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| The acetylation of Ganoderma applanatum polysaccharides on ameliorating T2DM-induced hepatic and colonic injuries by modulating the Nrf2/keap1-TLR4/NFkappaB-Bax/Bcl-2 pathways. |
| Zhang Y, Li X, Xu S, Li J, Shi L, Wang Z, Chen P, Jia L, Zhang J. |
| Int J Biol Macromol. 2025 Mar;294:140055. doi: 10.1016/j.ijbiomac.2025.140055. Epub 2025 Jan 17. |
| Green tea fermented by Ganoderma lucidum presented anti-obesity properties via enhanced thermogenesis in vitro and on C57BL/6J mice. |
| Liu X, Ju Y, Zeng H, Wen S, Wang C, Jiang M, Tian B, Huang J, Liu Z. |
| Food Res Int. 2025 Apr;207:116092. doi: 10.1016/j.foodres.2025.116092. Epub 2025 Feb 25. |
| The Protective Effects of Ganoderma lucidum Active Peptide GLP4 on Lung Injury Induced by Cadmium Poisoning in Mice. |
| Zhu S, Wang X, Liu G. |
| Toxics. 2024 May 22;12(6):378. doi: 10.3390/toxics12060378. |
| Alcoholic Extracts from the Ganoderma Lucidum Fermentation Product Alleviated Ethanol-Induced Liver Injury, Gut Leakiness, and Gut Dysbiosis in Mice. |
| Zhao Z, Ma X, Li M, Chen G, Qi L, Song S, Li Z, Yan C. |
| Plant Foods Hum Nutr. 2024 Dec 5;80(1):2. doi: 10.1007/s11130-024-01271-x. |
| The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts. |
| Li K, Liu W, Wu C, Wang L, Huang Y, Li Y, Zheng H, Shang Y, Zhang L, Chen Z. |
| Heliyon. 2024 May 8;10(10):e30907. doi: 10.1016/j.heliyon.2024.e30907. eCollection 2024 May 30. |
| High molecular weight polysaccharides from Ganoderma lucidum attenuates inflammatory responses, gut microbiota, and liver metabolomic in lipopolysaccharide-induced liver injury mice. |
| Guo W, Liu W, Liang P, Ni L, Lv X, Fan J, Shi F. |
| Int J Biol Macromol. 2025 Jan;287:138400. doi: 10.1016/j.ijbiomac.2024.138400. Epub 2024 Dec 8. |
| Clinical Evaluation of Ganoderma lucidum Spore Oil for Triglyceride Reduction: A Randomized, Double-Blind, Crossover Study. |
| Wang X, Wang X, Zhao L, Zhou F. |
| Nutrients. 2025 Feb 28;17(5):844. doi: 10.3390/nu17050844. |
| Ganoderma lucidum Spore Powder Alleviates Metabolic-Associated Fatty Liver Disease by Improving Lipid Accumulation and Oxidative Stress via Autophagy. |
| Zhang Y, Zhou J, Yang L, Xiao H, Liu D, Kang X. |
| Antioxidants (Basel). 2024 Dec 9;13(12):1501. doi: 10.3390/antiox13121501. |
| Ganoderma pfeifferi Bres. and Ganoderma resinaceum Boud. as Potential Therapeutic Agents: A Comparative Study on Antiproliferative and Lipid-Lowering Properties. |
| Rašeta M, Kebert M, Mišković J, Kostić S, Kaišarević S, Stilinović N, Vukmirović S, Karaman M. |
| J Fungi (Basel). 2024 Jul 19;10(7):501. doi: 10.3390/jof10070501. |
| Ganoderma lucidum Polysaccharides Ameliorate Acetaminophen-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Apoptosis along the Nrf2 Pathway. |
| Zhang N, Han Z, Zhang R, Liu L, Gao Y, Li J, Yan M. |
| Nutrients. 2024 Jun 13;16(12):1859. doi: 10.3390/nu16121859. |
| Lingzhi, Reishi. |
| [No authors listed] |
| 2024 Oct 5. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. |
| Ganoderma lucidum polysaccharides reduce the severity of acute liver injury by improving the diversity and function of the gut microbiota. |
| Zhang XT, Yang Y, Ji C, Fu Y, Pu X, Xu G. |
| Heliyon. 2024 Aug 2;10(15):e35559. doi: 10.1016/j.heliyon.2024.e35559. eCollection 2024 Aug 15. |
| Triterpenes from Ganoderma lucidum inhibit hepatocellular carcinoma by regulating enhancer-associated lncRNA in vivo. |
| Zhao R, Zhang C, Tang C, Wu X, Hu S, Luo Q, Jia N, Fan L, Wang Y, Jiang W, Chen Q. |
| J Ethnopharmacol. 2025 Jan 10;336:118706. doi: 10.1016/j.jep.2024.118706. Epub 2024 Aug 24. |
| Ganoderma lucidum spore oil attenuates acute liver injury by modulating lipid metabolism and gut microbiota. |
| Liu J, Chen Y, Cen Z, Hong M, Zhang B, Luo X, Wang L, Li S, Xiao X, Long Q. |
| J Pharm Biomed Anal. 2025 Apr 15;256:116674. doi: 10.1016/j.jpba.2025.116674. Epub 2025 Jan 16. |
| Potential of natural products and gut microbiome in tumor immunotherapy. |
| Cao L, Wang X, Ma X, Xu M, Li J. |
| Chin Med. 2024 Nov 20;19(1):161. doi: 10.1186/s13020-024-01032-7. |
| Research Progress on the Biological Activity of Ganoderic Acids in Ganoderma lucidum over the Last Five Years. |
| Wang S, Wang L, Shangguan J, Jiang A, Ren A. |
| Life (Basel). 2024 Oct 21;14(10):1339. doi: 10.3390/life14101339. |
| Structure Identification of Ganoderma lucidum Spore Polysaccharides and Their Antitumor Activity In Vivo. |
| Liu HM, Cheng J, Wang XY, Jiang Y, Ni J, Zhang Y, Wang W. |
| Molecules. 2024 May 16;29(10):2348. doi: 10.3390/molecules29102348. |
| Bioactivities and industrial standardization status of Ganoderma lucidum: A comprehensive review. |
| Wu P, Zhang C, Yin Y, Zhang X, Li Q, Yuan L, Sun Y, Zhou S, Ying S, Wu J. |
| Heliyon. 2024 Aug 29;10(19):e36987. doi: 10.1016/j.heliyon.2024.e36987. eCollection 2024 Oct 15. |
| Ganoderma tsuage promotes pain sensitivity in aging mice. |
| Yang KN, Lin CY, Li WN, Tang CM, Pradhan J, Chao MW, Tseng CY. |
| Sci Rep. 2024 May 21;14(1):11536. doi: 10.1038/s41598-024-61499-0. |
| Enhancement of exercise-induced fatigue alleviation and liver selenium regulation through in situ nanoselenium synthesis by Lactobacillus rhamnosus cells, empowered by Ganoderma lucidum spore loading. |
| Shi D, Xu F, Li Y, Shang X, Liao N, Jin H, Liu G, Shao D. |
| J Food Sci. 2024 Nov;89(11):7992-8005. doi: 10.1111/1750-3841.17392. Epub 2024 Oct 4. |
| Inhibition of Hepatoblastoma by Ganoderma Lucidum Polysaccharide via the Induction of HDAC4-p16-RB Axis-Mediated Cellular Senescence. |
| Ye T, Ge Y, Zhang J, Gao H, Zhang PC, Shen R, Peng C, Liu B, Song H. |
| Phytother Res. 2025 Apr 6. doi: 10.1002/ptr.8493. Online ahead of print. |
| Ganoderma lucidum Polysaccharide/carboxymethyl Chitosan Hydrogels Modulate Macrophage Polarization for Wound Healing. |
| Zou Y, Yang Y, Pei J, Sun P, Wang Y. |
| Biomacromolecules. 2025 Apr 14;26(4):2675-2689. doi: 10.1021/acs.biomac.5c00112. Epub 2025 Mar 28. |
| [Chemical composition analysis of Ganoderma lucidum based on UPLC-Orbitrap-HRMS and virtual screening of FXR activators for treatment of liver fibrosis]. |
| Zhang J, Li SY, Luo WH, Wang J, Beng SJ, Han HL, Xiong QP, Peng DY, Peng C. |
| Zhongguo Zhong Yao Za Zhi. 2024 Jul;49(14):3804-3817. doi: 10.19540/j.cnki.cjcmm.20240405.205. |
| Ganoderma lucidum polysaccharide promotes broiler health by regulating lipid metabolism, antioxidants, and intestinal microflora. |
| Gao YY, Zhou YH, Liu XP, Di B, He JY, Wang YT, Guo PT, Zhang J, Wang CK, Jin L. |
| Int J Biol Macromol. 2024 Sep 23;280(Pt 3):135918. doi: 10.1016/j.ijbiomac.2024.135918. Online ahead of print. |
| Association of alpha-Klotho with anti-aging effects of Ganoderma lucidum in animal models. |
| Liu X, Zhao J, Liu J, Huang Y, Deng W, Yan L, Cui M, Pan X, Xiao H, Liu X. |
| J Ethnopharmacol. 2025 Apr 9;345:119597. doi: 10.1016/j.jep.2025.119597. Epub 2025 Mar 7. |
| Medicinal Mushrooms in Metastatic Breast Cancer: What Is Their Therapeutic Potential as Adjuvant in Clinical Settings? |
| De Luca F, Roda E, Rossi P, Bottone MG. |
| Curr Issues Mol Biol. 2024 Jul 17;46(7):7577-7591. doi: 10.3390/cimb46070450. |
| Triterpenes from antler-shaped fruiting body of Ganoderma lucidum and their hepatoprotective activities. |
| Shao H, Li Y, Wu C, Chen R, Kang J. |
| Phytochemistry. 2024 Aug;224:114148. doi: 10.1016/j.phytochem.2024.114148. Epub 2024 May 18. |
| In vitro antitumor effects of methanolic extracts of three Ganoderema mushrooms. |
| Toson EA, El-Fallal AA, Oransa MA, El-Gharabawy HM. |
| Sci Rep. 2025 Jan 17;15(1):2274. doi: 10.1038/s41598-025-86162-0. |
| Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of Ganoderma lucidum. |
| Xu X, Li C, Wu F, Zhao S, Chen T, You H, Lin Y, Zou X. |
| J Fungi (Basel). 2025 Jan 13;11(1):57. doi: 10.3390/jof11010057. |
| Unveiling the anticancer potential and toxicity of Ganoderma applanatum wild mushroom derived bioactive compounds: An in vitro, in vivo and in silico evaluation. |
| Rijia A, Krishnamoorthi R, Mahalingam PU, Kaviyadharshini M, Rajeswari M, Kumar KKS, Rasmi M, Chung YK, Fang JY. |
| Bioorg Chem. 2025 Mar;156:108233. doi: 10.1016/j.bioorg.2025.108233. Epub 2025 Jan 31. |
| Spore Oil enhances the effect of cyclophosphamide inhibiting programmed death-1 and prolongs the survival of H22 tumor-bearing mice. |
| Zhaojian J, Hongfei C, Cheng Y, Lin C, Wendong XU, Yaming H, Qin Z, Jing LI, Qin W, Juyan L. |
| J Tradit Chin Med. 2024 Aug;44(4):652-659. doi: 10.19852/j.cnki.jtcm.2024.04.003. |
| Anti-inflammatory effects of para-quinone methide derivatives on ulcerative colitis. |
| Qiu Y, Li X, Zhang X, Wang X, Wang X, Yang J, Liu G. |
| Front Pharmacol. 2024 Oct 29;15:1474678. doi: 10.3389/fphar.2024.1474678. eCollection 2024. |
| Synthesis of Ganoderic Acids Loaded Zein-Chitosan Nanoparticles and Evaluation of Their Hepatoprotective Effect on Mice Given Excessive Alcohol. |
| Cao Y, Yang Y, Liang Z, Guo W, Lv X, Ni L, Chen Y. |
| Foods. 2024 Aug 29;13(17):2760. doi: 10.3390/foods13172760. |
| Early Preclinical Studies of Ergosterol Peroxide and Biological Evaluation of Its Derivatives. |
| Ling T, Arroyo-Cruz LV, Smither WR, Seighman EK, Martínez-Montemayor MM, Rivas F. |
| ACS Omega. 2024 Aug 19;9(35):37117-37127. doi: 10.1021/acsomega.4c04350. eCollection 2024 Sep 3. |
| Functional properties of Ganoderma lucidum supplementation in canine nutrition. |
| Kayser E, Castaneda PL, Soto-Diaz K, Steelman AJ, Murphy A, Spindola M, He F, de Godoy MRC. |
| J Anim Sci. 2024 Feb 28:skae051. doi: 10.1093/jas/skae051. Online ahead of print. |
| Ganoderma lingzhi (Reishi Mushroom)-Induced Acute Liver Injury in the Setting of Alcohol Use: A Case Report and Review of the Literature. |
| Guedikian R, Kim B, Singh G, Alexander R. |
| Cureus. 2023 Sep 25;15(9):e45953. doi: 10.7759/cureus.45953. eCollection 2023 Sep. |
| G. lucidum triterpenes restores intestinal flora balance in non-hepatitis B virus-related hepatocellular carcinoma: evidence of 16S rRNA sequencing and network pharmacology analysis. |
| Xiong W, Yang C, Xia J, Wang W, Li N. |
| Front Pharmacol. 2023 Sep 18;14:1197418. doi: 10.3389/fphar.2023.1197418. eCollection 2023. |
| Ganoderma lucidum: Novel Insight into Hepatoprotective Potential with Mechanisms of Action. |
| Ahmad MF, Ahmad FA, Zeyaullah M, Alsayegh AA, Mahmood SE, AlShahrani AM, Khan MS, Shama E, Hamouda A, Elbendary EY, Attia KAHA. |
| Nutrients. 2023 Apr 13;15(8):1874. doi: 10.3390/nu15081874. |
| Network pharmacology-based analysis of Resinacein S against non-alcoholic fatty liver disease by modulating lipid metabolism. |
| Mao FF, Gao SS, Huang YJ, Zhou N, Feng JK, Liu ZH, Zhang YQ, Yuan LY, Wei G, Cheng SQ. |
| Front Nutr. 2023 Feb 14;10:1076569. doi: 10.3389/fnut.2023.1076569. eCollection 2023. |
| Cytotoxic Activities and Fingerprint Analysis of Triterpenes by HPTLC Technique for Distinguishing Ganoderma Species from Vietnam and other Asian Countries. |
| Viet Hung T, Thang PNT, Hien HM, Diep VT, Thu NT, Tan DM, Pham DT, Thi Ha D, Huynh DTM. |
| Plants (Basel). 2022 Dec 6;11(23):3397. doi: 10.3390/plants11233397. |
| Innovative prophylactic and therapeutic approaches in liver cirrhosis. |
| Ciovicescu LM, Clichici SV, Simedrea RA, Ciovicescu F, Lupan SC, Sabău LI, Toader AM, Mocan T. |
| Physiol Int. 2024 Feb 29;111(1):1-18. doi: 10.1556/2060.2024.00339. Print 2024 Mar 21. |
| Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning. |
| Xiao C, Huang G, Cao X, Li X. |
| Am J Transl Res. 2024 Jan 15;16(1):295-303. eCollection 2024. |
| Polysaccharides from Chinese herbal medicine: a review on the hepatoprotective and molecular mechanism. |
| Li J, Guo H, Dong Y, Yuan S, Wei X, Zhang Y, Dong L, Wang F, Bai T, Yang Y. |
| Chin J Nat Med. 2024 Jan;22(1):4-14. doi: 10.1016/S1875-5364(24)60558-3. |
| Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner. |
| Huang D, Shen S, Zhuang Q, Ye X, Qian Y, Dong Z, Wan X. |
| Chin Med. 2024 Jan 24;19(1):16. doi: 10.1186/s13020-024-00889-y. |
| Ganoderma lucidum ethanol extracts ameliorate hepatic fibrosis and promote the communication between metabolites and gut microbiota g_Ruminococcus through the NF-kappaB and TGF-beta1/Smads pathways. |
| Zhang J, Wang W, Cui X, Zhu P, Li S, Yuan S, Peng D, Peng C. |
| J Ethnopharmacol. 2024 Mar 25;322:117656. doi: 10.1016/j.jep.2023.117656. Epub 2023 Dec 26. |
| Compound chenpi tea consumption reduces obesity-related metabolic disorders by modulating gut microbiota and serum metabolites in mice. |
| Wang J, Hao J, Miao D, Xiao P, Jiang X, E-Hu L. |
| J Sci Food Agric. 2024 Jan 15;104(1):431-442. doi: 10.1002/jsfa.12940. Epub 2023 Sep 14. |
| Amelioration of CCl(4)-induced oxidative stress and hepatotoxicity by Ganoderma lucidum in long evans rats. |
| Johra FT, Hossain S, Jain P, Bristy AT, Emran T, Ahmed R, Sharker SM, Bepari AK, Reza HM. |
| Sci Rep. 2023 Jun 19;13(1):9909. doi: 10.1038/s41598-023-35228-y. |
| Ganoderma lucidum polysaccharide inhibits HSC activation and liver fibrosis via targeting inflammation, apoptosis, cell cycle, and ECM-receptor interaction mediated by TGF-beta/Smad signaling. |
| Chen C, Chen J, Wang Y, Fang L, Guo C, Sang T, Peng H, Zhao Q, Chen S, Lin X, Wang X. |
| Phytomedicine. 2023 Feb;110:154626. doi: 10.1016/j.phymed.2022.154626. Epub 2022 Dec 24. |
| Ganoderma lucidum polysaccharide peptide alleviates hyperuricemia by regulating adenosine deaminase and urate transporters. |
| Lin S, Meng J, Li F, Yu H, Lin D, Lin S, Li M, Zhou H, Yang B. |
| Food Funct. 2022 Dec 13;13(24):12619-12631. doi: 10.1039/d2fo02431d. |
| Christensenella regulated by Huang-Qi-Ling-Hua-San is a key factor by which to improve type 2 diabetes. |
| Pan T, Zheng S, Zheng W, Shi C, Ning K, Zhang Q, Xie Y, Xiang H, Xie Q. |
| Front Microbiol. 2022 Oct 12;13:1022403. doi: 10.3389/fmicb.2022.1022403. eCollection 2022. |
| Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance. |
| Li H, Du Y, Ji H, Yang Y, Xu C, Li Q, Ran L, Wu C, Zhou Q, Wu S. |
| iScience. 2022 Sep 26;25(11):105214. doi: 10.1016/j.isci.2022.105214. eCollection 2022 Nov 18. |
| Organic chromium derived from the chelation of Ganoderma lucidum polysaccharide and chromium (III) alleviates metabolic syndromes and intestinal microbiota dysbiosis induced by high-fat and high-fructose diet. |
| Lv XC, Wu Q, Yuan YJ, Li L, Guo WL, Lin XB, Huang ZR, Rao PF, Ai LZ, Ni L. |
| Int J Biol Macromol. 2022 Oct 31;219:964-979. doi: 10.1016/j.ijbiomac.2022.07.211. Epub 2022 Aug 6. |
| Antidiabetic lanostane triterpenoids from the fruiting bodies of Ganoderma weberianum. |
| Yang L, Kong DX, Xiao N, Ma QY, Xie QY, Guo JC, Ying Deng C, Ma HX, Hua Y, Dai HF, Zhao YX. |
| Bioorg Chem. 2022 Oct;127:106025. doi: 10.1016/j.bioorg.2022.106025. Epub 2022 Jul 13. |
| Ganoderma lucidum Modulates Glucose, Lipid Peroxidation and Hepatic Metabolism in Streptozotocin-Induced Diabetic Pregnant Rats. |
| Viroel FJM, Laurino LF, Caetano ÉLA, Jozala AF, Spim SRV, Pickler TB, Sercundes MK, Gomes MC, Hataka A, Grotto D, Gerenutti M. |
| Antioxidants (Basel). 2022 May 24;11(6):1035. doi: 10.3390/antiox11061035. |
| Hypouricemic Effect of Submerged Culture of Ganoderma lucidum in Potassium Oxonate-Induced Hyperuricemic Rats. |
| Huang CH, Chen TY, Tsai GJ. |
| Metabolites. 2022 Jun 16;12(6):553. doi: 10.3390/metabo12060553. |
| Association of gut microbiota characteristics and metabolites reveals the regulation mechanisms under cadmium consumption circumstance. |
| Dai Z, Liu J, Yao X, Wang A, Liu Y, Strappe P, Huang W, Zhou Z. |
| J Sci Food Agric. 2022 Nov;102(14):6737-6748. doi: 10.1002/jsfa.12041. Epub 2022 Jun 21. |
| Ganoderic acid A from Ganoderma lucidum protects against alcoholic liver injury through ameliorating the lipid metabolism and modulating the intestinal microbial composition. |
| Lv XC, Wu Q, Cao YJ, Lin YC, Guo WL, Rao PF, Zhang YY, Chen YT, Ai LZ, Ni L. |
| Food Funct. 2022 May 23;13(10):5820-5837. doi: 10.1039/d1fo03219d. |
| Polysaccharide-Rich Fractions from Ganoderma resinaceum (Ganodermataceae) as Chemopreventive Agents in N-Diethylnitrosamine-Induced Hepatocellular Carcinoma in Wistar Rats. |
| Sipping MTK, Mediesse FK, Kenmogne LV, Kanemoto JEN, Njamen D, Boudjeko T. |
| Evid Based Complement Alternat Med. 2022 Apr 12;2022:8198859. doi: 10.1155/2022/8198859. eCollection 2022. |
| Ganoderic acids-rich ethanol extract from Ganoderma lucidum protects against alcoholic liver injury and modulates intestinal microbiota in mice with excessive alcohol intake. |
| Guo WL, Cao YJ, You SZ, Wu Q, Zhang F, Han JZ, Lv XC, Rao PF, Ai LZ, Ni L. |
| Curr Res Food Sci. 2022 Feb 24;5:515-530. doi: 10.1016/j.crfs.2022.02.013. eCollection 2022. |
| Sporoderm-broken spores of Ganoderma lucidum modulate hepatoblastoma malignancy by regulating RACK1-mediated autophagy and tumour immunity. |
| Shen R, Ge Y, Qin Y, Gao H, Yu H, Wu H, Song H. |
| J Cell Mol Med. 2024 Mar;28(6):e18223. doi: 10.1111/jcmm.18223. |
| COP-22 Alleviates D-Galactose-Induced Brain Aging by Attenuating Oxidative Stress, Inflammation, and Apoptosis in Mice. |
| Ma Y, Wang X, Li X, Chen X, Teng Z, Wang X, Yang J, Liu G. |
| Mol Neurobiol. 2024 Feb 12. doi: 10.1007/s12035-024-03976-1. Online ahead of print. |
| EFFECT OF DRY EXTRACT FROM REISHI MUSHROOMS ON THE STATE OF ANTIOXIDANT SYSTEM IN RATS WITH DMH-INDUCED COLON CARCINOGENESIS. |
| Herasymets I, Fira L, Medvid I, Fira D, Yasinovskyi O, Grytsyshyn L. |
| Wiad Lek. 2023;76(12):2632-2640. doi: 10.36740/WLek202312112. |
| The protective effect of PL 1-3 on D-galactose-induced aging mice. |
| Li P, Ma Y, Wang X, Li X, Wang X, Yang J, Liu G. |
| Front Pharmacol. 2024 Jan 3;14:1304801. doi: 10.3389/fphar.2023.1304801. eCollection 2023. |
| Discovery of a 4-Hydroxy-3'-Trifluoromethoxy-Substituted Resveratrol Derivative as an Anti-Aging Agent. |
| Liang Y, Chen X, Teng Z, Wang X, Yang J, Liu G. |
| Molecules. 2023 Dec 22;29(1):86. doi: 10.3390/molecules29010086. |
| Ganoderma Fusions with High Yield of Ergothioneine and Comparative Analysis of Its Genomics. |
| Xie J, Yu Y, You J, Ye Z, Zhou F, Wang N, Zhong J, Guo L, Lin J. |
| J Fungi (Basel). 2023 Nov 2;9(11):1072. doi: 10.3390/jof9111072. |
| Proteomics and network pharmacology of Ganshu Nuodan capsules in the prevention of alcoholic liver disease. |
| Yang X, Wang L, Cui X, Zhang J, Liang Y, Luo Z, Zhou B, Jiang Z, Yang RYH, Wu Y, Wei K, Du M, Qin S, Dai C, Zhao G. |
| Front Endocrinol (Lausanne). 2023 Sep 18;14:1229777. doi: 10.3389/fendo.2023.1229777. eCollection 2023. |
| Pharmacological Activities and Safety of Ganoderma lucidum Spores: A Systematic Review. |
| Thuy NHL, Tu VL, Thu LNA, Giang TT, Huyen DTK, Loc DH, Tam DNH, Phat NT, Huynh HH, Truyen TTTT, Nguyen QH, Do U, Nguyen D, Dat TV, Minh LHN. |
| Cureus. 2023 Sep 2;15(9):e44574. doi: 10.7759/cureus.44574. eCollection 2023 Sep. |
| Thermal/ultrasound-triggered release of liposomes loaded with Ganoderma applanatum polysaccharide from microbubbles for enhanced tumour ablation. |
| Yuan J, Ding L, Han L, Pang L, Zhang P, Yang X, Liu H, Zheng M, Zhang Y, Luo W. |
| J Control Release. 2023 Nov;363:84-100. doi: 10.1016/j.jconrel.2023.09.030. Epub 2023 Sep 25. |
| Preclinical pharmacokinetics-related pharmacological effects of orally administered polysaccharides from traditional Chinese medicines: A review. |
| Ye D, Zhao Q, Ding D, Ma BL. |
| Int J Biol Macromol. 2023 Dec 1;252:126484. doi: 10.1016/j.ijbiomac.2023.126484. Epub 2023 Aug 23. |
| In vitro cholesterol lowering activity of Ganoderma australe mycelia based on mass spectrometry, synchrotron Fourier-transform infrared analysis and liver-spheroid bioactivity. |
| Wongkhieo S, Tangmesupphaisan W, Siriwaseree J, Aramsirirujiwet Y, Wiriyajitsomboon P, Kaewgrajang T, Pumloifa S, Paemanee A, Kuaprasert B, Choowongkomon K, Chester AH, Swainson NM. |
| Sci Rep. 2023 Aug 21;13(1):13619. doi: 10.1038/s41598-023-40861-8. |
| Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-kappaB and MAPK signaling pathways. |
| Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M. |
| Phytomedicine. 2023 Oct;119:155010. doi: 10.1016/j.phymed.2023.155010. Epub 2023 Aug 2. |
| Inhibitory effects of Ganoderma lucidum triterpenoid on the growth and metastasis of hepatocellular carcinoma. |
| Ding Z, Zhou Z, Cheng X, Wang H, Liu J, Cai Y, Liu H, Lv M, Pan Y, Xiao E. |
| Am J Transl Res. 2023 May 15;15(5):3410-3423. eCollection 2023. |
| The Medicinal Mushroom Ganoderma neo-japonicum (Agaricomycetes) Polysaccharide Extract Prevents Obesity-Induced Diabetes in C57BL/6J Mice. |
| Subramaniam S, Ong KC, Sabaratnam V, Chua KH, Kuppusamy UR. |
| Int J Med Mushrooms. 2023;25(4):27-42. doi: 10.1615/IntJMedMushrooms.2023047595. |
| Silver nanoparticles combat Salmonella Typhimurium: Suppressing intracellular infection and activating dendritic cells. |
| Gong J, Cheng X, Zuo J, Zhang Y, Lin J, Liu M, Jiang Y, Long Y, Si H, Gao X, Guo D, Gu N. |
| Colloids Surf B Biointerfaces. 2023 Jun;226:113307. doi: 10.1016/j.colsurfb.2023.113307. Epub 2023 Apr 10. |
| A tri-herb formulation protects against ethanol-induced mouse liver injury and downregulates mitogen-activated protein kinase phosphatase 1. |
| Chen W, Deng YY, Yu JW, Leung YT, Bai JX, Chen YJ, Wu Y, Wang L, Fan XY, Wang XQ, Hu J, Chen WH, Dou X, Leung KS, Fu XQ, Yu ZL. |
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| Effects of Mexican Ganoderma lucidum extracts on liver, kidney, and the gut microbiota of Wistar rats: A repeated dose oral toxicity study. |
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| Ganoderma terpenoid extract exhibited anti-plasmodial activity by a mechanism involving reduction in erythrocyte and hepatic lipids in Plasmodium berghei infected mice. |
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| Randomized Clinical Trial for the Evaluation of Immune Modulation by Yogurt Enriched with β-Glucans from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Children from Medellin, Colombia. |
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| The effect of Ganoderma lucidum extract on immunological function and identify its anti-tumor immunostimulatory activity based on the biological network. |
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| Ganoderma lucidum Ameliorates Non-Alcoholic Steatosis by Upregulating Energy Metabolizing Enzymes in the Liver. |
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| Ethanol extract of Ganoderma lucidum ameliorates lipid metabolic disorders and modulates the gut microbiota composition in high-fat diet fed rats. |
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| Combinatorial usage of fungal polysaccharides from Cordyceps sinensis and Ganoderma atrum ameliorate drug-induced liver injury in mice. |
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| Evaluation of the Antioxidative and Hypo-cholesterolemic Effects of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Ameliorating Cardiovascular Disease. |
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| Effects of Concurrently Administered Aqueous Extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), and Lead Acetate in Rats. |
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| Protective effects of Ganoderma triterpenoids on cadmium-induced oxidative stress and inflammatory injury in chicken livers. |
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| Anti-Inflammatory and Hepatoprotective Effects of Ganoderma lucidum Polysaccharides against Carbon Tetrachloride-Induced Liver Injury in Kunming Mice. |
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| Effects of Ganoderma lucidum and ‘Essence of Chicken’ on Physical Fatigue Recovery and Exercise Performance Improvement. |
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| Hypoglycemic mechanisms of Ganoderma lucidum polysaccharides F31 in db/db mice via RNA-seq and iTRAQ. |
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| Pharmacological effects of natural Ganoderma and its extracts on neurological diseases: A comprehensive review. |
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| Meroterpenoids from Ganoderma sinense protect hepatocytes and cardiomyocytes from oxidative stress induced injuries. |
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| Fitoterapia. 2018 Nov;131:73-79. doi: 10.1016/j.fitote.2018.10.009. Epub 2018 Oct 9. |
| Hepatoprotective activity of Ganoderma lucidum triterpenoids in alcohol-induced liver injury in mice, an iTRAQ-based proteomic analysis. |
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| Food Chem. 2019 Jan 15;271:148-156. doi: 10.1016/j.foodchem.2018.07.115. Epub 2018 Jul 18. |
| Ganoderma Lucidum Polysaccharide Peptide Alleviates Hepatoteatosis via Modulating Bile Acid Metabolism Dependent on FXR-SHP/FGF. |
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| Hypolipidemic, Antioxidant, and Antiapoptotic Effects of Polysaccharides Extracted from Reishi Mushroom, Ganoderma lucidum (Leysser: Fr) Karst, in Mice Fed a High-Fat Diet. |
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| Hypolipidaemic and anti-lipidperoxidant activities of Ganoderma lucidum polysaccharide. |
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| Antioxidant and Hepatoprotective Activities of Crude Polysaccharide Extracts from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), by Ultrasonic-Circulating Extraction. |
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| Int J Med Mushrooms. 2018;20(6):581-593. doi: 10.1615/IntJMedMushrooms.2018026536. |
| The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death. |
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| Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats. |
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| Hypouricemic Effects of Ganoderma applanatum in Hyperuricemia Mice through OAT1 and GLUT9. |
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| Racemic meroterpenoids from Ganoderma cochlear. |
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| Antidiabetic activity of Ganoderma lucidum polysaccharides F31 down-regulated hepatic glucose regulatory enzymes in diabetic mice. |
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| Hypouricemic Effects of <i>Ganoderma applanatum</i> in Hyperuricemia Mice through OAT1 and GLUT9. |
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| Ganoderic Acid A Metabolites and Their Metabolic Kinetics. |
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| Cytotoxic lanostane-type triterpenoids from the fruiting bodies of Ganoderma lucidum and their structure-activity relationships. |
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| Hypocholesterolemic Properties and Prebiotic Effects of Mexican Ganoderma lucidum in C57BL/6 Mice. |
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| Ganoderma lucidum beta 1,3/1,6 glucan as an immunomodulator in inflammation induced by a high-cholesterol diet. |
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| Hepatoprotective Effects and Mechanisms of Action of Triterpenoids from Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) on α-Amanitin-Induced Liver Injury in Mice. |
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| Int J Med Mushrooms. 2016;18(9):841-850. |
| Lucidumol C, a new cytotoxic lanostanoid triterpene from Ganoderma lingzhi against human cancer cells. |
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| Wound healing activity of an aqueous extract of the Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes). |
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| Biological activity of Ganoderma lucidum basidiocarps cultivated on alternative and commercial substrate. |
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| Screening and isolation for anti-hepatofibrotic components from medicinal mushrooms using TGF-(β1-induced live fibrosis in hepatic stellate cells. |
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| Int J Med Mushrooms. 2014;16(6):529-39. |
| Anti-inflammatory and hepatoprotective effects of Ganoderma lucidum polysaccharides on carbon tetrachloride-induced hepatocyte damage in common carp (Cyprinus carpio L.). |
| Liu YJ, Du JL, Cao LP, Jia R, Shen YJ, Zhao CY, Xu P, Yin GJ. |
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| A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle. |
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| Food Funct. 2014 Jul 25;5(7):1389-94. doi: 10.1039/c4fo00258j. |
| An Immunomodulatory Protein (Ling Zhi-8) from a Ganoderma lucidum Induced Acceleration of Wound Healing in Rat Liver Tissues after Monopolar Electrosurgery. |
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| Evid Based Complement Alternat Med. 2014;2014:916531. doi: 10.1155/2014/916531. Epub 2014 May 5. |
| Antihepatoma and liver protective potentials of ganoderma lucidum ( ling zhi) fermented in a medium containing black soybean ( hēi dòu) and astragalus membranaceus ( shēng huáng qí). |
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| Evid Based Complement Alternat Med. 2014;2014:182817. doi: 10.1155/2014/182817. Epub 2014 Feb 10. |
| Effects of Selenium-Enriched Protein from Ganoderma lucidum on the Levels of IL-1 β and TNF- α , Oxidative Stress, and NF- κ B Activation in Ovalbumin-Induced Asthmatic Mice. |
| Min-Chang G, Wei-Hong T, Zhen X, Jie S. |
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