, Zhang D, Li M, Yan C.
Carbohydr Polym. 2015 May 5;121:183-9. doi: 10.1016/j.carbpol.2014.11.034. Epub 2014 Nov 24.
 
Anti-inflammatory and hepatoprotective effects of Ganoderma lucidum polysaccharides on carbon tetrachloride-induced hepatocyte damage in common carp (Cyprinus carpio L.).
Liu YJ, Du JL, Cao LP, Jia R, Shen YJ, Zhao CY, Xu P, Yin GJ.
Int Immunopharmacol. 2015 Mar;25(1):112-20. doi: 10.1016/j.intimp.2015.01.023. Epub 2015 Jan 29.
 
Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities.
Ferreira IC, Heleno SA, Reis FS, Stojkovic D, Queiroz MJ, Vasconcelos MH, Sokovic M.
Phytochemistry. 2014 Nov 5. pii: S0031-9422(14)00415-4. doi: 10.1016/j.phytochem.2014.10.011. [Epub ahead of print] Review.
 
A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp.
Xia Q, Zhang H, Sun X, Zhao H, Wu L, Zhu D, Yang G, Shao Y, Zhang X, Mao X, Zhang L, She G.
Molecules. 2014 Oct 30;19(11):17478-535. doi: 10.3390/molecules191117478.
 
Fungal beta glucan protects radiation induced DNA damage in human lymphocytes.
Pillai TG, Maurya DK, Salvi VP, Janardhanan KK, Nair CK.
Ann Transl Med. 2014 Feb;2(2):13. doi: 10.3978/j.issn.2305-5839.2014.02.02.
 
Unusual prenylated phenols with antioxidant activities from Ganoderma cochlear.
Peng X, Liu J, Wang C, Han Z, Shu Y, Li X, Zhou L, Qiu M.
Food Chem. 2015 Mar 15;171:251-7. doi: 10.1016/j.foodchem.2014.08.127. Epub 2014 Sep 8.
 
The level of elements and antioxidant activity of commercial dietary supplement formulations based on edible mushrooms.
Stilinović N, Škrbić B, Živančev J, Mrmoš N, Pavlović N, Vukmirović S.
Food Funct. 2014 Dec;5(12):3170-8. doi: 10.1039/c4fo00703d.
 
Modulatory effect of crude aqueous extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes), on hematological and antioxidant indices in Plasmodium berghei-infected mice.
Oluba OM, Adebisi KE, Eidangbe GO, Odutuga AA, Onyeneke EC.
Int J Med Mushrooms. 2014;16(5):499-506.
 
Development of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (Higher Basidiomycetes) polysaccharides injection formulation.
Jiang Y, He A, Liu Y, Xie B, Li Y, Deng Y, Liu X, Liu Q.
Int J Med Mushrooms. 2014;16(5):411-9.
 
Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells.
Choi S, Nguyen VT, Tae N, Lee S, Ryoo S, Min BS, Lee JH.
Toxicol Appl Pharmacol. 2014 Nov 1;280(3):434-42. doi: 10.1016/j.taap.2014.09.007. Epub 2014 Sep 16.
 
Antioxidant activity of polysaccharide extracted from Ganoderma lucidum using response surface methodology.
Kan Y, Chen T, Wu Y, Wu J, Wu J.
Int J Biol Macromol. 2015 Jan;72:151-7. doi: 10.1016/j.ijbiomac.2014.07.056. Epub 2014 Aug 19.
 
Optimization of laccase production by two strains of Ganoderma lucidum using phenolic and metallic inducers.
Kuhar F, Papinutti L.
Rev Argent Microbiol. 2014 Apr-Jun;46(2):144-9. doi: 10.1016/S0325-7541(14)70063-X.
 
Inflammatory modulation effect of glycopeptide from Ganoderma capense (Lloyd) Teng.
Zhou Y, Chen S, Ding R, Yao W, Gao X.
Mediators Inflamm. 2014;2014:691285. doi: 10.1155/2014/691285. Epub 2014 May 22.
 
Solid-substrate fermentation of wheat grains by mycelia of indigenous species of the genus Ganoderma (higher Basidiomycetes) to enhance the antioxidant activities.
Subramaniam S, Sabaratnam V, Kuppusamy UR, Tan YS.
Int J Med Mushrooms. 2014;16(3):259-67.
 
Biological activity of Ganoderma lucidum basidiocarps cultivated on alternative and commercial substrate.
Cilerdžić J, Vukojević J, Stajić M, Stanojković T, Glamočlija J.
J Ethnopharmacol. 2014 Aug 8;155(1):312-9. doi: 10.1016/j.jep.2014.05.036. Epub 2014 May 29.
 
Improving Training Condition Assessment in Endurance Cyclists: Effects of Ganoderma lucidum and Ophiocordyceps sinensis Dietary Supplementation.
Rossi P, Buonocore D, Altobelli E, Brandalise F, Cesaroni V, Iozzi D, Savino E, Marzatico F.
Evid Based Complement Alternat Med. 2014;2014:979613. doi: 10.1155/2014/979613. Epub 2014 Apr 1.
 
Improved production, purification and bioactivity of a polysaccharide from submerged cultured Ganoderma lucidum.
Zhou H, Liu G, Huang F, Wu X, Yang H.
Arch Pharm Res. 2014 Dec;37(12):1530-7. doi: 10.1007/s12272-014-0391-8. Epub 2014 Apr 16.
 
Wild Mushrooms in Nepal: Some Potential Candidates as Antioxidant and ACE-Inhibition Sources.
Hai Bang T, Suhara H, Doi K, Ishikawa H, Fukami K, Parajuli GP, Katakura Y, Yamashita S, Watanabe K, Adhikari MK, Manandhar HK, Kondo R, Shimizu K.
Evid Based Complement Alternat Med. 2014;2014:195305. doi: 10.1155/2014/195305. Epub 2014 Jan 28.
 
Effects of Selenium-Enriched Protein from Ganoderma lucidum on the Levels of IL-1 β and TNF- α , Oxidative Stress, and NF- κ B Activation in Ovalbumin-Induced Asthmatic Mice.
Min-Chang G, Wei-Hong T, Zhen X, Jie S.
Evid Based Complement Alternat Med. 2014;2014:182817. doi: 10.1155/2014/182817. Epub 2014 Feb 10.
 
Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism.
Phan CW, David P, Naidu M, Wong KH, Sabaratnam V.
Crit Rev Biotechnol. 2014 Mar 24.
 
Acetylation and carboxymethylation of the polysaccharide from Ganoderma atrum and their antioxidant and immunomodulating activities.
Chen Y, Zhang H, Wang Y, Nie S, Li C, Xie M.
Food Chem. 2014 Aug 1;156:279-88. doi: 10.1016/j.foodchem.2014.01.111. Epub 2014 Feb 7.
 
Immunomodulatory of selenium nano-particles decorated by sulfated Ganoderma lucidum polysaccharides.
Wang J, Zhang Y, Yuan Y, Yue T.
Food Chem Toxicol. 2014 Jun;68:183-9. doi: 10.1016/j.fct.2014.03.003. Epub 2014 Mar 10.
 
Ganoderma lucidum polysaccharides supplementation attenuates exercise-induced oxidative stress in skeletal muscle of mice.
Zhonghui Z, Xiaowei Z, Fang F.
Saudi J Biol Sci. 2014 Apr;21(2):119-23. doi: 10.1016/j.sjbs.2013.04.004. Epub 2013 Apr 23.
 
Effect of ultrasonic extraction conditions on antioxidative and immunomodulatory activities of a Ganoderma lucidum polysaccharide originated from fermented soybean curd residue.
Shi M, Yang Y, Hu X, Zhang Z.
Food Chem. 2014 Jul 15;155:50-6. doi: 10.1016/j.foodchem.2014.01.037. Epub 2014 Jan 23.
 
Immunostimulatory activities of β-d-glucan from Ganoderma Lucidum.
Wang J, Yuan Y, Yue T.
Carbohydr Polym. 2014 Feb 15;102:47-54. doi: 10.1016/j.carbpol.2013.10.087. Epub 2013 Nov 6.